IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. tap tandem affinity purification TAP TAP tap ms participant Identification by mass spectrometry ms participant Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer I would not call 3 or 4 tags a "tandem" tag. you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. Nuclear extracts of cells infected with either His-CBP-3XFlag-Bcor(A)-HA or ProtA2-TEV-CBP-Flag-Pcgf1 containing retroviruses;these extracts were incubated with M2-agarose (presumably anti-flag linked), eluted with Flag peptide and and recaptured with calmodulin-sepharose then stripped of associated proteins. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer No cell line is given for Supp. 6B and the authors did not respond to a request for information. you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-sudhl-4 human sudhl-4 sudhl-4 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-oci-ly7 diffuse large B-cell lymphoma-DLBCL Human oci-ly7 B-cell non-Hodgkin lymphoma cell line DSMZ no: ACC 688 ch-ip chromatin immunoprecipitation assay ch-ip q-pcr quantitative pcr q-pcr Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer Results using antibodies to H3 have not been annotated due to lack of antibody specificity. you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. Ch-IP- Re-Ch-IP: the first antibody target becomes a prey for the second antibody. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-oci-ly7 diffuse large B-cell lymphoma-DLBCL Human oci-ly7 B-cell non-Hodgkin lymphoma cell line DSMZ no: ACC 688 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-b-cell Homo sapiens B cell b-cell B-cell [B lymphocyte; B-lymphocyte; B cell; B-cells] anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. Germinal Centre B cells-B lymphocytes from the center of a lymph node (human tonsil) containing aggregations of actively proliferating lymphocytes. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions spofr-sf_9 Spodoptera frugiperda insect cells Fall armyworm sf_9 insect cells Derived from pupal ovarian tissue of the fall armyworm Cloned from the parent cell line, IPLB-SF-21-AE (SF-21) derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae cells are susceptible to Baculovirus infection anti tag coip anti tag coimmunoprecipitation anti tag coip weight by staining molecular weight estimation by staining weight by staining Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. Human proteins identified by anti-myc stain, then differentiated by molecular weight. KDM2B is stated to be a "short-form" (derived from the second promoter after the sequences encoding the JmjC domain)- but the exact isoform (of 5) is not stated so the canonical entry has been used. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-b-cell Homo sapiens B cell b-cell B-cell [B lymphocyte; B-lymphocyte; B cell; B-cells] ch-ip chromatin immunoprecipitation assay ch-ip nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer Results using antibodies to H3 have not been annotated due to lack of antibody specificity. you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. Germinal Centre B cells-B lymphocytes from the center of a lymph node (human tonsil) containing aggregations of actively proliferating lymphocytes. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-oci-ly7 diffuse large B-cell lymphoma-DLBCL Human oci-ly7 B-cell non-Hodgkin lymphoma cell line DSMZ no: ACC 688 ch-ip chromatin immunoprecipitation assay ch-ip q-pcr quantitative pcr q-pcr Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer Results using antibodies to H3 and H2A have not been annotated due to lack of antibody specificity. you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis. Cancer cell 2016 imex curation Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu 21-Mar-2017: Contacted by IntAct-Help. Only protein-protein interactions human-sudhl-6 human Human sudhl-6 Su-dhl6 B-lymphocyte ch-ip chromatin immunoprecipitation assay ch-ip q-pcr quantitative pcr q-pcr Béguelin W., Teater M., Gearhart MD., Calvo Fernández MT., Goldstein RL., Cárdenas MG., Hatzi K., Rosen M., Shen H., Corcoran CM., Hamline MY., Gascoyne RD., Levine RL., Abdel-Wahab O., Licht JD., Shaknovich R., Elemento O., Bardwell VJ., Melnick AM. Cancer - Interactions investigated in the context of cancer Results using antibodies to H3 have not been annotated due to lack of antibody specificity. you will note(?!) that the editor is leaving out the first "e" in the short label for the experiments - presumably as it has an accent on it - reported in Jira. Ch-IPs from Supp Fig 5B +S6: I have only added this figure legend to existing Chips from elsewhere in main body of publication; thus cell lines SUDHL4 andf WSU-DLCL2 results have not been added, nor all results from OCI-Ly7. Fig S5 results for SUDHL6 do NOT include any for CDKN1B - which is the only gene already entered for this cell line. amm2014@med.cornell.edu,bardw001@umn.edu Accepted 2016-DEC-13 AT 14:03 GMT AT 14:03 GMT by ORCHARD Cancer cell 2016 imex curation I have added a comment to EBI-12552979, as well as deleting CBX8. cbx4_human E3 SUMO-protein ligase CBX4 Chromobox protein homolog 4 Polycomb 2 homolog CBX4 protein protein human Homo sapiens Human MELPAVGEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTDNRAKLDLGAQGKGQGHQYELNSKKHHQYQPHSKERAGKPPPPGKSGKYYYQLNSKKHHPYQPDPKMYDLQYQGGHKEAPSPTCPDLGAKSHPPDKWAQGAGAKGYLGAVKPLAGAAGAPGKGSEKGPPNGMMPAPKEAVTGNGIGGKMKIVKNKNKNGRIVIVMSKYMENGMQAVKIKSGEVAEGEARSPSHKKRAADERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLSHVRKRCLSETHGEREPCKKRLTARSISTPTCLGGSPAAERPADLPPAAALPQPEVILLDSDLDEPIDLRCVKTRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV DF5C8C4C0CCB1F31 otud4_human OTU domain-containing protein 4 HIN-1 HIV-1-induced protein HIN-1 OTUD4 KIAA1046 protein protein human Homo sapiens Human MEAAVGVPDGGDQGGAGPREDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIVMELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHRNVRGRPFRGDRRRSGMGDGHRGQHT AD8DF5FEAB8CBE32 gptc4_human G patch domain-containing protein 4 GPATCH4 GPATC4 protein protein human Homo sapiens Human MNVTPEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTHGVGHDPAKEFTNHWWNELFNKTAANLVVETGQDGVQIRSLSKETTRYNHPKPNLLYQKFVKMATLTSGGEKPNKDLESCSDDDNQGSKSPKILTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLARLKGQDPGAPQLQSESKPPKKKKKKRRQKEEEEATASERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKKRQQQEEEDLNLEDRGEETVLGGGTREAESRACSDGRSRKSKKKRQQHQEEEDILDVRDEKDGGAREAESRAHTGSSSRGKRKRQQHPKKERAGVSTVQKAKKKQKKRD 51D64BF5B4AEB3C6 ylpm1_human YLP motif-containing protein 1 Nuclear protein ZAP3 ZAP113 YLPM1 C14orf170 ZAP3 protein protein human Homo sapiens Human MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI DIP protein P49750 original sequence version: 122 2C8F694D43061047 dpy30_human Protein dpy-30 homolog DPY30 Dpy-30-like protein protein protein human Homo sapiens Human MEPEQMLEGQTQVAENPHSEYGLTDNVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFEDRN DIP protein Q9C005 original sequence version: 65 DIP protein Q9C005 original sequence version: 93 DIP protein Q9C005 original sequence version: 106 DIP protein Q9C005 original sequence version: 79 5356AC515B9C2ADB zn326_human DBIRD complex subunit ZNF326 ZNF326 ZIRD Zinc finger protein 326 Zinc finger protein interacting with mRNPs and DBC1 protein protein human Homo sapiens Human MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRKMMQPFNKPSGTFIKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVMEFLHECMVNKFKKTSIRKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSSVQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 7F513DA0C5B7F3CD pcgf1_human Polycomb group RING finger protein 1 RING finger protein 68 Nervous system Polycomb-1 PCGF1 NSPC1 RNF68 protein protein human Homo sapiens Human MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVKEKRR 456C9417E53A01B6 abcb7_human Iron-sulfur clusters transporter ABCB7, mitochondrial ABCB7 ABC7 ATP-binding cassette transporter 7 ATP-binding cassette sub-family B member 7, mitochondrial protein protein human Homo sapiens Human MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQIPESLKSITWQRLGKGNSGQFLDAAKALQVWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMASPLQITPQTATVAFDNVHFEYIEGQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKWEAKKENISKEEERKKLQEEIVNSVKGCGNCSC B1FFA57ABD24FB90 ubp2l_human Ubiquitin-associated protein 2-like UBAP2L Protein NICE-4 KIAA0144 NICE4 protein protein human Homo sapiens Human MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTSAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSTMENDSSNLDPSQAPSLAQPLVFSNSKQTAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN FED18847387AA1F5 setd4_human SET domain-containing protein 4 SETD4 C21orf18 C21orf27 protein protein human Homo sapiens Human MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSLQPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSREILVKYLPSTDKQMDKKISILKDHGYIENLTFGWDGPSWRLLTALKLLCLEAEKFTCWKKVLLGEVISDTNEKTSLDIAQKICYYFIEETNAVLQKVSHMKDEKEALINQLTLVESLWTEELKILRASAETLHSLQTAFT 9EBCAA05397BE287 bcor_human BCL-6 corepressor BCOR KIAA1575 protein protein human Homo sapiens Human MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTNGERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVPTDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKPSVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPFLEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAMMRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW A80CFCD5618EE717 ari3b_human_gene AT-rich interactive domain-containing protein 3B ARID3B BDP DRIL2 gene gene human Homo sapiens Human morc4_human MORC family CW-type zinc finger protein 4 MORC4 ZCWCC2 Zinc finger CW-type coiled-coil domain protein 2 ZCW4 Zinc finger CW-type domain protein 4 protein protein human Homo sapiens Human MLLYRGAPAGPGAPGCGLARPGGGPQAFGIRLSTMSPRYLQSNSSSHTRPFSAIAELLDNAVDPDVSARTVFIDVEEVKNKSCLTFTDDGCGMTPHKLHRMLSFGFTDKVIKKSQCPIGVFGNGFKSGSMRLGKDALVFTKNGGTLTVGLLSQTYLECVQAQAVIVPIVPFNQQNKKMIITEDSLPSLEAILNYSIFNRENDLLAQFDAIPGKKGTRVLIWNIRRNKNGKSELDFDTDQYDILVSDFDTEEKMTGGVTSELPETEYSLRAFCGILYMKPRMKIFLRQKKVTTQMIAKSLANVEYDTYKPTFTNKQVRITFGFSCKNSNQFGIMMYHNNRLIKSFEKVGCQVKPTRGEGVGVIGVIECNFLKPAYNKQDFEYTKEYRLTINALAQKLNAYWKEKTSQDNFETSTVARPIPKVPDQTWVQCDECLKWRKLPGKIDPSMLPARWFCYYNSHPKYRRCSVPEEQELTDEDLCLSKAKKQEQTVEEKKKMPMENENHQVFSNPPKILTVQEMAGLNNKTIGYEGIHSPSVLPSGGEESRSPSLQLKPLDSSVLQFSSKYKWILGEEPVEKRRRLQNEMTTPSLDYSMPAPYRRVEAPVAYPEGENSHDKSSSERSTPPYLFPEYPEASKNTGQNREVSILYPGAKDQRQGSLLPEELEDQMPRLVAEESNRGSTTINKEEVNKGPFVAVVGVAKGVRDSGAPIQLIPFNREELAERRKAVESWNPVPYSVASAAIPAAAIGEKARGYEESEGHNTPKLKNQRELEELKRTTEKLERVLAERNLFQQKVEELEQERNHWQSEFKKVQHELVIYSTQEAEGLYWSKKHMGYRQAEFQILKAELERTKEEKQELKEKLKETETHLEMLQKAQVSYRTPEGDDLERALAKLTRLRIHVSYLLTSVLPHLELREIGYDSEQVDGILYTVLEANHILD 7AABDA01596475D2 qser1_human Glutamine and serine-rich protein 1 QSER1 protein protein human Homo sapiens Human MNFLSTAESRTAQAAASGTTLLPQFRAPSWQTGMHSSAATELFATGPLPSTGTLPPSLSAYQHPTTFSNRNFATTSPLVLQDSTFNTTSNGILSHHDPLLQIKTSQGTVPTALAFERLGSSVLSNSIPPQSSTYRSAQESAPHLLQPQFSLLPSALGGSQQTPQAYSSTLFTSSTASIERALLRECSVIKHHQRPSGTQSIQAQLTGSQHSLHSYLSNSSVVNFQETTRQSSLSCSPIGDSTQVSNGGLQQKTSQVSVELAQSYSSAIPSSGYPPSTTKIKSCSTEQPLTSTKTPKPQSIIPPVQTLSYSKPLHNQSSVISGQAQIYSTAQLPSLLSVSQSQNYGLVQPHNVPSIVHSQVYRSSKVEKLPPLYKTLTFSGSSQTVTPENQTLNYSSNQQEVLSSVTNENYPAQTRDLSSVSQSQSYSSGHSQGLSPVSQTQVSYSSQSQVLSVVSLSESYASGESLTLTAPSLSYSSASRAQNLPDSSPTQNYISMHSSQNVQTQESSSPQSQKFLPAVQSSSFASSTHCQTLQNNITSPDPKSYAERKLDSDVYPSSKQEDGFPMQELQVLQPQASLESSTQRLSDGEINAQESTYKVSKADDRYSQSVIRSNSRLEDQVIGVALQASKKEESVVGSVTQLNQQIGQVNNAATLDLKNSTNLIQTPQIRLNTKDLKQQHPLILKVHESKVQEQHDQIINASSQIQIPNHALGHGHQASLPNTQVLLDSACDLQILQQSILQAGLGQVKASLQAQRVQSPQQIVHPFLQMEGHVIQSNGDHSQQQLHPQNSEVMKMDLSESSKPLQQHLTTKGHFSETNQHDSKNQFVSLGSMCFPEAVLLSDERNILSNVDDILAATAAACGVTPTDFSKSTSNETMQAVEDGDSKSHFQQSLDVRHVTSDFNSMTATVGKPQNINDTSLNGNQVTVNLSPVPALQSKMTLDQQHIETPGQNIPTKVTSAVVGPSHEVQEQSSGPFKKQSATNLESEEDSEAPVDSTLNNNRNQEFVSSSRSISGENATSESEFTLGGDDSGVSMNPARSALALLAMAQSGDAVSVKIEEENQDLMHFNLQKKRAKGKGQVKEEDNSNQKQLKRPAQGKRQNPRGTDIYLPYTPPSSESCHDGYQHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPKQQFSTLAVRMPNRTRRPGTQMVRTFCPPPLPKPSSTTPTPLVSETGGNSPSDKVDNELKNLEHLSSFSSDEDDPGYSQDAYKSVSTPLTTLDATSDKKKKTEALQVATTSPTANTTGTATTSSTTVGAVKQEPLHSTSYAVNILENISSSESSKPIELDGLPSDQFAKGQDTVAIEGFTDEEDTESGGEGQYRERDEFVVKIEDIETFKEALKTGKEPPAIWKVQKALLQKFVPEIRDGQREFAATNSYLGYFGDAKSKYKRIYVKFIENANKKEYVRVCSKKPRNKPSQTIRTVQAKPSSSSKTSDPLASKTTTTKAPSVKPKVKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEIHTSSSDDEEFEPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLLNLHLDQSFKNALESFPELTIITRDSKAKSGGTAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSLYHSLHHYKYHVYLICKDEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQQKCS 9FC28818DBB42A92 ring1_human E3 ubiquitin-protein ligase RING1 RING finger protein 1 Polycomb complex protein RING1 RING1 RNF1 Really interesting new gene 1 protein RING-type E3 ubiquitin transferase RING1 protein protein human Homo sapiens Human MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK DIP protein Q06587 original sequence version: 103 DIP protein Q06587 original sequence version: 147 DIP protein Q06587 original sequence version: 135 6959787479DE9DAB cdkn1b_human_gene Cyclin-dependent kinase inhibitor 1B (p27Kip1) gene gene human Homo sapiens Human nop56_human Nucleolar protein 56 NOP56 NOL5A Nucleolar protein 5A protein protein human Homo sapiens Human MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKKKKVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED 17D81E25DEBD052F bmi1_human_gene Polycomb complex protein BMI-1 BMI1 PCGF4 RNF51 gene gene human Homo sapiens Human ezh2_human Histone-lysine N-methyltransferase EZH2 KMT6 Enhancer of zeste homolog 2 ENX-1 Lysine N-methyltransferase 6 EZH2 protein protein human Homo sapiens Human MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP DIP protein Q15910 original sequence version: 97 DIP protein Q15910 original sequence version: 94 DIP protein Q15910 original sequence version: 92 DIP protein Q15910 original sequence version: 96 DIP protein Q15910 original sequence version: 122 DIP protein Q15910 original sequence version: 100 1B5029EB9D509BE5 ari3a_human_gene AT-rich interactive domain-containing protein 3A ARID3A DRIL1 DRIL3 DRX E2FBP1 gene gene human Homo sapiens Human zn281_human Zinc finger protein 281 ZNF281 GZP1 ZBP99 Zinc finger DNA-binding protein 99 Transcription factor ZBP-99 GC-box-binding zinc finger protein 1 protein protein human Homo sapiens Human MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEPTFPQGMVMFNHRLPPVTSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGGEGGSHGVIQDLSILHQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNVKKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHLRRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEVIVKGATSAEPGSSNHTNMGNLAVLSQGNTSSSRRKTKSKSIAIENKEQKTGKTNESQISNNINMQSYSVEMPTVSSSGGIIGTGIDELQKRVPKLIFKKGSRKNTDKNYLNFVSPLPDIVGQKSLSGKPSGSLGIVSNNSVETIGLLQSTSGKQGQISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKEDPFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNASFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQKNLESSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR 556FAAEA8D095FB7 sugp2_human SURP and G-patch domain-containing protein 2 Arginine/serine-rich-splicing factor 14 SUGP2 KIAA0365 SFRS14 Splicing factor, arginine/serine-rich 14 protein protein human Homo sapiens Human MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRANK 619AE0AC087761BD enl_human Protein ENL MLLT1 ENL LTG19 YEATS1 YEATS domain-containing protein 1 protein protein human Homo sapiens Human MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT A8480BA0F8742173 fras1_human Extracellular matrix organizing protein FRAS1 Fraser syndrome 1 protein FRAS1 KIAA1500 protein protein human Homo sapiens Human MGVLKVWLGLALALAEFAVLPHHSEGACVYQDSLLADATIWKPDSCQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKSPHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQDSGLCKNCDSYCLQCQGPHECTRCKGPFLLLEAQCVQECGKGYFADHAKHKCTACPQGCLQCSHRDRCHLCDHGFFLKSGLCVYNCVPGFSVHTSNETCSGKIHTPSLHVNGSLILPIGSIKPLDFSLLNVQDQEGRVEDLLFHVVSTPTNGQLVLSRNGKEVQLDKAGRFSWKDVNEKKVRFVHSKEKLRKGYLFLKISDQQFFSEPQLINIQAFSTQAPYVLRNEVLHISRGERATITTQMLDIRDDDNPQDVVIEIIDPPLHGQLLQTLQSPATPIYQFQLDELSRGLLHYAHDGSDSTSDVAVLQANDGHSFHNILFQVKTVPQNDRGLQLVANSMVWVPEGGMLQITNRILQAEAPGASAEEIIYKITQDYPQFGEVVLLVNMPADSPADEGQHLPDGRTATPTSTFTQQDINEGIVWYRHSGAPAQSDSFRFEVSSASNAQTRLESHMFNIAILPQTPEAPKVSLEASLHMTAREDGLTVIQPHSLSFINSEKPSGKIVYNITLPLHPNQGIIEHRDHPHSPIRYFTQEDINQGKVMYRPPPAAPHLQELMAFSFAGLPESVKFHFTVSDGEHTSPEMVLTIHLLPSDQQLPVFQVTAPRLAVSPGGSTSVGLQVVVRDAETAPKELFFELRRPPQHGVLLKHTAEFRRPMATGDTFTYEDVEKNALQYIHDGSSTREDSMEISVTDGLTVTMLEVRVEVSLSEDRGPRLAAGSSLSITVASKSTAIITRSHLAYVDDSSPDPEIWIQLNYLPSYGTLLRISGSEVEELSEVSNFTMEDINNKKIRYSAVFETDGHLVTDSFYFSVSDMDHNHLDNQIFTIMITPAENPPPVIAFADLITVDEGGRAPLSFHHFFATDDDDNLQRDAIIKLSALPKYGCIENTGTGDRFGPETASDLEASFPIQDVLENYIYYFQSVHESIEPTHDIFSFYVSDGTSRSEIHSINITIERKNDEPPRMTLQPLRVQLSSGVVISNSSLSLQDLDTPDNELIFVLTKKPDHGHVLWRQTASEPLENGRVLVQGSTFTYQDILAGLVGYVPSVPGMVVDEFQFSLTDGLHVDTGRMKIYTELPASDTPHLAINQGLQLSAGSVARITEQHLKVTDIDSDDHQVMYIMKEDPGAGRLQMMKHGNLEQISIKGPIRSFTQADISQGQPEYSHGTGEPGGSFAFKFDVVDGEGNRLIDKSFSISISEDKSPPVITTNKGLVLDENSVKKITTLQLSATDQDSGPTELIYRITRQPQLGHLEHAASPGIQISSFTQADLTSRNVQYVHSSEAEKHSDAFSFTLSDGVSEVTQTFHITLHPVDDSLPVVQNLGMRVQEGMRKTITEFELKAVDADTEAESVTFTIVQPPRHGTIERTSNGQHFHLTSTFTMKDIYQNRVSYSHDGSNSLKDRFTFTVSDGTNPFFIIEEGGKEIMTAAPQPFRVDILPVDDGTPRIVTNLGLQWLEYMDGKATNLITKKELLTMDPDTEDAQLVYEITTGPKHGFVENKLQPGRAAATFTQEDVNLGLIRYVLHKEKIREMMDSFQFLVKDSKPNVVSDNVFHIQWSLISFKYTSYNVSEKAGSVSVTVQRTGNLNQYAIVLCRTEQGTASSSSQPGQQDYVEYAGQVQFDEREDTKSCTIVINDDDVFENVESFTVELSMPAYALLGEFTQAKVIINDTEDEPTLEFDKKIYWVNESAGFLFAPIERKGDASSIVSAICYTVPKSAMGSLFYALESGSDFKSRGMSAASRVIFGPGVTMSTCDVMLIDDSEYEEEEEFEIALADASDNARIGRVATAKVLISGPNDASTVSLGNTAFTVSEDAGTVKIPVIRHGTDLSTFASVWCATRPSDPASATPGVDYVPSSRKVEFGPGVIEQYCTLTILDDTQYPVIEGLETFVVFLSSAQGAELTKPFQAVIAINDTFQDVPSMQFAKDLLLVKEKEGVLHVPITRSGDLSYESSVRCYTQSHSAQVMEDFEERQNADSSRITFLKGDKVKNCTVYIHDDSMFEPEEQFRVYLGLPLGNHWSGARIGKNNMATITISNDEDAPTIEFEEAAYQVREPAGPDAIAILNIKVIRRGDQNRTSKVRCSTRDGSAQSGVDYYPKSRVLKFSPGVDHIFFKVEILSNEDREWHESFSLVLGPDDPVEAVLGDVTTATVTILDQEAAGSLILPAPPIVVTLADYDHVEEVTKEGVKKSPSPGYPLVCVTPCDPHFPRYAVMKERCSEAGINQTSVQFSWEVAAPTDGNGARSPFETITDNTPFTSVNHMVLDSIYFSRRFHVRCVAKAVDKVGHVGTPLRSNIVTIGTDSAICHTPVVAGTSRGFQAQSFIATLKYLDVKHKEHPNRIHISVQIPHQDGMLPLISTMPLHNLHFLLSESIYRHQHVCSNLVTTYDLRGLAEAGFLDDVVYDSTALGPGYDRPFQFDPSVREPKTIQLYKHLNLKSCVWTFDAYYDMTELIDVCGGSVTADFQVRDSAQSFLTVHVPLYVSYIYVTAPRGWASLEHHTEMEFSFFYDTVLWRTGIQTDSVLSARLQIIRIYIREDGRLVIEFKTHAKFRGQFVMEHHTLPEVKSFVLTPDHLGGIEFDLQLLWSAQTFDSPHQLWRATSSYNRKDYSGEYTIYLIPCTVQPTQPWVDPGEKPLACTAHAPERFLIPIAFQQTNRPVPVVYSLNTEFQLCNNEKVFLMDPNTSDMSLAEMDYKGAFSKGQILYGRVLWNPEQNLNSAYKLQLEKVYLCTGKDGYVPFFDPTGTIYNEGPQYGCIQPNKHLKHRFLLLDRNQPEVTDKYFHDVPFEAHFASELPDFHVVSNMPGVDGFTLKVDALYKVEAGHQWYLQVIYIIGPDTISGPRVQRSLTAPLRRNRRDLVEPDGQLILDDSLIYDNEGDQVKNGTNMKSLNLEMQELAVAASLSQTGASIGSALAAIMLLLLVFLVACFINRKCQKQRKKKPAEDILEEYPLNTKVEVPKRHPDRVEKNVNRHYCTVRNVNILSEPEAAYTFKGAKVKRLNLEVRVHNNLQDGTEV mint Defects in FRAS1 are a cause of Fraser syndrome [MIM:219000]. It is a multisystem malformation usually comprising cryptophthalmos, cutaneous syndactyly, ear abnormalities, renal agenesis and congenital heart defects 79972020FA59C3CD suz12_human Polycomb protein SUZ12 CHET9 JJAZ1 KIAA0160 SUZ12 Suppressor of zeste 12 protein homolog Joined to JAZF1 protein Chromatin precipitated E2F target 9 protein protein protein human Homo sapiens Human MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL DIP protein Q15022 original sequence version: 92 DIP protein Q15022 original sequence version: 88 DIP protein Q15022 original sequence version: 91 DIP protein Q15022 original sequence version: 106 A8830EBC3FD38D56 kdm2b_human Lysine-specific demethylase 2B KDM2B CXXC2 FBL10 FBXL10 JHDM1B PCCX2 CXXC-type zinc finger protein 2 F-box and leucine-rich repeat protein 10 F-box protein FBL10 F-box/LRR-repeat protein 10 JmjC domain-containing histone demethylation protein 1B Jumonji domain-containing EMSY-interactor methyltransferase motif protein Protein-containing CXXC domain 2 [Histone-H3]-lysine-36 demethylase 1B NDY1 protein protein human Homo sapiens Human MAGPQMGGSAEDHPPRKRHAAEKQKKKTVIYTKCFEFESATQRPIDRQRYDENEDLSDVEEIVSVRGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDFTVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHTKLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFTDFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQRIELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFRYPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEEACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKGKLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIKESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQEPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRASSLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAEDRMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKMRRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICERPHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPPPDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQFGQVEEKLLQKLS cbx8_human Chromobox protein homolog 8 Polycomb 3 homolog Rectachrome 1 CBX8 PC3 RC1 protein protein human Homo sapiens Human MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRAREGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGKFPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR DIP protein Q9HC52 original sequence version: 81 DIP protein Q9HC52 original sequence version: 80 DIP protein Q9HC52 original sequence version: 102 DIP protein Q9HC52 original sequence version: 107 651263C85B0ECD93 emsy_human BRCA2-interacting transcriptional repressor EMSY EMSY C11orf30 GL002 protein protein human Homo sapiens Human MPVVWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVRRAVNDERLTTIAHNMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTTSPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTPSPIPNTVAVTAVVSSTPSVVMSTVAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQESGVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPTVSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTSKPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMIVTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSSESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESELVAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQRTLLQHVAQSQTATQTSVVVKSIPASSPGAITHIMQQALSSHTAFTKHSEELGTEEGEVEEMDTLDPQTGLFYRSALTQSQSAKQQKLSQPPLEQTQLQVKTLQCFQTKQKQTIHLQADQLQHKLPQMPQLSIRHQKLTPLQQEQAQPKPDVQHTQHPMVAKDRQLPTLMAQPPQTVVQVLAVKTTQQLPKLQQAPNQPKIYVQPQTPQSQMSLPASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS DIP protein Q7Z589 original sequence version: 38 7F8C95E8BA0FC9F0 zch18_human Zinc finger CCCH domain-containing protein 18 NHN1 Nuclear protein NHN1 ZC3H18 protein protein human Homo sapiens Human MDVAESPERDPHSPEDEEQPQGLSDDDILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEIDDGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHPGVNDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDTVLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERERERERERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIPGKA F12E87B342E1F892 zfr_human Zinc finger RNA-binding protein ZFR M-phase phosphoprotein homolog protein protein human Homo sapiens Human MIPICPVVSFTYVPSRLGEDAKMATGNYFGFTHSGAAAAAAAAQYSQQPASGVAYSHPTTVASYTVHQAPVAAHTVTAAYAPAAATVAVARPAPVAVAAAATAAAYGGYPTAHTATDYGYTQRQQEAPPPPPPATTQNYQDSYSYVRSTAPAVAYDSKQYYQQPTATAAAVAAAAQPQPSVAETYYQTAPKAGYSQGATQYTQAQQTRQVTAIKPATPSPATTTFSIYPVSSTVQPVAAAATVVPSYTQSATYSTTAVTYSGTSYSGYEAAVYSAASSYYQQQQQQQKQAAAAAAAAAATAAWTGTTFTKKAPFQNKQLKPKQPPKPPQIHYCDVCKISCAGPQTYKEHLEGQKHKKKEAALKASQNTSSSNSSTRGTQNQLRCELCDVSCTGADAYAAHIRGAKHQKVVKLHTKLGKPIPSTEPNVVSQATSSTAVSASKPTASPSSIAANNCTVNTSSVATSSMKGLTTTGNSSLNSTSNTKVSAVPTNMAAKKTSTPKINFVGGNKLQSTGNKAEDIKGTECVKSTPVTSAVQIPEVKQDTVSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGKVIRFHCKLCECSFNDPNAKEMHLKGRRHRLQYKKKVNPDLQVEVKPSIRARKIQEEKMRKQMQKEEYWRRREEEERWRMEMRRYEEDMYWRRMEEEQHHWDDRRRMPDGGYPHGPPGPLGLLGVRPGMPPQPQGPAPLRRPDSSDDRYVMTKHATIYPTEEELQAVQKIVSITERALKLVSDSLSEHEKNKNKEGDDKKEGGKDRALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKTLLSRIAENLPKQLAVISPEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFPSWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAFRQIHKVLGMDPLPQMSQRFNIHNNRKRRRDSDGVDGFEAEGKKDKKDYDNF 3E43654E7134E9FC hnrpf_human Heterogeneous nuclear ribonucleoprotein F HNRNPF HNRPF Nucleolin-like protein mcs94-1 protein protein human Homo sapiens Human MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRPGAYSTGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD DIP protein P52597 original sequence version: 152 D14E170631FB1F31 ctcf_human Transcriptional repressor CTCF CCCTC-binding factor CTCFL paralog 11-zinc finger protein CTCF protein protein human Homo sapiens Human MEGDAVEAIVEESETFIKGKERKTYQRRREGGQEEDACHLPQNQTDGGEVVQDVNSSVQMVMMEQLDPTLLQMKTEVMEGTVAPEAEAAVDDTQIITLQVVNMEEQPINIGELQLVQVPVPVTVPVATTSVEELQGAYENEVSKEGLAESEPMICHTLPLPEGFQVVKVGANGEVETLEQGELPPQEDPSWQKDPDYQPPAKKTKKTKKSKLRYTEEGKDVDVSVYDFEEEQQEGLLSEVNAEKVVGNMKPPKPTKIKKKGVKKTFQCELCSYTCPRRSNLDRHMKSHTDERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVCSKCGKTFTRRNTMARHADNCAGPDGVEGENGGETKKSKRGRKRKMRSKKEDSSDSENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRPPGRTNQPKQNQPTAIIQVEDQNTGAIENIIVEVKKEPDAEPAEGEEEEAQPAATDAPNGDLTPEMILSMMDR DIP protein P49711 original sequence version: 116 2110538B65DC5706 rbbp4_human Histone-binding protein RBBP4 Retinoblastoma-binding protein 4 Retinoblastoma-binding protein p48 Chromatin assembly factor 1 subunit C Chromatin assembly factor I p48 subunit Nucleosome-remodeling factor subunit RBAP48 RBBP4 RBAP48 protein protein human Homo sapiens Human MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS DIP protein Q09028 original sequence version: 151 DIP protein Q09028 original sequence version: 111 DIP protein Q09028 original sequence version: 116 DIP protein Q09028-1 original sequence version: 130 DIP protein Q09028 original sequence version: 149 DIP protein Q09028 original sequence version: 159 DIP protein Q09028 original sequence version: 131 B71E2D55A444C360 fubp3_human Far upstream element-binding protein 3 FUBP3 FBP3 protein protein human Homo sapiens Human MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSPPDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ F1BE223542BC197D nop58_human Nucleolar protein 58 NOP58 NOL5 Nucleolar protein 5 NOP5 HSPC120 protein protein human Homo sapiens Human MLVLFETSVGYAIFKVLNEKKLQEVDSLWKEFETPEKANKIVKLKHFEKFQDTAEALAAFTALMEGKINKQLKKVLKKIVKEAHEPLAVADAKLGGVIKEKLNLSCIHSPVVNELMRGIRSQMDGLIPGVEPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWHFPELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNLAKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVLAIRYDAFGEDSSSAMGVENRAKLEARLRTLEDRGIRKISGTGKALAKTEKYEHKSEVKTYDPSGDSTLPTCSKKRKIEQVDKEDEITEKKAKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSEEEPCTSTAIASPEKKKKKKKKRENED DIP protein Q9Y2X3 original sequence version: 137 27CD73CFF5B9A556 yaf2_human YY1-associated factor 2 YAF2 protein protein human Homo sapiens Human MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDKVEKEKSEKETTSKKNSHKKTRPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPASSAASADQHSQSGSSSDNTERGMSRSSSPRGEASSLNGESH 199A56EE06BB4FBE cdkn1a_human_gene Human CDKN1A gene gene gene human Homo sapiens Human zn148_human Zinc finger protein 148 ZBP89 Transcription factor ZBP-89 Zinc finger DNA-binding protein 89 ZNF148 protein protein human Homo sapiens Human MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQDSVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESALDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG 50413723459EBD1F eed_human Polycomb protein EED EED WD protein associating with integrin cytoplasmic tails 1 Embryonic ectoderm development protein protein protein human Homo sapiens Human MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR DIP protein O75530 original sequence version: 70 DIP protein O75530-1 original sequence version: 78 DIP protein O75530 original sequence version: 78 DIP protein O75530 original sequence version: 73 DIP protein O75530-1 original sequence version: 89 DIP protein O75530-1 original sequence version: 87 DIP protein O75530 original sequence version: 77 D2E0A5BA27C0499A amot_human Angiomotin AMOT KIAA1071 protein protein human Homo sapiens Human MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNGPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARPAQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMVEYLI DIP protein Q4VCS5 original sequence version: 101 D7E7021E9535A628 prdm1_human_gene PR domain zinc finger protein 1 (PRDM1) human gene gene gene human Homo sapiens Human rfox2_human RNA binding protein fox-1 homolog 2 FOX2 RNA-binding motif protein 9 Fox-1 homolog B Hexaribonucleotide-binding protein 2 Repressor of tamoxifen transcriptional activity RBFOX2 HRNBP2 RTA RBM9 RNA-binding protein 9 protein protein human Homo sapiens Human MQNEPLTPGYHGFPARDSQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNDAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY 40D6C8C40764B317 ccar2_human Cell cycle and apoptosis regulator protein 2 CCAR2 Cell division cycle and apoptosis regulator protein 2 DBC1 DBIRD complex subunit KIAA1967 Deleted in breast cancer gene 1 protein KIAA1967 p30 DBC NET35 protein protein human Homo sapiens Human MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITADSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQTVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPAPSN DIP protein Q8N163 original sequence version: 96 DIP protein Q8N163 original sequence version: 139 1733934377E35D21 zn512_human Zinc finger protein 512 ZNF512 KIAA1805 protein protein human Homo sapiens Human MSSRLGAVPATSGPTTFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSHVEGSGGVSAKGKRKPRQEEDEDYREFPQKKHKLYGRKQRPKTQPNPKSQARRIRKEPPVYAAGSLEEQWYLEIVDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLRSLAGMKYHVMANHNSLPILKAGDEIDEPSERERLRTVLKRLGKLRCMRESCSSSFTSIMGYLYHVRKCGKGAAELEKMTLKCHHCGKPYRSKAGLAYHLRSEHGPISFFPESGQPECLKEMNLESKSGGRVQRRSAKIAVYHLQELASAELAKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKRRQQHRSRRSLRRRQQPGIELPETELSLRVGKDQRRNNEELVVSASCKEPEQEPVPAQFQKVKPPKTNHKRGRK 0837E9DB4ED46E75 foxc1_human Forkhead box protein C1 Forkhead-related protein FKHL7 Forkhead-related transcription factor 3 FOXC1 FKHL7 FREAC3 protein protein human Homo sapiens Human MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF 59C6FB94303ED59A bcorl_human BCL-6 corepressor-like protein 1 BCORL1 protein protein human Homo sapiens Human MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQAEVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS DD78A00598703C53 af9_human Protein AF-9 ALL1-fused gene from chromosome 9 protein Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein YEATS domain-containing protein 3 MLLT3 AF9 YEATS3 protein protein human Homo sapiens Human MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS DIP protein P42568 original sequence version: 135 DIP protein P42568 original sequence version: 103 DIP protein P42568 original sequence version: 136 0A020B7FB34132F9 bcl6_human B-cell lymphoma 6 protein Zinc finger protein 51 Protein LAZ-3 B-cell lymphoma 5 protein Zinc finger and BTB domain-containing protein 27 BCL6 BCL5 LAZ3 ZBTB27 ZNF51 protein protein human Homo sapiens Human MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDTCRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAFAPSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPGEYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC DIP protein P41182 original sequence version: 121 DIP protein P41182 original sequence version: 127 E38D83C213DAE2D0 ring2_human E3 ubiquitin-protein ligase RING2 RING finger protein 2 RING finger protein 1B RING finger protein BAP-1 Protein DinG Huntingtin-interacting protein 2-interacting protein 3 RNF2 BAP1 DING HIPI3 RING1B RING-type E3 ubiquitin transferase RING2 protein protein human Homo sapiens Human MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK DIP protein Q99496 original sequence version: 95 DIP protein Q99496 original sequence version: 94 DIP protein Q99496 original sequence version: 96 DIP protein Q99496 original sequence version: 125 DIP protein Q99496 original sequence version: 142 DIP protein Q99496 original sequence version: 159 DIP protein Q99496 original sequence version: 129 DIP protein Q99496 original sequence version: 99 DIP protein Q99496 original sequence version: 118 90EA546E1F4DB7EC msi1h_human RNA-binding protein Musashi homolog 1 MSI1 protein protein human Homo sapiens Human METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH 26487B0A32CF1F40 irf4_human_gene Interferon regulatory factor 4 IRF4 MUM1 gene gene human Homo sapiens Human mkrn2_human Probable E3 ubiquitin-protein ligase makorin-2 MKRN2 RNF62 RING finger protein 62 HSPC070 RING-type E3 ubiquitin transferase makorin-2 protein protein human Homo sapiens Human MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP 1F1564E589EB6632 cyfp1_human Cytoplasmic FMR1-interacting protein 1 Specifically Rac1-associated protein 1 p140sra-1 CYFIP1 KIAA0068 protein protein human Homo sapiens Human MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRFESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVPLKKMVERIRKFQILNDEIITILDKYLKSGDGEGTPVEHVRCFQPPIHQSLASS DIP protein Q7L576 original sequence version: 55 DIP protein Q7L576-1 original sequence version: 59 DIP protein Q7L576 original sequence version: 59 DIP protein Q7L576 original sequence version: 100 D8F45E13207BEF16 skp1_human S-phase kinase-associated protein 1 SKP1 EMC19 OCP2 SKP1A TCEB1L Cyclin-A/CDK2-associated protein p19 p19skp1 RNA polymerase II elongation factor-like protein Organ of Corti protein 2 Organ of Corti protein II SIII Transcription elongation factor B polypeptide 1-like protein protein human Homo sapiens Human MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK C794D62AFB75528A rybp_human RING1 and YY1-binding protein Death effector domain-associated factor YY1 and E4TF1-associated factor 1 Apoptin-associating protein 1 RYBP DEDAF YEAF1 protein protein human Homo sapiens Human MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF DIP protein Q8N488 original sequence version: 70 DIP protein Q8N488 original sequence version: 110 EB9593460A3F0F4C bcl6-cdkn1b_human_gene-1 8 26 unspecified role unspecified role prey prey proximal_promoter_plus_exon1+2, intron1+partial_intron2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait association association 3D bcl6-bcor-2 8 58 unspecified role unspecified role bait bait 26 unspecified role unspecified role prey prey proximal_promoter_plus_exon1+2, intron1+partial_intron2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 3D bcl6-cdkn1b_human_gene-2 8 58 unspecified role unspecified role bait bait 51 unspecified role unspecified role prey prey proximal_and_distal_promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 3E bcl6-prdm1_human_gene-1 8 21 unspecified role unspecified role bait bait 51 unspecified role unspecified role prey prey proximal_and_distal_promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 3Ei bcl6-prdm1_human_gene-2 9 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 58 unspecified role unspecified role bait bait association association 5A, Supp 5B CHEBI:133537 decreases binding of P41182 to ENSG00000057657 CHEMBL2204995 causes no change in the binding of P41182 to ENSG00000057657 bcl6-cdkn1b_human_gene-3 9 58 unspecified role unspecified role bait bait 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5A, Supp 5B CHEMBL2204995 decreases binding of P41182 to ENSG00000111276 CHEBI:133537 decreases binding of P41182 to ENSG00000111276 bcor-cdkn1b_human_gene-1 4 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role prey prey 29 unspecified role unspecified role bait bait association association 5A-1 bcor-prdm1_human_gene-1 9 21 unspecified role unspecified role bait bait 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5A, 6I, Supp 5B CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000057657 CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000057657 Q9HC52 increases the binding of Q6W2J9 to ENSG00000057657 CBX8 shRNA bcl6-cdkn1b_human_gene-4 9 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role bait bait association association 5Ai, Supp 5B CHEMBL2204995 decreases binding of Q15910 to ENSG00000111276 bcl6-prdm1_human_gene-3 9 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role bait bait association association 5Aii, Supp 5B CHEMBL2204995 decreases binding of Q15910 to ENSG00000057657 bcl6-cdkn1b_human_gene-5 4 29 unspecified role unspecified role bait bait 58 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5A-2 bcor-prdm1_human_gene-2 4 29 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5A-7 bcl6-prdm1_human_gene-4 4 29 unspecified role unspecified role prey prey 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 58 unspecified role unspecified role bait bait association association 5A-8 bcor-cdkn1b_human_gene-2 4 29 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait association association 5A-3 ezh2-bcor-1 4 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role prey prey 29 unspecified role unspecified role bait bait association association 5A-5 ezh2-bcl6-1 4 29 unspecified role unspecified role bait bait 58 unspecified role unspecified role prey prey 51 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5A-6 bcl6-ezh2-1 4 29 unspecified role unspecified role prey prey 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 58 unspecified role unspecified role bait bait association association 5A-4 bcor-prdm1_human_gene-3 9 21 unspecified role unspecified role bait bait 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5Aiii, 6I, Supp fig 5B CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000111276 CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000111276 Q9HC52 increases the binding of Q6W2J9 to ENSG00000111276 CBX8 shRNA ezh2-cdkn1b_human_gene-1 10 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role bait bait association association 5 B/C-1 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of Q15910 to ENSG00000111276 ezh2-cdkn1b_human_gene-2 10 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 49 unspecified role unspecified role bait bait association association 5 B/C-2 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of O75530 to ENSG00000111276 eed-cdkn1b_human_gene-1 10 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 35 unspecified role unspecified role bait bait association association 5 B/C-3 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of Q15022 to ENSG00000111276 suz12-cdkn1b_human_gene-1 10 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait association association 5 B/C-4 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000111276 BCL6 inhibitor FX1:CHEBI:133537 CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000111276 bcor-cdkn1b_human_gene-3 10 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 59 unspecified role unspecified role bait bait association association 5 B/C-5 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of Q99496 to ENSG00000111276 BCL6 inhibitor : FX1 -CHEBI:133537 CHEBI:133537 decreases binding of Q99496 to ENSG00000111276 rnf2-cdkn1b_human_gene-1 10 36 unspecified role unspecified role bait bait 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5 B/C-6 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of Q8NHM5 to ENSG00000111276 BCL6 inhibitor FX1:CHEBI:133537 CHEBI:133537 decreases binding of Q8NHM5 to ENSG00000111276 kdm2b-cdkn1b_human_gene-1 10 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait association association 5B-7 EZH2 inhibitor: GSK343 (CHEMBL2204995) CHEMBL2204995 decreases binding of Q9BSM1 to ENSG00000111276 BCL6 inhibitor : FX1 -CHEBI:133537 CHEBI:133537 decreases binding of Q9BSM1 to ENSG00000111276 bcl6-cdkn1b_human_gene-6 10 58 unspecified role unspecified role bait bait 26 unspecified role unspecified role prey prey promoter_regions binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 5 B/C-8 BCL6 inhibitor : FX1 -CHEBI:133537 CHEBI:133537 decreases the binding of P41182 to ENSG00000111276 pcgf1-bcor-3 7 36 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 37 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 59 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 21 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 17 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 6D pcgf1-bcor-4 7 36 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 59 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Q99496:p.Tyr262Ala mutation mutation certain certain sequence position certain certain certain sequence position certain Y A Wed May 02 19:47:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr262ala' Tue Jun 30 19:51:58 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr262Ala' 21 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 17 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 6D-2 pcgf1-bcor-5 7 36 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 59 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range 21 unspecified role unspecified role prey prey n_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 17 unspecified role unspecified role bait bait region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association 6D-3 An ile375asp mutation in CBX8 disrupted binding of this molecule. 245rwa-1 5 37 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 6E, Supp 6C bcor-cbx8-1 5 37 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey physical association physical association 6E-2 bcor-cbx8-2 3 37 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 6E, Supp 6C cbx8-bcor-1 3 37 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey physical association physical association 6E-2 cbx8-bcor-2 6 21 unspecified role unspecified role prey prey 37 unspecified role unspecified role bait bait physical association physical association 6F-2 bcor-cbx8-3 6 37 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association 6F 346ye5t-1 9 47 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role bait bait association association 6G-1 CHEMBL2204995 -GSK343 CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000124762 Q9HC52 decreases expression at RNA level of ENSG00000124762 CHEMBL2204995 increases expression at RNA level of ENSG00000124762 CHEBI:133537 increases expression at RNA level of ENSG00000124762 CHEBI:133537 and CHEMBL2204995 synergistically increases expression at RNA level of ENSG00000124762 cbx8-cdkn1a_human_gene-1 9 26 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role bait bait association association 6G-2 CHEMBL2204995 -GSK343 CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000111276 cbx8-cdkn1b_human_gene-1 9 51 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role bait bait association association 6G-3 CHEMBL2204995 -GSK343 CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000057657 Q9HC52 decreases expression at RNA level of ENSG00000057657 CHEBI:133537 and CHEMBL2204995 synergistically increases expression at RNA level of ENSG00000057657 CHEBI:133537 increases expression at RNA level of ENSG00000057657 CHEMBL2204995 increases expression at RNA level of ENSG00000057657 cbx8-prdm1_human_gene-1 9 61 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role bait bait association association 6G-4 CHEMBL2204995 -GSK343 CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000137265 Q9HC52 decreases expression at RNA level of ENSG00000137265 CHEBI:133537 increases expression at RNA level of ENSG00000137265 CHEMBL2204995 increases expression at RNA level of ENSG00000137265 cbx8-irf4-1 9 30 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role bait bait association association 6G-5 CHEMBL2204995 -GSK343 CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000116017 cbx8-arid3b-1 9 22 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 37 unspecified role unspecified role bait bait association association 6G-6 CHEMBL2204995 -GSK343 CHEMBL2204995 decreases the binding of Q9HC52 to ENSG00000179361 cbx8-cdkn1a_human_gene-2 9 47 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait association association 6I-1 (Supp 5B) CBX8 shRNA Q9HC52 increases the binding of Q6W2J9 to ENSG00000124762 Supplementary figure 5B appears to show minimal binding between BCOR and CDKN1A cbx8-irf4-2 9 61 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait association association 6I-4, Supp 5B CBX8 shRNA Q9HC52 increases the binding of Q6W2J9 to ENSG00000137265 CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000137265 CHEMBL2204995 decreases binding of Q6W2J9 toENSG00000137265 cbx8-arid3a-1 9 30 unspecified role unspecified role prey prey promoter_region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait association association 6I-5, Supp 5B CBX8 shRNA Q9HC52 increases the binding of Q6W2J9 to ENSG00000116017 CHEBI:133537 decreases binding of Q6W2J9 to ENSG00000116017 CHEMBL2204995 decreases binding of Q6W2J9 to ENSG00000116017 4ey7y-1 1 36 unspecified role unspecified role prey prey 34 unspecified role unspecified role prey prey 60 unspecified role unspecified role prey prey 38 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 40 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 52 unspecified role unspecified role prey prey 45 unspecified role unspecified role prey prey 54 unspecified role unspecified role prey prey 37 unspecified role unspecified role prey prey 48 unspecified role unspecified role prey prey 19 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 33 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 59 unspecified role unspecified role prey prey 53 unspecified role unspecified role prey prey 46 unspecified role unspecified role prey prey 43 unspecified role unspecified role prey prey 44 unspecified role unspecified role prey prey 55 unspecified role unspecified role prey prey 31 unspecified role unspecified role prey prey 15 unspecified role unspecified role prey prey 62 unspecified role unspecified role prey prey 50 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 27 unspecified role unspecified role prey prey 32 unspecified role unspecified role prey prey 65 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 57 unspecified role unspecified role prey prey 64 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait his,cbp,flag_tags tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range c_terminus ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range association association Table S2 pcgf1-amot-1 1 36 unspecified role unspecified role prey prey 21 unspecified role unspecified role prey prey 12 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 56 unspecified role unspecified role prey prey 39 unspecified role unspecified role prey prey 27 unspecified role unspecified role prey prey 37 unspecified role unspecified role prey prey 48 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 33 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 59 unspecified role unspecified role prey prey 46 unspecified role unspecified role prey prey 11 unspecified role unspecified role prey prey 65 unspecified role unspecified role prey prey 41 unspecified role unspecified role prey prey 57 unspecified role unspecified role prey prey 64 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait proteinA,TEV,cbp_tags tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined n_terminus flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range 63 unspecified role unspecified role prey prey 20 unspecified role unspecified role prey prey 18 unspecified role unspecified role prey prey 42 unspecified role unspecified role prey prey association association Table S3 bcl6-bmi1-1 8 58 unspecified role unspecified role bait bait 28 unspecified role unspecified role prey prey proximal_promoter_plus_exons 1-3, introns1-2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Supp 3C bcl6-bmi1-2 8 21 unspecified role unspecified role bait bait 28 unspecified role unspecified role prey prey proximal_promoter_plus_exons 1-3, introns1-2 binding region binding-associated region binding region undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association Supp 3C-2 pcgf1-bcor-6 2 37 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q9HC52:p.Ile375Asp mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength certain certain sequence position certain certain certain sequence position certain I D Wed May 02 20:07:00 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile375asp' Tue Jun 30 19:28:54 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile375Asp' 21 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey association association Supp 6B