MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it The nuclear DICER-circular RNA complex drives the deregulation of the glioblastoma cell microRNAome. The nuclear DICER-circular RNA complex drives the deregulation of the glioblastoma cell microRNAome. Science advances 2020 imex curation Bronisz A., Rooj AK., Krawczyński K., Peruzzi P., Salińska E., Nakano I., Purow B., Chiocca EA., Godlewski J. Cancer - Interactions investigated in the context of cancer Brain Disease - Neurological Diseases & Disorders jgodlewski@bwh.harvard.edu 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-GSCs glioblastoma multiforme cancer stem cell gscs glioblastoma (multiforme) cancer stem cell =GSCs anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Bronisz A., Rooj AK., Krawczyński K., Peruzzi P., Salińska E., Nakano I., Purow B., Chiocca EA., Godlewski J. Cancer - Interactions investigated in the context of cancer jgodlewski@bwh.harvard.edu Accepted 2021-MAY-03 AT 16:01 BST AT 16:01 BST by MGT Science advances 2020 Only protein-protein interactions imex curation imex curation The nuclear DICER-circular RNA complex drives the deregulation of the glioblastoma cell microRNAome. The nuclear DICER-circular RNA complex drives the deregulation of the glioblastoma cell microRNAome. Science advances 2020 imex curation Bronisz A., Rooj AK., Krawczyński K., Peruzzi P., Salińska E., Nakano I., Purow B., Chiocca EA., Godlewski J. Cancer - Interactions investigated in the context of cancer Brain Disease - Neurological Diseases & Disorders jgodlewski@bwh.harvard.edu 24-May-2021: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-GSCs glioblastoma multiforme cancer stem cell gscs glioblastoma (multiforme) cancer stem cell =GSCs anti bait coip anti bait coimmunoprecipitation anti bait coip sequence tag sequence tag identification sequence tag Bronisz A., Rooj AK., Krawczyński K., Peruzzi P., Salińska E., Nakano I., Purow B., Chiocca EA., Godlewski J. Cancer - Interactions investigated in the context of cancer other interactors were not annotated because in the list there are a lot of obvious contaminants, so were added only those 2 interactors highlighted by the authors in figure 2E jgodlewski@bwh.harvard.edu Accepted 2021-MAY-03 AT 16:01 BST AT 16:01 BST by MGT Science advances 2020 Only protein-protein interactions imex curation imex curation rbm3_human RNA-binding protein 3 RBM3 RNPL RNA-binding motif protein 3 protein protein human Homo sapiens Human MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASVAMRAMNGESLDGRQIRVDHAGKSARGTRGGGFGAHGRGRSYSRGGGDQGYGSGRYYDSRPGGYGYGYGRSRDYNGRNQGGYDRYSGGNYRDNYDN 91C12E2A3E32CFA4 trbp2_human RISC-loading complex subunit TARBP2 Trans-activation-responsive RNA-binding protein TARBP2 TRBP TAR RNA-binding protein 2 protein protein human Homo sapiens Human MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK DIP protein Q15633 original sequence version: 71 DIP protein Q15633 original sequence version: 117 DIP protein Q15633 original sequence version: 99 DIP protein Q15633-1 original sequence version: 94 DIP protein Q15633 original sequence version: 122 768BA11751DA4912 dicer_human Endoribonuclease Dicer DICER1 DICER HERNA KIAA0928 Helicase with RNase motif protein protein human Homo sapiens Human MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRTSSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGNQLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAVMPGTTDTIQVLKGRMDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYEDDFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS 9452B96A601D4551 1-180 1 3 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 4 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 5 unspecified role unspecified role bait bait subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level association association fig. 2e 1-181 2 3 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 4 unspecified role unspecified role prey prey subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level 5 unspecified role unspecified role bait bait subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level association association fig. 2c-d; table 2s