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        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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        <names>
          <fullName>Modulation of nucleobindin-1 and nucleobindin-2 by caspases.</fullName>
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            <attribute name="publication title" nameAc="MI:1091">Modulation of nucleobindin-1 and nucleobindin-2 by caspases.</attribute>
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            <attribute name="publication year" nameAc="MI:0886">2008</attribute>
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            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
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            <shortLabel>protease assay</shortLabel>
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          <shortLabel>nucb1_human</shortLabel>
          <fullName>Nucleobindin-1</fullName>
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          <alias type="gene name synonym" typeAc="MI:0302">CALNUC</alias>
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            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
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        <sequence>MPPSGPRGTLLLLPLLLLLLLRAVLAVPLERGAPNKEETPATESPDTGLYYHRYLQEVIDVLETDGHFREKLQAANAEDIKSGKLSRELDFVSHHVRTKLDELKRQEVSRLRMLLKAKMDAEQDPNVQVDHLNLLKQFEHLDPQNQHTFEARDLELLIQTATRDLAQYDAAHHEEFKRYEMLKEHERRRYLESLGEEQRKEAERKLEEQQRRHREHPKVNVPGSQAQLKEVWEELDGLDPNRFNPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQDRLVTLEEFLASTQRKEFGDTGEGWETVEMHPAYTEEELRRFEEELAAREAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQQQQQQGHKAPAAHPEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL</sequence>
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      <interactor id="3">
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          <shortLabel>casp3_human</shortLabel>
          <fullName>Caspase-3</fullName>
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          <alias type="gene name synonym" typeAc="MI:0302">Cysteine protease CPP32</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein Yama</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SREBP cleavage activity 1</alias>
          <alias type="gene name" typeAc="MI:0301">CASP3</alias>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUH" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUI" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUD" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUJ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUL" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I9B" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I9T" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAB" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAE" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAG" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUE" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAJ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUG" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAN" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAR" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IAS" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IBC" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IBP" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IBR" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IC4" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111459" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111463" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111465" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111469" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-140342" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1474228" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2028269" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-205025" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-211736" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-264870" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-351906" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418889" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-449836" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5620971" version="SP_235"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111464" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1QX3" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RE1" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHJ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHM" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHQ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHR" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RHU" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C1E" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C2K" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C2M" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C2O" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CDR" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CJX" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CJY" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CNK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CNL" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CNN" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CNO" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2DKO" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2H5I" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2H5J" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2H65" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J30" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J31" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J32" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J33" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XYG" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XYH" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XYP" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XZD" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XZT" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Y0B" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DEH" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1PAU" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DEI" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DEJ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DEK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EDQ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GJQ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GJS" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GJT" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3H0E" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ITN" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3KJF" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PCX" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PD0" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PD1" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DCJ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DCO" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4DCP" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHA" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHD" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHF" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHH" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHK" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHL" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EHN" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JJE" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JQY" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JQZ" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JR0" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PRY" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PS0" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QTX" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3GJR" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QTY" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QU0" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QU5" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QU8" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QU9" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUA" version="SP_235"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4QUB" version="SP_235"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011530603.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004337.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_116786.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-268N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 108</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 171</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 111</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 105</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 131</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 132</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 134</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 162</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 189</attribute>
          <attribute name="remark-internal">DIP protein P42574 original sequence version: 167</attribute>
          <attribute name="crc64">2F35CD3BCF7FF64A</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>casp6_human</shortLabel>
          <fullName>Caspase-6</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Apoptotic protease Mch-2</alias>
          <alias type="gene name" typeAc="MI:0301">CASP6</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MCH2</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P55212" version="SP_85" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BQE7" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000265164" version="SP_217" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-718729" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001217.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_116787.1"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K7E" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3NKF" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3NR2" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3OD5" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P45" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3P4U" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QNW" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3S70" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3S8E" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3V6L" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3V6M" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EJF" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FXO" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4HVA" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IYR" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N5D" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N6G" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N7J" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4N7M" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NBK" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NBL" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4NBN" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DEU" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DEV" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111465" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-264870" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-352238" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6803207" version="SP_217"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000138794" version="SP_217" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000265164" version="SP_217" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004197" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008234" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030855" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072734" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097153" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097200" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001309" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002138" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002398" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015917" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016129" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029030" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033139" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037554" version="SP_217"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P55212" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MI9" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WDP" version="SP_217"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-44649N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSSASGLRRGHPAGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKSN</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P55212 original sequence version: 118</attribute>
          <attribute name="crc64">0738AE4F9791EBD7</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>casp7_human</shortLabel>
          <fullName>Caspase-7</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">ICE-like apoptotic protease 3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Apoptotic protease Mch-3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CMH-1</alias>
          <alias type="gene name" typeAc="MI:0301">CASP7</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MCH3</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P55210" version="SP_83" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B5BU45" version="SP_111" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5SVL3" version="SP_111" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13364" version="SP_83" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96BA0" version="SP_83" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5SVL0" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53YD5" version="SP_99" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000298701" version="SP_217" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000358321" version="SP_217" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000358324" version="SP_217" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000480584" version="SP_217" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DRB8" version="SP_119" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DQU7" version="SP_138" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-523958" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001218.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203124.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203125.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203126.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000165806" version="SP_217" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000345633" version="SP_217" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_217"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000369315" version="SP_217" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007507" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008233" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008234" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009411" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016485" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051146" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051402" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071887" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072734" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097153" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097194" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097200" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001309" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002138" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002398" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015471" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015917" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016129" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029030" version="SP_217"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033139" version="SP_217"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P55210" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1F1J" version="SP_217"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000369318" version="SP_217" refType="transcript"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1GQF" version="SP_217"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000621345" version="SP_217" refType="transcript"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1I4O" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1I51" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1K86" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1K88" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1KMC" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MIA" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SHJ" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004190" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SHL" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QL5" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004197" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QL7" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QL9" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QLB" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QLF" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QLJ" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EDR" version="SP_217"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3H1P" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3IBC" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3IBF" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3R5K" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FDL" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FEA" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4HQ0" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4HQR" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JB8" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111464" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111465" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111469" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-264870" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JJ8" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JR1" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4JR2" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LSZ" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVO" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVP" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVQ" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVR" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVS" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVT" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ZVU" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IC6" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5K20" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5V6U" version="SP_217"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5V6Z" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111459" version="SP_217"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-111463" version="SP_217"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001253986.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001253987.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001253985.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001307840.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29973N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P55210 original sequence version: 92</attribute>
          <attribute name="remark-internal">DIP protein P55210 original sequence version: 114</attribute>
          <attribute name="remark-internal">DIP protein P55210 original sequence version: 118</attribute>
          <attribute name="crc64">CD373EE54A232CA4</attribute>
        </attributeList>
      </interactor>
      <interactor id="6">
        <names>
          <shortLabel>nucb2_human</shortLabel>
          <fullName>Nucleobindin-2</fullName>
          <alias type="gene name" typeAc="MI:0301">NUCB2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NEFA</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA-binding protein NEFA</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Gastric cancer antigen Zg4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Prepronesfatin</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Epididymis secretory protein Li 109</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P80303" version="SP_77" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DQX5" version="SP_114" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K642" version="SP_77" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8NFT5" version="SP_77" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="V9HW75" version="SP_160" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000436455" version="SP_187" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000481959" version="SP_187" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2296670" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005004.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873295.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873296.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873297.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873298.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873299.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873300.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873301.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873302.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873303.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873304.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873305.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873306.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873307.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873308.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000070081" version="SP_187" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000529010" version="SP_187" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000622082" version="SP_187" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001965" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005085" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005793" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007264" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032099" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_187"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002048" version="SP_187"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992" version="SP_187"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018247" version="SP_187"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028813" version="SP_187"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_187"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040250" version="SP_187"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P80303" version="SP_187"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI</sequence>
        <attributeList>
          <attribute name="crc64">ABA74587B72C33FE</attribute>
        </attributeList>
      </interactor>
      <interactor id="7">
        <names>
          <shortLabel>casp8_human</shortLabel>
          <fullName>Caspase-8</fullName>
          <alias type="gene name" typeAc="MI:0301">CASP8</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MCH5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ICE-like apoptotic protease 5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MORT1-associated ced-3 homolog</alias>
          <alias type="gene name synonym" typeAc="MI:0302">FADD-homologous ICE/ced-3-like protease</alias>
          <alias type="gene name synonym" typeAc="MI:0302">FADD-like ICE</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Apoptotic cysteine protease</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Apoptotic protease Mch-5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CAP4</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q14790" version="SP_107" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000412523" version="SP_246" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000501268" version="SP_246" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14793" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14794" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14795" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14796" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q15780" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q15806" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53TT5" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TDI1" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TDI2" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TDI3" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TDI4" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TDI5" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96T22" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9C0K4" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14676" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14791" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14792" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UQ81" version="SP_107" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-78060" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007507" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008233" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008234" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008625" version="SP_246"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000064012" version="SP_246" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000432109" version="SP_246" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000673742" version="SP_246" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001525" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001817" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004197" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005123" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005164" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_246"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_246"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001875" version="SP_246"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033170" version="SP_246"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q14790" version="SP_246"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1F9E" version="SP_246"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1I4E" version="SP_246"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C2Z" version="SP_246"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FUN" version="SP_246"/>
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          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9686347" version="SP_246"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9693928" version="SP_246"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001073593.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001073594.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001219.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203519.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203520.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_203522.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006712852.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006712853.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_006712856.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005246944.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005246945.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005246946.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005246947.1"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005246949.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005246943.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-30915N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 184</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 135</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 136</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 147</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 146</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 170</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 198</attribute>
          <attribute name="remark-internal">DIP protein Q14790-1 original sequence version: 197</attribute>
          <attribute name="remark-internal">DIP protein Q14790 original sequence version: 158</attribute>
          <attribute name="crc64">7A5FEAA6B39B582F</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="8" imexId="IM-13958-1">
        <names>
          <shortLabel>casp6-nucb1</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175501" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740813" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-13958-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="9">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CASP6</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175503" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="10">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">NUCB1</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175504" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>in vitro translated</shortLabel>
                  <fullName>in vitro translated protein</fullName>
                  <alias type="synonym" typeAc="MI:1041">in vitro translated</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0589" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537803" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="11">
                <names>
                  <shortLabel>binding site</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175508" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740826" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="236"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="240"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">range MINT-6175509: original sequence: 236-240 : AQLKEVWEELDGLDPNRFNPKTFF</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>cleavage</shortLabel>
            <fullName>cleavage reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">cleavage</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1B F1E</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="12" imexId="IM-13958-2">
        <names>
          <shortLabel>casp8-nucb1</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175515" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740846" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-13958-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="13">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CASP8</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175517" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>7</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="14">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">NUCB1</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175519" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>in vitro translated</shortLabel>
                  <fullName>in vitro translated protein</fullName>
                  <alias type="synonym" typeAc="MI:1041">in vitro translated</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0589" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537803" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="15">
                <names>
                  <shortLabel>binding site</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175520" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740859" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="236"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="240"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">range MINT-6175521: original sequence: 236-240 : AQLKEVWEELDGLDPNRFNPKTFF</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>cleavage</shortLabel>
            <fullName>cleavage reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">cleavage</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1B F1E</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="16" imexId="IM-13958-3">
        <names>
          <shortLabel>casp8-nucb2</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175525" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740879" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-13958-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="17">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CASP8</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175527" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>7</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="18">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">NUCB2</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175529" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>6</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>in vitro translated</shortLabel>
                  <fullName>in vitro translated protein</fullName>
                  <alias type="synonym" typeAc="MI:1041">in vitro translated</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0589" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537803" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="19">
                <names>
                  <shortLabel>binding site</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175530" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740892" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="175"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="269"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">range MINT-6175531: original sequence: 175-269 : EEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEA</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>cleavage</shortLabel>
            <fullName>cleavage reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">cleavage</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1C</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="20" imexId="IM-13958-4">
        <names>
          <shortLabel>casp7-nucb2</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175536" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740913" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-13958-4" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="21">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">NUCB2</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175538" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>6</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>in vitro translated</shortLabel>
                  <fullName>in vitro translated protein</fullName>
                  <alias type="synonym" typeAc="MI:1041">in vitro translated</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0589" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537803" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="22">
                <names>
                  <shortLabel>binding site</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175539" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740926" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="175"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="269"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">range MINT-6175540: original sequence: 175-269 : EEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEA</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
          <participant id="23">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CASP7</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175542" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>5</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>cleavage</shortLabel>
            <fullName>cleavage reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">cleavage</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1C</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="24" imexId="IM-13958-5">
        <names>
          <shortLabel>casp6-nucb2</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175546" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740930" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-13958-5" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="25">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">NUCB2</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175550" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>6</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>in vitro translated</shortLabel>
                  <fullName>in vitro translated protein</fullName>
                  <alias type="synonym" typeAc="MI:1041">in vitro translated</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0589" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537803" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="26">
                <names>
                  <shortLabel>binding site</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175551" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740943" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="175"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="269"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">range MINT-6175552: original sequence: 175-269 : EEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEA</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
          <participant id="27">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CASP6</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175548" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>cleavage</shortLabel>
            <fullName>cleavage reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">cleavage</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1C</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
      <interaction id="28" imexId="IM-13958-6">
        <names>
          <shortLabel>casp3-nucb2</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175556" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740963" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-13958-6" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="29">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">CASP3</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175558" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="30">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">NUCB2</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175560" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>6</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>in vitro translated</shortLabel>
                  <fullName>in vitro translated protein</fullName>
                  <alias type="synonym" typeAc="MI:1041">in vitro translated</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0589" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537803" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="31">
                <names>
                  <shortLabel>binding site</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-6175561" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7740994" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="175"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="269"/>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="remark-internal">range MINT-6175562: original sequence: 175-269 : EEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEA</attribute>
                </attributeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>cleavage</shortLabel>
            <fullName>cleavage reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">cleavage</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F1C</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>