IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J. Biol. Chem. (0021-9258) 2002 Kuroda TS., Fukuda M., Ariga H., Mikoshiba K. Synapse - Interactions of proteins with an established role in the presynapse. Chromatin - Epigenetic interactions resulting in chromatin modulation chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip polyclonal western polyclonal antibody western blot polyclonal western Kuroda TS., Fukuda M., Ariga H., Mikoshiba K. Synapse - Interactions of proteins with an established role in the presynapse. Accepted 2010-JAN-10 by SKERRIEN (applied to all records created before 2005-Sep-01). J. Biol. Chem. (0021-9258) 2002 sytl1_mouse Synaptotagmin-like protein 1 Sytl1 Slp1 Exophilin-7 protein protein mouse Mus musculus Mouse MPQRGHPSQERLWALPSLPMAHGPGSEVEGLLDLSFLTEEEQEAISDVLKRDAHLRQLEEGRVSKLRASLEDPWQLKILTGDWFQEARSQRHHHAHFGSDLVRASIRRKKSPKGDQALGSDGEAEAAGEDTIEGEPESRVSIEVAAPERSTETQGPDLSSPYVPSKASEGQEEEPQDHECELEAPGEGGVQVAEADPELDPEQKAEQESQPTPAQSKATSKILENGEEAPGLGPSLDRMLSSSSSVSSLNSSTLSGSLMSLSGEEAGTVQVRGSVLFSLHYEPGTSELRVQVIQCQGLAAARRRRSDPYVKSYLLPDKQSKRKTSVKKRNLNPIFNETLRHSVQQADLPGRVLSLSVWHRESLGRNIFLGEVEVPLDTWNWDSEATWLPLQPRVPPSPDELPSRGLLSLSLKYVPAGSEGGGQPQSGELHFWVKEAQSLVPLRPGSLDTYIQCSVLPDDSRASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWDHGALASRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQTLLERPCEWVDGLLPLRTNLVPRA 13ACC780131F65FB sytl4_mouse Synaptotagmin-like protein 4 Sytl4 Slp4 Exophilin-2 Granuphilin protein protein mouse Mus musculus Mouse MSEILDLSFLSEMERDLILGVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQEGLGRLIPKSSTCVGCNHLVCRECRVLESNGSWRCKVCSKEIELKKATGDWFYDQKVNRFDYRTGSEIIRMSLRQKPAVNKRETAGQSLLQQTQMGDIWPGRRIIQEQQQREQSVLFEVPKTRSGKSALEAESESLDSYTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKEIPPGNQNAVCGDEGDMVFKKNTKKVLRPSEYTKSVIDLRPEDVAQESGILGDRSKSVPGLSVDMEEEEEEEEDIDHLVKLHRQKLARGSMQSGSSMSTLGSIMSIYSEAGDFGNISVTGKIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTESSPGLPAHKGELVVSLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLSPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMVKQKLGV 2AC218E2A4BE4C8D rp3a_mouse Rabphilin-3A Rph3a Exophilin-1 protein protein mouse Mus musculus Mouse MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQERIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKICLEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRPPGQKPGPDLTSAPGRGSHGPPTRRASEARMSTAARDSEGWDHAHGGGTGDTSRSPAGLRRANSVQAARPAPAPVPSPAPPQPVQPGPPGGSRATPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPAGGFQAAPHTAAPYSQAAPARQPPPAEEEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD D09F8D8D2CBB271E sytl3_mouse Synaptotagmin-like protein 3 Sytl3 Slp3 Exophilin-6 protein protein mouse Mus musculus Mouse MAHEVDLESFKELERDIILRVLYRDQTVQSTEEERVRKLKSHLQHLRWKGAKSSSQEYKEKCCARCQRALGLLLNRGAVCQGCSHRVCSECRVFLRRTRAWKCTVCFEDRNVKIKTGEWFFEERARKFPTAGRRETAGAKLLQSYQRLSKISVVPPTPPPFSESQCSSSSRLQELGHFRGFNKSVENLFLSVTTQMRKLSKSQNDMTSEKHLLAMDPRQCVGHTERRSQSDTAVNVTSRKASTPDILKAFHQEDPKHPPDPVLKQDTPPSSPTHSAVFSGGLRHGSLISINSTCTEMGNFDNANVTGEIEFAIHYCVKSCSLEICIKTCKNLAYGEEKKRKCNPYVKTYLLPDRSSQGKRKTRVQKNTLDPTFEETLKYQVDPGQLMTRRLQVSVWHLGTLARRVFLGEVILPLAMWDFKDSTAQNARWYPLRAKAEKYEENIPQNNGELAVRAKLVLPAGPRKPQEAQEGQLALNGQLCLVVLGAKNLPVRSDGTLNSFVKGCLTLPNQQKLRVKSPVLKKQACPQWKHSFVFNGVSSSQLRQSTLELTVWDQAIFGMNDRLLGEARLGSKGGAAGCPDSGSQSKLQWHRVLSSPNLWTDMTLVLH F9F404D2D77A6351 rab8a_mouse Ras-related protein Rab-8A Rab8a Mel Rab8 Oncogene c-mel protein protein mouse Mus musculus Mouse MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRCSLL DIP protein P55258 original sequence version: 143 AC89DC85588FB8F8 rb27a_mouse Ras-related protein Rab-27A Rab27a protein protein mouse Mus musculus Mouse MSDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGAVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCVDKSWIPEGVVRSNGHTSADQLSEEKEKGLCGC DIP protein Q9ERI2 original sequence version: 64 C6857EBDD7F38137 melph_mouse Melanophilin Mlph Ln Slac2a Exophilin-3 Leaden protein Synaptotagmin-like protein 2a Slp homolog lacking C2 domains a protein protein mouse Mus musculus Mouse MGKRLDLSTLTDEEAEHVWAVVQRDFDLRRREEERLQGLKGKIQKESSKRELLSDTAHLNETHCARCLQPYRLLLNSRRQCLECSLFVCKSCSHAHPEEQGWLCDPCHLARVVKIGSLEWYYQHVRARFKRFGSAKVIRSLCGRLQGGGGSEPSLEEGNGDSEQTDEDGDLDTEARDQPLNSKKKKRLLSFRDVDFEEDSDHLVQPCSQTLGLSSVPESAHSLQSLSGEPYSEDTTSLEPEGLEETGARALGCRPSPEVQPCSPLPSGEDAHAELDSPAASCKSAFGTTAMPGTDDVRGKHLPSQYLADVDTSDEDSIQGPRAASQHSKRRARTVPETQILELNKRMSAVEHLLVHLENTVLPPSAQEPTVETHPSADTEEETLRRRLEELTSNISGSSTSSEDETKPDGTFLGGSPKVCTDTGHMETQERNPRSPGNPARPTKSTDEELSEMEDRVAMTASEVQQAESEISDIESRIAALRAAGLTVKPSGKPRRKSGIPIFLPRVTEKLDRIPKTPPADPDDQAKMPKATTAVPSLLRRKYSPSSQGVDSGSFDRKSVYRGSLTQRNPNGRRGTARHIFAKPVMAQQP DIP protein Q91V27 original sequence version: 54 C91444B16B8EFA1D exph5_mouse Exophilin-5 Exph5 Kiaa0624 Slac2b Synaptotagmin-like protein homolog lacking C2 domains b protein protein mouse Mus musculus Mouse MTKVPQGFDFSFLNEEEARKILQVLERNEELRRAEKDRISKLQKTKRDIRWLQGATGEWFEEIQRKKFCNETDVNQMLKPPLTYRLQKGMAKNDPMELQTPRSKSLINQKPSVSSRMSFRSSFASLFSFRRPAKETLKLQSPRPNRCDERVRPSASVRGTASAKIYNSPVGNQPVASVFVPKPAIMREESGMPPPWDASLLESEFFQVLDDLDNKLAQEQSSGLMNTRVPFNYGSRTQFKLSHRNSHGHSTGRQQNYHSETSNMSIYNILRPGTPREGFKTFSPRTKTIYDMYRTREPRVLKEDFMQKNAFGSASLCFDSRQRSASPATGSFTARSLHFPADTQNKSSFTPVRHQQSPKRTPLSSIIWNRSDASRHRQNQEESLGVQAPMDIDPEEQYVSPRCFQESRRYEMCHSQNAYQSYPLNVPVANAMSPDTLENSENMPFYRQSNPFARSFFSSTFRQSREQRFGQNSFWSRQEEYSSWSDFPQSRGPFPSSDKDFEMFSVEANRAPSVCSQGVPSQHWRSHSSGHGTYVFRGREDSHCWRSDFQTSPLESMDTSHVNENQHPPHFVTPVGFSITDSSCHLQSSRLDSQQGYFPVEEAVDEDPYLCGKAQTPASSFRTPFPLSPDDGRESQSSSFPDSTATLQKIIPNKPDFLPIRNCTEVPVACSHSTDSLSLTDTQPNIPVTETNSEKDMDVSVSKDEQLNKTGQKSRPTGLPQYVLHTVISNDLPDFQNAHSRDSAQNDRYGFNAPATERSRRSPRVFSRKGTSQIHTTQRDQSNKLSKNKCFGGDRTLDSAASPPFIQESGTATSLPSPNQGCHQKTGSNEESSNTIKNSHWCFESTANQKSQPSREPALLDLEQSLSTHSTNDSKLAPGHSISRAPLHVASDAPQESFLDARLVPSTTVFSRSLSDQDPGQEQREEKDKATKSQDNQLAVNSTDNQESHDSPALPHDAVHCHPYSPFKNGRGKGRVRRRVSCIEKLTKTERAAAPTREGSGCAEDQRSIKDPELSTVYCTLPRKPASFLIHSRQQESKGTVASVRNGPLPFQIKNKAEVPTGKSTSDKPSSPESVSDAANAVSGTPKATKKMTDMKAIRSASVRKGPLPFLIKRAISCPSGEPCSLAESDDRQKSSVLGMDASPVIPRPGGRIFNSLEGEPSFRESAFSEKELAQEHTGKDRELRAPRMGLFNPSKKTPERLCATGSGKESGRALHKFKTTSMFSVSGDEENVNCLEVVSIYYTLPRKPSKKFCSLLQQYTQGTDSLRDAFQGETEALPNALEIDELNCPAQVQSGIPPPQDPKMQVDSAPCCLSHSPESKDVSQLPDRETSKSTLEEMTSVGPDVSLHREEPTTKEISPSNVSKTAIDDSLSREKREKELLRQILRAPLLHQEKGAGKEHTKSHQQPSKGGNSGPSGLPSRSEDNDENSQTRRDSGTCAGGMASGNGQYPWRDHMAAVVGDRSSRSQPRETSGTTGSDCQNPTDKMLSDSESQAFALTPALCKLQLAEEAQPGGAGLQSEASQAGSQETNTAEMRKVEDEEHMLTRDQTLLPRGNNKNKTNTDETKDRYSGKHRLAAISKASKRIPAKDLSPRKHVATIFSQSESESGFRRLSLYRPEDNPLSPEPTVKATESTDESSQMNVDKSETLLQETTVSSPGPPGQPCHQKSASILQPHLNGSPGVLETPPKSEGSKTQISGELGAPAQLTLTSPLEKGAGHQQRLSPPFPLEPTQKSTINSHCQLRHRSAPSPESEPEPHLYRSKSLKNFNVQSDLLCASHPPKARGRHFSENTSIDNALSQLSLEDGSFPNSGYNRRFKSSSELPASYESESWTSYSNRTRGPKSTSSISRPIDYGIFGKEQQLAFLENVKRSLTQGRLWKPSFLKNPGFLKDDVLNASNLSQSELVNSPAGQAPEDGVFPSEPLNIYKDDPVEPLVSDWDTDTTTDDEYYLDEKDKESEL 9D9864CA1396CB22 rab3a_mouse Ras-related protein Rab-3A Rab3a protein protein mouse Mus musculus Mouse MASATDSRYGQKESSDQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLTDQQAPPHQDCAC DIP protein P63011 original sequence version: 100 DIP protein P63011 original sequence version: 53 1A3E9F8C9D09EB40 sytl2_mouse Synaptotagmin-like protein 2 Sytl2 Slp2 Exophilin-4 protein protein mouse Mus musculus Mouse MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRRKKLPAAAEQNKDTAMRAKESWVNNVNKDAVLPPEIAVVEEPEDDTDPAGPSSSLVDPASSVIDMSQESTRTPAVSLPKQRKNPFNSPKLPEDHSLQQTKPEQSKTGKAGLFQISKEGELSESKEKSSIPDMPRQQLEKPKQTVSTEPENASHTKAPIPKARKLIYKSNDLEKDDNQSFPRQRRDSLNARGAPRGILKRNSSSSSTDSETLRLNYNLDPKSKILSPGLTIHERISEKEFSLEDDSSTSSLEPLKHVRFSAVKNELPQSPRPVLGQEVGEFTVLESDQLQNGTEDAGDIEEFQNHPELSHKTPLSHYQLVSSPSDSGREREQLMSSGSAPRDEIPCHSDILPTGPQCVESSSVINGQQEKSSHFTKLPSELSKSPSDELTQCGEPEPSQTADHSFRDHRQGSEEEHSPVLKTLERRAARKLPSKSLEDIPSDSSNQAKVDNLPEELVRSAEDDQKADQEPDTNECIPGISTVPSLPDNQFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFALDYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYPLKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWVEATLPLRMLLIAKLSK 226B59F5A32FA4A4 sytl1-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 2 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. Q99N80 was T7-tagged at the N-terminus. sytl2-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 11 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. Q99N50 was T7-tagged at the N-terminus. sytl3-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 5 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. Q99N48 was T7-tagged at the N-terminus. mlph-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 8 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. Q91V27 was T7-tagged at the N-terminus. slac2b-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 9 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. Q812E3 was T7-tagged at the N-terminus. sytl4-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 3 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. Q9R0Q1 was T7-tagged at the N-terminus. rph3a-rab27a-1 1 7 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 4 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association Q9ERI2 was FLAG-tagged at the N-terminus. P47708 was T7-tagged at the N-terminus. sytl4-rab3a-1 1 3 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) 10 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) physical association physical association P05713 was FLAG-tagged at the N-terminus. Q9R0Q1 was T7-tagged at the N-terminus. sytl4-rab8a-1 1 6 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) 3 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) physical association physical association P55258 was FLAG-tagged at the N-terminus. Q9R0Q1 was T7-tagged at the N-terminus. rph3a-rab3a-1 1 4 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) 10 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) physical association physical association P47708 was T7-tagged at the N-terminus. P05713 was FLAG-tagged at the N-terminus. rph3a-rab8a-1 1 4 unspecified role unspecified role prey prey ecobb Escherichia coli (strain B / BL21) 6 unspecified role unspecified role bait bait ecobb Escherichia coli (strain B / BL21) physical association physical association P55258 was FLAG-tagged at the N-terminus. P47708 was T7-tagged at the N-terminus.