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  <entry>
    <source releaseDate="2022-02-03">
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        <shortLabel>UniProt</shortLabel>
        <fullName>UniProt</fullName>
      </names>
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    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases.</fullName>
        </names>
        <bibref>
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            <attribute name="publication title" nameAc="MI:1091">Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nucleic Acids Res. (0305-1048)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2003</attribute>
            <attribute name="author-list" nameAc="MI:0636">Zhang Y., Woodford N., Xia X., Hamburger AW.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Chromatin - Epigenetic interactions resulting in chromatin modulation</attribute>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="4932">
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              <shortLabel>yeasx</shortLabel>
              <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
              <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
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        </hostOrganismList>
        <interactionDetectionMethod>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
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        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Zhang Y., Woodford N., Xia X., Hamburger AW.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Chromatin - Epigenetic interactions resulting in chromatin modulation</attribute>
          <attribute name="figure legend" nameAc="MI:0599">4A and B</attribute>
          <attribute name="accepted">Accepted 2006-AUG-15 by DAVET.</attribute>
          <attribute name="journal" nameAc="MI:0885">Nucleic Acids Res. (0305-1048)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2003</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>pa2g4_human</shortLabel>
          <fullName>Proliferation-associated protein 2G4</fullName>
          <alias type="gene name" typeAc="MI:0301">PA2G4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cell cycle protein p38-2G4 homolog</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ErbB3-binding protein 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">EBP1</alias>
        </names>
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          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
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        </organism>
        <sequence>MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEENEAGD</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q9UQ80 original sequence version: 148</attribute>
          <attribute name="crc64">CD45466507AD6047</attribute>
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      </interactor>
      <interactor id="3">
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          <shortLabel>hdac2_human</shortLabel>
          <fullName>Histone deacetylase 2</fullName>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7LTK" version="SP_229"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7LTL" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-193670" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2122947" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2644606" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2894862" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3214815" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-350054" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-427389" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-427413" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4551638" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804758" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-73762" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8943724" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9022692" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9022699" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9615017" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9619665" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9679191" version="SP_229"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-983231" version="SP_229"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WBZ" version="SP_229"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001518.3"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24220N"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011534090.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016866288.1"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 161</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 154</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 117</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 113</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 139</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 163</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 179</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 153</attribute>
          <attribute name="remark-internal">DIP protein Q92769 original sequence version: 112</attribute>
          <attribute name="crc64">775419CCCDAE07FA</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>pa2g4-hdac2-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-924912" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-924948" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>gst tag</shortLabel>
                    <fullName>glutathione s tranferase tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">glutathione S-tranferase tag</alias>
                    <alias type="synonym" typeAc="MI:1041">glutathione S-tranferase tag</alias>
                    <alias type="synonym" typeAc="MI:1041">gst tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0519" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456510" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
              <feature id="7">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-924950" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
                <attributeList>
                  <attribute name="invalid-range">[EBI-924951]Certain and ragged-n-terminus positions must always be strictly superior to 0 and inferior or equal to the protein sequence length. Actual positions : 395-395, sequence length 394</attribute>
                  <attribute name="invalid-positions">[EBI-924951]317-395</attribute>
                </attributeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="8">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9606">
                <names>
                  <shortLabel>human-hela</shortLabel>
                  <fullName>Homo sapiens epitheloid cervix carcinoma cells</fullName>
                  <alias type="synonym" typeAc="MI:1041">Human</alias>
                </names>
                <cellType>
                  <names>
                    <shortLabel>hela</shortLabel>
                    <fullName>Human epitheloid cervix carcinoma HeLa cells</fullName>
                  </names>
                  <xref>
                    <primaryRef db="cabri" dbAc="MI:0246" id="ACC 57" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="IA:0055" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-93029" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-300790" refType="identity" refTypeAc="MI:0356"/>
                  </xref>
                  <attributeList>
                    <attribute name="comment" nameAc="MI:0612">derivation: cervix; epithelial; adenocarcinoma</attribute>
                    <attribute name="comment" nameAc="MI:0612">ATCC no:CCL-2</attribute>
                  </attributeList>
                </cellType>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>