MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Structure and function of A41, a vaccinia virus chemokine binding protein. Structure and function of A41, a vaccinia virus chemokine binding protein. PLoS Pathog. (1553-7366) 2008 rapid curation Bahar MW., Kenyon JC., Putz MM., Abrescia NG., Pease JE., Wise EL., Stuart DI., Smith GL., Grimes JM. Virus - Publications including interactions involving viral proteins suggested by aceol rapid curation in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Bahar MW., Kenyon JC., Putz MM., Abrescia NG., Pease JE., Wise EL., Stuart DI., Smith GL., Grimes JM. Virus - Publications including interactions involving viral proteins suggested by aceol PLoS Pathog. (1553-7366) 2008 rapid curation rapid curation ccl25_mouse C-C motif chemokine 25 Ccl25 Scya25 Teck Small-inducible cytokine A25 Thymus-expressed chemokine Chemokine TECK protein protein mouse Mus musculus Mouse MKLWLFACLVACFVGAWMPVVHAQGAFEDCCLGYQHRIKWNVLRHARNYHQQEVSGSCNLRAVRFYFRQKVVCGNPEDMNVKRAMRILTARKRLVHWKSASDSQTERKKSNHMKSKVENPNSTSVRSATLGHPRMVMMPRKTNN DIP protein O35903 original sequence version: 106 mint Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9 CEC1924B320B4408 a41_vaccw Protein A41 VACWR166 A41L protein protein vaccw vaccinia virus (stra Vaccinia virus (strain WR) VACV MYSLVFVILMCIPFSFQTVYDDKSVCDSDNKEYMGIEVYVEATLDEPLRQTTCESKIHKYGASVSNGGLNISVDLLNCFLNFHTVGVYTNRDTVYAKFASLDPWTTEPINSMTHDDLVKLTEECIVDIYLKCEVDKTKDFMKTNGNRLKPRDFKTVPPSNVGSMIELQSDYCVNDVTTYVKIYDECGNIKQHSIPTLRDYFTTKNGQPRKILKKKFDNC mint 905CE997BBC605D1 ccl26_human C-C motif chemokine 26 CCL26 SCYA26 UNQ216/PRO242 Macrophage inflammatory protein 4-alpha Small-inducible cytokine A26 Eotaxin-3 Thymic stroma chemokine-1 CC chemokine IMAC protein protein human Homo sapiens Human MMGLSLASAVLLASLLSLHLGTATRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKTPKQL mint Chemotactic for eosinophils and basophils. Binds to CCR3 8525B1E4BDD39A5F ccl28_human C-C motif chemokine 28 Mucosae-associated epithelial chemokine CCL28 SCYA28 Small-inducible cytokine A28 Protein CCK1 protein protein human Homo sapiens Human MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY DIP protein Q9NRJ3 original sequence version: 123 Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner mint 3E8551A63A2C8D62 cxl13_mouse C-X-C motif chemokine 13 Cxcl13 Blc Scyb13 Small-inducible cytokine B13 B lymphocyte chemoattractant CXC chemokine BLC protein protein mouse Mus musculus Mouse MRLSTATLLLLLASCLSPGHGILEAHYTNLKCRCSGVISTVVGLNIIDRIQVTPPGNGCPKTEVVIWTKMKKVICVNPRAKWLQRLLRHVQSKSLSSTPQAPVSKRRAA DIP protein O55038 original sequence version: 118 mint Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs F5F8AF4411C56BD3 plf4_human Platelet factor 4 PF4 CXCL4 SCYB4 C-X-C motif chemokine 4 Oncostatin-A Iroplact protein protein human Homo sapiens Human MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES DIP protein P02776 original sequence version: 156 E96C2EFE9B944D85 ccl28_mouse C-C motif chemokine 28 Ccl28 Scya28 Small-inducible cytokine A28 protein protein mouse Mus musculus Mouse MQQAGLTLMAVAVCVAFQTSEAILPMASSCCTEVSHHVSGRLLERVSSCSIQRADGDCDLAAVILHVKRRRICISPHNRTLKQWMRASEVKKNGRENVCSGKKQPSRKDRKGHTTRKHRTRGTHRHEASR Chemotactic for resting CD4, CD8 T-cells and eosinophils (By similarity). Binds to CCR10 and induces calcium mobilization in a dose-dependent manner mint 6F3B909A4F97F013 ccl25_human C-C motif chemokine 25 CCL25 SCYA25 TECK Small-inducible cytokine A25 Thymus-expressed chemokine Chemokine TECK protein protein human Homo sapiens Human MNLWLLACLVAGFLGAWAPAVHTQGVFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPKRHRKVCGNPKSREVQRAMKLLDARNKVFAKLHHNTQTFQAGPHAVKKLSSGNSKLSSSKFSNPISSSKRNVSLLISANSGL DIP protein O15444 original sequence version: 121 mint Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1 91D0810F137FBC7B cc21a_mouse C-C motif chemokine 21a Ccl21a Scya21 Scya21a Ccl21c Scya21c Small-inducible cytokine A21a Small-inducible cytokine A21c 6Ckine Thymus-derived chemotactic age Beta-chemokine exodus-2 protein protein mouse Mus musculus Mouse MAQMMTLSLLSLVLALCIPWTQGSDGGGQDCCLKYSQKKIPYSIVRGYRKQEPSLGCPIPAILFLPRKHSKPELCANPEEGWVQNLMRRLDQPPAPGKQSPGCRKNRGTSKSGKKGKGSKGCKRTEQTQPSRG Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs mint 7071750A2089A70B ccl21_human C-C motif chemokine 21 Small-inducible cytokine A21 Beta-chemokine exodus-2 6Ckine Secondary lymphoid-tissue chemokine CCL21 SCYA21 UNQ784/PRO1600 protein protein human Homo sapiens Human MAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSKGCKRTERSQTPKGP FB48C2F71CB4A9D2 groa_mouse Growth-regulated alpha protein Platelet-derived growth factor-inducible protein KC Cxcl1 Gro Gro1 Mgsa Scyb1 C-X-C motif chemokine 1 Secretory protein N51 protein protein mouse Mus musculus Mouse MIPATRSLLCAALLLLATSRLATGAPIANELRCQCLQTMAGIHLKNIQSLKVLPSGPHCTQTEVIATLKNGREACLDPEAPLVQKIVQKMLKGVPK Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation (By similarity). Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity mint 4A52B5E5C38B45C2 ccl21-a41 1 3 unspecified role unspecified role prey prey CCL21 11 unspecified role unspecified role bait bait physical association physical association T1 T2 homomint mint ccl21a-a41 1 10 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association T1 T2 mint ccl28-a41 1 5 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association T1 T2 homomint mint ccl28-a41-1 1 8 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association T1 T2 homomint mint ccl25-a41 1 3 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association T1 T2 homomint mint ccl25-a41-1 1 3 unspecified role unspecified role prey prey 2 unspecified role unspecified role bait bait physical association physical association T1 T2 mint ccl26-a41 1 4 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association T1 T2 homomint mint pf4-a41 1 3 unspecified role unspecified role prey prey 7 unspecified role unspecified role bait bait physical association physical association T1 T2 homomint mint cxcl1-a41 1 12 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association T1 T2 mint cxcl13-a41 1 6 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association T1 T2 homomint mint