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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
      <bibref>
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      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Modulation of transcriptional corepressor activity of prospero-related homeobox protein (Prox1) by SUMO modification.</fullName>
        </names>
        <bibref>
          <xref>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Modulation of transcriptional corepressor activity of prospero-related homeobox protein (Prox1) by SUMO modification.</attribute>
            <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2008</attribute>
            <attribute name="author-list" nameAc="MI:0636">Shan SF., Wang LF., Zhai JW., Qin Y., Ouyang HF., Kong YY., Liu J., Wang Y., Xie YH.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
            <attribute name="remark-internal">suggested by aryamontri</attribute>
          </attributeList>
        </bibref>
        <xref>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-293t</shortLabel>
              <fullName>Homo sapiens 293 cells transformed with SV40 large T antigen</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>293t</shortLabel>
                <fullName>293 cells expressing SV40 large T antigen.</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ICLC HTL04001" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="IA:0074" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="cabri" dbAc="MI:0246" id="ACC 635" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB.</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti tag coip</shortLabel>
            <fullName>anti tag coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag coip</alias>
          </names>
          <xref>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
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            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Shan SF., Wang LF., Zhai JW., Qin Y., Ouyang HF., Kong YY., Liu J., Wang Y., Xie YH.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
          <attribute name="remark-internal">suggested by aryamontri</attribute>
          <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2008</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>hdac3_human</shortLabel>
          <fullName>Histone deacetylase 3</fullName>
          <alias type="gene name" typeAc="MI:0301">HDAC3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">RPD3-2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SMAP45</alias>
        </names>
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          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UEI5" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UEV0" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
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        </organism>
        <sequence>MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI</sequence>
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          <attribute name="remark-internal">DIP protein O15379 original sequence version: 159</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 161</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 162</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 89</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 156</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 176</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 170</attribute>
          <attribute name="remark-internal">DIP protein O15379-1 original sequence version: 170</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 127</attribute>
          <attribute name="remark-internal">DIP protein O15379-1 original sequence version: 128</attribute>
          <attribute name="remark-internal">DIP protein O15379 original sequence version: 119</attribute>
          <attribute name="crc64">94485C1EBDCF5AD0</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>sumo1_human</shortLabel>
          <fullName>Small ubiquitin-related modifier 1</fullName>
          <alias type="gene name" typeAc="MI:0301">SUMO1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Sentrin</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ubiquitin-like protein SMT3C</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ubiquitin-homology domain protein PIC1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ubiquitin-like protein UBL1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">GAP-modifying protein 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SMT3 homolog 3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SMT3C</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SMT3H3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">UBL1</alias>
          <alias type="orf name" typeAc="MI:0306">OK/SW-cl.43</alias>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000626" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022617" version="SP_195"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029071" version="SP_195"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P63165" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A5R" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1TGZ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1WYW" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y8R" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Z5S" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ASQ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BF8" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2G4D" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IO2" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IY0" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IY1" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2KQS" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LAS" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2MW5" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N1A" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2N1V" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PE6" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2UYZ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2VRR" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3KYC" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3KYD" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RZW" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UIP" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WJN" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WJO" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WJP" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WJQ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5AEK" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5B7A" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ELJ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GHD" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EOP" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EOT" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J4I" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JXU" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6JXV" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6K5T" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6TRW" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYO" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYP" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYQ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYR" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYS" version="SP_195"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000116030" version="SP_195" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000392245" version="SP_195" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000392246" version="SP_195" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005643" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006281" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010621" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015459" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016605" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016607" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016925" version="SP_195"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYU" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYV" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYX" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYY" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYZ" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V7P" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V7Q" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V7R" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UYT" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V7S" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WW3" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XOG" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XOH" version="SP_195"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XOI" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3065676" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3065678" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3065679" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3108214" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3108232" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3232118" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3232142" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3899300" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4085377" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4090294" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4570464" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4615885" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4655427" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4755510" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693565" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693571" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693607" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5696395" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69473" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4551638" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-877312" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8866904" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9615933" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9683610" version="SP_195"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9694631" version="SP_195"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000392244"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000376075"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000376076"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000376077"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001005782.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29080N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 36</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 40</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 124</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 125</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 83</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 85</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 81</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 84</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 103</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 100</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 95</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 98</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 101</attribute>
          <attribute name="remark-internal">DIP protein P63165-1 original sequence version: 131</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 102</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 122</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 62</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 119</attribute>
          <attribute name="remark-internal">DIP protein P63165 original sequence version: 82</attribute>
          <attribute name="crc64">89BE97D2D054FB33</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>prox1_human</shortLabel>
          <fullName>Prospero homeobox protein 1</fullName>
          <alias type="gene name" typeAc="MI:0301">PROX1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Homeobox prospero-like protein PROX1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q92786" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TB91" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A6NK29" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5SW76" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K2B1" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000261454" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000355925" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000400694" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000420283" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3912635" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002754.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001257545.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000117707" version="SP_178" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000261454" version="SP_178" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000366958" version="SP_178" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000435016" version="SP_178" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000498508" version="SP_178" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001227" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001709" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001822" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001889" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001938" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001946" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002088" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002194" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_178"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007420" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007623" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010595" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016922" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0021516" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0021542" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0021707" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0021915" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030240" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030324" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030910" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031016" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031667" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042752" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043049" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043433" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045071" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045737" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045787" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046619" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048845" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050692" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050693" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055005" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055009" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055010" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060042" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060059" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060214" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060298" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060412" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060414" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060421" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060836" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060838" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061114" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070309" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070365" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070858" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072574" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090425" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097150" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901978" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000179" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000979" version="SP_178"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007738" version="SP_178"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009057" version="SP_178"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023082" version="SP_178"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037131" version="SP_178"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039350" version="SP_178"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q92786" version="SP_178"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LMD" version="SP_178"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016857322.1"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MPDHDSTALLSRQTKRRRVDIGVKRTVGTASAFFAKARATFFSAMNPQGSEQDVEYSVVQHADGEKSNVLRKLLKRANSYEDAMMPFPGATIISQLLKNNMNKNGGTEPSFQASGLSSTGSEVHQEDICSNSSRDSPPECLSPFGRPTMSQFDMDRLCDEHLRAKRARVENIIRGMSHSPSVALRGNENEREMAPQSVSPRESYRENKRKQKLPQQQQQSFQQLVSARKEQKREERRQLKQQLEDMQKQLRQLQEKFYQIYDSTDSENDEDGNLSEDSMRSEILDARAQDSVGRSDNEMCELDPGQFIDRARALIREQEMAENKPKREGNNKERDHGPNSLQPEGKHLAETLKQELNTAMSQVVDTVVKVFSAKPSRQVPQVFPPLQIPQARFAVNGENHNFHTANQRLQCFGDVIIPNPLDTFGNVQMASSTDQTEALPLVVRKNSSDQSASGPAAGGHHQPLHQSPLSATTGFTTSTFRHPFPLPLMAYPFQSPLGAPSGSFSGKDRASPESLDLTRDTTSLRTKMSSHHLSHHPCSPAHPPSTAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE</sequence>
        <attributeList>
          <attribute name="crc64">D243CEB421B313CA</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5">
        <names>
          <shortLabel>prox1-hdac3</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787569" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463480" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">PROX1</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787571" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>polyclonal western</shortLabel>
                  <fullName>polyclonal antibody western blot</fullName>
                  <alias type="synonym" typeAc="MI:1041">polyclonal western</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>over-expressed</shortLabel>
                  <fullName>over expressed level</fullName>
                  <alias type="synonym" typeAc="MI:1041">over-expressed</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="7">
                <names>
                  <shortLabel>flag tagged</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787574" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463495" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>flag tag</shortLabel>
                    <fullName>flag tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">FLAG-tagged</alias>
                    <alias type="go synonym" typeAc="MI:0303">FLAG</alias>
                    <alias type="go synonym" typeAc="MI:0303">DYKDDDDKV epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">DYKDDDDKV epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">FLAG</alias>
                    <alias type="synonym" typeAc="MI:1041">FLAG-tagged</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0518" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456503" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="8">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">HDAC3</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787572" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>anti tag western</shortLabel>
                  <fullName>anti tag western blot</fullName>
                  <alias type="synonym" typeAc="MI:1041">anti tag western</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967832" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>over-expressed</shortLabel>
                  <fullName>over expressed level</fullName>
                  <alias type="synonym" typeAc="MI:1041">over-expressed</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="9">
                <names>
                  <shortLabel>ha tagged</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787578" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463492" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>ha tag</shortLabel>
                    <fullName>ha tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">YPYDVPDYA epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">YPYDVPDYA epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F4</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="10">
        <names>
          <shortLabel>prox1-sumo1</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787767" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463533" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">PROX1</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787773" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>polyclonal western</shortLabel>
                  <fullName>polyclonal antibody western blot</fullName>
                  <alias type="synonym" typeAc="MI:1041">polyclonal western</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0086" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-964" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>over-expressed</shortLabel>
                  <fullName>over expressed level</fullName>
                  <alias type="synonym" typeAc="MI:1041">over-expressed</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="12">
                <names>
                  <shortLabel>ha tagged</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787774" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463548" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>ha tag</shortLabel>
                    <fullName>ha tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">YPYDVPDYA epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">YPYDVPDYA epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="13">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">SUMO1</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787769" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>anti tag western</shortLabel>
                  <fullName>anti tag western blot</fullName>
                  <alias type="synonym" typeAc="MI:1041">anti tag western</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967832" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>over-expressed</shortLabel>
                  <fullName>over expressed level</fullName>
                  <alias type="synonym" typeAc="MI:1041">over-expressed</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="14">
                <names>
                  <shortLabel>flag tagged</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787770" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463545" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>flag tag</shortLabel>
                    <fullName>flag tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">FLAG-tagged</alias>
                    <alias type="go synonym" typeAc="MI:0303">FLAG</alias>
                    <alias type="go synonym" typeAc="MI:0303">DYKDDDDKV epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">DYKDDDDKV epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">FLAG</alias>
                    <alias type="synonym" typeAc="MI:1041">FLAG-tagged</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0518" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456503" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
              <feature id="15">
                <names>
                  <shortLabel>undefined mutation</shortLabel>
                  <fullName>mutation disrupting interaction</fullName>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6787778" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8463551" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>mutation disrupting</shortLabel>
                    <fullName>mutation disrupting interaction</fullName>
                    <alias type="synonym" typeAc="MI:1041">mutation disrupting</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0573" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-705401" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>mutation analysis</shortLabel>
                    <fullName>mutation analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0074" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456810" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="96"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="101"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">Wed Jul 06 17:00:31 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was  'mutation disrupting'</attribute>
                  <attribute name="no-mutation-export"/>
                  <attribute name="feature description" nameAc="MI:0597">96-101</attribute>
                  <attribute name="remark-internal">range MINT-6787780: original sequence: 96-101 : DVIEVYQEQTGGHST</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1B</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>