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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
      <bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
      </bibref>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
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        <secondaryRef db="pubmed" dbAc="MI:0446" id="19850723" refType="method reference" refTypeAc="MI:0357"/>
      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="15728350" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1992426" refType="identity" refTypeAc="MI:0356"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.</attribute>
            <attribute name="journal" nameAc="MI:0885">Proc. Natl. Acad. Sci. U.S.A. (0027-8424)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2005</attribute>
            <attribute name="author-list" nameAc="MI:0636">Song G., Yang Y., Liu JH., Casasnovas JM., Shimaoka M., Springer TA., Wang JH.</attribute>
            <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="15728350" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Song G., Yang Y., Liu JH., Casasnovas JM., Shimaoka M., Springer TA., Wang JH.</attribute>
          <attribute name="dataset" nameAc="MI:0875">PDBe - Data obtained from the Protein Data Bank Europe</attribute>
          <attribute name="accepted"/>
          <attribute name="journal" nameAc="MI:0885">Proc. Natl. Acad. Sci. U.S.A. (0027-8424)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2005</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>icam3_human</shortLabel>
          <fullName>Intercellular adhesion molecule 3</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">ICAM-R</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CDw50</alias>
          <alias type="gene name" typeAc="MI:0301">ICAM3</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P32942" version="SP_84" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6PD68" version="SP_96" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000160262" version="SP_206" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-725421" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002153.2"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000160262" version="SP_206" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005178" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006909" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007155" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098609" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003987" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003988" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_206"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_206"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1T0P" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198933" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-216083" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5621575" version="SP_206"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000076662" version="SP_206" refType="gene"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMGEEPSRAE</sequence>
        <attributeList>
          <attribute name="crc64">4B7BDC02F24F3031</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>ital_human</shortLabel>
          <fullName>Integrin alpha-L</fullName>
          <alias type="gene name" typeAc="MI:0301">ITGAL</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CD11A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Leukocyte adhesion glycoprotein LFA-1 alpha chain</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Leukocyte function-associated molecule 1 alpha chain</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CD11 antigen-like family member A</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P20701" version="SP_89" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000349252" version="SP_223" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43746" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q45H73" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UBC8" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3962403" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96HB1" version="SP_139" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-961214" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002200.2"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000005844" version="SP_223" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000356798" version="SP_223" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002291" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006909" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007155" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007157" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007159" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007160" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007229" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008305" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030369" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034687" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035579" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035683" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043113" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050839" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_223"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098609" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000413" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002035" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013517" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013519" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013649" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018184" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR028994" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032695" version="SP_223"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036465" version="SP_223"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1DGQ" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1IJ4" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LFA" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MJN" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MQ8" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MQ9" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MQA" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RD4" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1T0P" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XDD" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XDG" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XUO" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ZON" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ZOO" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ZOP" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ICA" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2K8O" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2M3E" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2O7N" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BN3" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BQM" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BQN" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3E2M" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EOA" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EOB" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3F74" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HI6" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3F78" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3M6F" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3TCX" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4IXD" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6R" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6S" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5E6U" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BXB" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BXF" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BXJ" version="SP_223"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CKB" version="SP_223"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198933" version="SP_223"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202733" version="SP_223"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-216083" version="SP_223"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_223"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8949275" version="SP_223"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001107852.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-623N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTYLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSESGGGKD</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P20701 original sequence version: 166</attribute>
          <attribute name="crc64">22A7AF92EF286876</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>icam3-itgal-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="rcsb pdb" dbAc="MI:0460" id="1T0P" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1041885" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041887" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>sufficient to bind</shortLabel>
                    <fullName>sufficient binding region</fullName>
                    <alias type="synonym" typeAc="MI:1041">sufficient to bind</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="153"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="326"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="1"/>
          </participant>
          <participant id="7">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="8">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-1041890" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>sufficient to bind</shortLabel>
                    <fullName>sufficient binding region</fullName>
                    <alias type="synonym" typeAc="MI:1041">sufficient to bind</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="range-conflicts">[EBI-1041891]It was impossible to shift the feature ranges when the protein sequence has been updated.</attribute>
                  <attribute name="invalid-positions">[EBI-1041891]30-115</attribute>
                  <attribute name="sequence-version">[EBI-1041891]P32942,1</attribute>
                </attributeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="10029">
                <names>
                  <shortLabel>crigr</shortLabel>
                  <fullName>Cricetulus griseus (Chinese hamster)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Cricetulus barabensis griseus</alias>
                  <alias type="synonym" typeAc="MI:1041">Chinese hamster</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="1"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="assembly">dimeric, multimeric</attribute>
          <attribute name="3d-r-factors" nameAc="MI:0631">working 78.00%, free 75.900%</attribute>
          <attribute name="3d-resolution" nameAc="MI:0632">1.66A</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>