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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
      <bibref>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="7671300" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5220501" refType="primary-reference" refTypeAc="MI:0358"/>
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          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA.</attribute>
            <attribute name="journal" nameAc="MI:0885">Cell (0092-8674)</attribute>
            <attribute name="publication year" nameAc="MI:0886">1995</attribute>
            <attribute name="author-list" nameAc="MI:0636">Mol CD., Arvai AS., Sanderson RJ., Slupphaug G., Kavli B., Krokan HE., Mosbaugh DW., Tainer JA.</attribute>
            <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
          </attributeList>
        </bibref>
        <xref>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
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            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Mol CD., Arvai AS., Sanderson RJ., Slupphaug G., Kavli B., Krokan HE., Mosbaugh DW., Tainer JA.</attribute>
          <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
          <attribute name="accepted"/>
          <attribute name="journal" nameAc="MI:0885">Cell (0092-8674)</attribute>
          <attribute name="publication year" nameAc="MI:0886">1995</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>ung_human</shortLabel>
          <fullName>Uracil-DNA glycosylase</fullName>
          <alias type="gene name" typeAc="MI:0301">UNG</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DGU</alias>
          <alias type="gene name synonym" typeAc="MI:0302">UNG15</alias>
          <alias type="gene name synonym" typeAc="MI:0302">UNG1</alias>
        </names>
        <xref>
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          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O00637" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O00719" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q93028" version="SP_95" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K5M6" version="SP_118" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2R8Y1" version="SP_118" refType="secondary-ac" refTypeAc="MI:0360"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003353.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_550433.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000076248" version="SP_221" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000242576" version="SP_221" refType="transcript"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VBA" version="SP_221"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110328" version="SP_221"/>
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          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24194N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGTPPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL</sequence>
        <attributeList>
          <attribute name="crc64">A4B27E6198AFE9C0</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>ungi_bppb2</shortLabel>
          <fullName>Uracil-DNA glycosylase inhibitor</fullName>
          <alias type="gene name" typeAc="MI:0301">UGI</alias>
        </names>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UDI"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UUG"/>
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        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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          <xref>
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          </xref>
        </interactorType>
        <organism ncbiTaxId="10684">
          <names>
            <shortLabel>bppb2</shortLabel>
            <fullName>Bacteriophage PBS2</fullName>
          </names>
        </organism>
        <sequence>MTNLSDIIEKETGKQLVIQESILMLPEEVEEVIGNKPESDILVHTAYDESTDENVMLLTSDAPEYKPWALVIQDSNGENKIKML</sequence>
        <attributeList>
          <attribute name="crc64">C07DCF9DB101BC2A</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>ugi-ung-1</shortLabel>
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        <experimentList>
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        <participantList>
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              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
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            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
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                  <shortLabel>region</shortLabel>
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                <featureType>
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                    <fullName>sufficient binding region</fullName>
                    <alias type="synonym" typeAc="MI:1041">sufficient to bind</alias>
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                        <fullName>certain sequence position</fullName>
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                    <begin position="3"/>
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                      </xref>
                    </endStatus>
                    <end position="84"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="1"/>
          </participant>
          <participant id="7">
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                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
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            </biologicalRole>
            <experimentalRoleList>
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                    <begin position="94"/>
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                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="313"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="1"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="assembly">dimeric, multimeric</attribute>
          <attribute name="3d-r-factors" nameAc="MI:0631">working 80.200%, free 74.500%</attribute>
          <attribute name="3d-resolution" nameAc="MI:0632">1.9A</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>