MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Multiple interactions among proteins encoded by the mite-transmitted wheat streak mosaic tritimovirus. Multiple interactions among proteins encoded by the mite-transmitted wheat streak mosaic tritimovirus. Virology (0042-6822) 2000 Choi IR., Stenger DC., French R. Virus - Publications including interactions involving viral proteins in vivo in vivo 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Choi IR., Stenger DC., French R. Virus - Publications including interactions involving viral proteins Virology (0042-6822) 2000 polg_bstv1 Genome polyprotein protein protein bstv Brome streak virus (strain 11-Cal) MQQTHVKQVWRPKTASSKVKTSNMVYLAEESSPLAKTELKEDAVVAADMSVINADDAVYGHALEGKYSERKALPARSNETIVSFASGEDGLFLDRAACGSIFKTRTGKDTPIATAIRAATRRGLAYDIAAQLYMCPKCCSASDKVLYFDTNHNDSCQWYLDNCRAVINKDWTLDVIETYNVFPVLVTEEEERRTLEAVDIALKPLGTVPVHDVVQVYDQKIGEHKEVERNQEAAHGSEPAIITTTPVLRRQCIEKRLLRHVHQANKVIANTVEIYDLMTETSQICAEKAIPLVFVDYEKKKRIRPRVPLRHVLESNNVDPSDDLYADVVPFLKHYGTCGRPVGVINPRDIKPGWSGVVLLQDELPESLHQECVDGVFVVQGIGPDGQLKNALKTTTGERIEYYSSKRRMAVNAHVPKAHSFCKYSSLTETLMELDYLRVISALADVHDPQCVECHKERNERSFIENLKYTQQGAQNLFNAGTGMGLAFVASIASGQLMIQRQQPQSSSSIVDQTPRTNEDGSLSHNINLLLTPEVVDIWRSMKQMVHLPNRKLYMASFNDQFGNFDFIPNSTLQGVFPDFTMPVTIALNDDDKVETNYRHVDKNSTIETCVEGLYTQFDAAYWTKKAAQVHKIQPIDQCGMEIGNIALKLCHWEGDVALFSPIIRPTPGHLMFGSTDRLLRIPDMTNARHYVPKVGYCYLYLFALAMNFCDGENRVTVDAYINKTCRELGAWPKFGEVLRALDRMATYYGCYDAVVPVMLVDHVQRTIHVPSPFGIVQSGMHMIQINNLGDLIKLDTMGASELKEYEIGGFRETYKSITKCVKSKSAFMEKLNQDNEWLVDMICNPSTLFVLSQLMDTHGLILKDVENSFDRLAALLALKELGSALGPLLTTRKRVALYMQSLSKVDELVPHLGMPTGAMNLLKSEIELIQNAIVEEQDMAEIDRVEGKKSILERRDEMFAPCVYNEFINSFGYVSLPGIAYRLTYTGVGARIGRGCEHLKTVWSGSWIPEIHLPENLRSNTWSAIKKYTVYSGGTAWRYMKLKIVESATQILVAAVITAIGSWLLKKLLKFIRHEKGRLNEVVVFQSKQEELFISKFMAVCFVISTFFSLDMSNAIYSSLTKFRAIFSILSVGSIYQSGALEKLEEQLGHVDTFHEFKLYDHDATHANIAPSVQSFGTWLDTRVLAGQQGCDPLEGRHTKFEMNKNTRDAIAARVLADKDNEFLVMGHVGCGKSTYFPVALSKQARVLICEPTRVLVTNLHDSMMHTCQVAPSVMMRNHRCITGSSIMVQTYGFALHYLVNNPENLQQYDFVLFDEVHHTCAEKVVLYNWLKGRDWGGKIVKLTATDRSPSAEIKAQKSLDIMTLPTMTPLDFVKEQGLSTKADASKHGKVILVFLTSFREVDSCYDELKRKENFDAIKADSRNLRNKTSLADLISECKKEFIYIFATNILQTGINIEADVVVDFGYKIVPTYDVDNRMLTTTRKPVNKADRIQRLGRVARMKAGVAMKIGATIDPEAYDDEVTATEAALLSFAMQVPPVLRNVNLQIFQRITREQVVTAARFEHQLSYMVWMVNKDGSMPTKLYDLFSPLLLSQGNMRLSPYYSSLYDSDTFMTVKNYVDIGYLKHDRTTNQRLPFHCHDVSTTFAMKVADRFEDSRAPSTYSIRVPAVNLRHTAVKLSTDPAQVGMILVVIGEALVHQKNILEQLKSTRTQLDNYNSCILVPNWNVRGKLDDAINRVERNVSILENQKNSVEKMSVARGYDELKELLEENHAVAAHVMYQKGPQKFIDDVLLQKRDFSWMPYISVGAACLMAGCAWYMLYRQRAKHEAKFEGKASRVKASKQKAFDDKMARADNYTYYETTDELHNHAREWNDYPTDWVDKVRKKANVHAMQFGREAPRRDVRNDRPFFNFYGIDEKLYDTVTFHDMAASFSVEQPITAMEVEEAFEKIYLNRQEDEAFFDHPMPKKILAEFKGKDGKVINVEMEPHNPRKANRRGLPVGYADHRGEFRQAKPAEEGPIKFERKALNPKATPYAVFESKALYGGPRCYEHITNNQVLLAGPSGYLNGLITGSKLLAPYHFVKDISSDSQDPSRMIARFGTYNLGNILNLQVVKFTMIDLIGLDLPVEFQPRRTLKCFRVPVIGEKAVLVLSRYSKEGWKSCVSAETEITPYGENEELLWRHRITTEVGDCGATMVALSDQKIVGFHSLGGISMNYFVPVTQELLDFLSSKTEKPLVPWRFSEDQVDVGGLYIHNDFDKFPFVKTIQKLVGFQNGHMIKYCGEGFTPVARSENRLSRQHVISGQRESFIHFVEASSKWRPLITPMLGRLQPSALNREAYYKDVLKYDKPIRLGTVHEEAFQSAVINVIRILENAGFERGGVKACFDYGKIFNDLNLDAAMGALYAGKKKDYFVEATDEEIEEMFLRSAGKICANGHGVWSALLKAELRPAEKVAANKTRTFTSAPIDILFGAKAVVDDFNKQFYKRHLLGPWTVGINKFNKGWDLLARSLMRYEWFIDADGSQFDSSITPLLMNAVLTIRLYFMERDDITELMLRNLYTQIISTCMLAEDGLIVQKHRGNNSGQPSTVVDNTLCLMIAMEYARQRAISDGHLNMQMRYVCNGDDLLINANEEAKDVVQGKYEQYIKELELNYCFDDAFQSIEGVEFMSHKFMLRNGIYIPKLARHRIVAILEWQRSAEPQAIKSAILAACVEAFGYDDLTELIREYAISLEPVWGSFLPTDGEIEQLYFEGIAKQEVARCLAGVDDVCKFESAASGTNEAVDEVLKAAGDDEALARANAAATSGATTPAQNVGAGTTTPAKATPQSGRRPSFGSLIDNPIGGNGVQDVADRTSGIVFPVPTRKSTSLYLPPKVKLRATPERIEKVRKYLPDPQQIDLRYSTQQELNDWIKASADGLGQTEEAFIDNILPGWIVHCIVNTTSSENRKAGSWRCVTNAGTADEEQVLYDIEPMYSAANPTMRAIMRHFSDLARLVIAESFKQGRPLIPKGYIKAGVLDASSAAAACDFVVRDRHDTATFVQVQNQVLVNRVSGITNRLFAQAMPSAGANEDMARHDAQDAAEGIHNLGGARAF mint Coat protein is involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification Nuclear inclusion protein B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication Helper component proteinase is required for aphid transmission and also has proteolytic activity. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity Cytoplasmic inclusion protein has helicase activity. It may be involved in replication Both 6K peptides are indispensable for virus replication Nuclear inclusion protein A has RNA-binding and proteolytic activities 50F775CEF7ABCCB4 polg-polg-9 1 2 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain HC-PRO range MINT-382952: original sequence: 404-809 : SSKRRMAVNAHVPKAHSFCKYSSLTETLMELDYLRVISALADVHDPQCVECHKERNERSFIENLKYTQQGAQNLFNAGTGMGLAFVASIASGQLMIQRQQPQSSSSIVDQTPRTNEDGSLSHNINLLLTPEVVDIWRSMKQMVHLPNRKLYMASFNDQFGNFDFIPNSTLQGVFPDFTMPVTIALNDDDKVETNYRHVDKNSTIETCVEGLYTQFDAAYWTKKAAQVHKIQPIDQCGMEIGNIALKLCHWEGDVALFSPIIRPTPGHLMFGSTDRLLRIPDMTNARHYVPKVGYCYLYLFALAMNFCDGENRVTVDAYINKTCRELGAWPKFGEVLRALDRMATYYGCYDAVVPVMLVDHVQRTIHVPSPFGIVQSGMHMIQINNLGDLIKLDTMGASELKEYEI Stoichiometry: 1.0 2 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain CI range MINT-382945: original sequence: 1139-1783 : SGALEKLEEQLGHVDTFHEFKLYDHDATHANIAPSVQSFGTWLDTRVLAGQQGCDPLEGRHTKFEMNKNTRDAIAARVLADKDNEFLVMGHVGCGKSTYFPVALSKQARVLICEPTRVLVTNLHDSMMHTCQVAPSVMMRNHRCITGSSIMVQTYGFALHYLVNNPENLQQYDFVLFDEVHHTCAEKVVLYNWLKGRDWGGKIVKLTATDRSPSAEIKAQKSLDIMTLPTMTPLDFVKEQGLSTKADASKHGKVILVFLTSFREVDSCYDELKRKENFDAIKADSRNLRNKTSLADLISECKKEFIYIFATNILQTGINIEADVVVDFGYKIVPTYDVDNRMLTTTRKPVNKADRIQRLGRVARMKAGVAMKIGATIDPEAYDDEVTATEAALLSFAMQVPPVLRNVNLQIFQRITREQVVTAARFEHQLSYMVWMVNKDGSMPTKLYDLFSPLLLSQGNMRLSPYYSSLYDSDTFMTVKNYVDIGYLKHDRTTNQRLPFHCHDVSTTFAMKVADRFEDSRAPSTYSIRVPAVNLRHTAVKLSTDPAQVGMILVVIGEALVHQKNILEQLKSTRTQLDNYNSCILVPNWNVRGKLDDAINRVERNVSILENQKNSVEKMSVARGYDELKELLEENHAVAAHVMY Stoichiometry: 1.0 physical association physical association homomint mint