I2D I2D PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. Oncogene (0950-9232) 2011 imex curation Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu 26-Sep-2011: Contacted by JYOTI. mgt Only protein-protein interactions Curated by: I2D - Interologous Interaction Database in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu Accepted 2011-JUL-12 by MGT 26-Sep-2011: Contacted by JYOTI. Oncogene (0950-9232) 2011 mgt Only protein-protein interactions imex curation Curated by: I2D - Interologous Interaction Database PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. Oncogene (0950-9232) 2011 imex curation Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu 26-Sep-2011: Contacted by JYOTI. mgt Only protein-protein interactions Curated by: I2D - Interologous Interaction Database human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu Accepted 2011-JUL-12 by MGT 26-Sep-2011: Contacted by JYOTI. Oncogene (0950-9232) 2011 mgt Only protein-protein interactions imex curation Curated by: I2D - Interologous Interaction Database PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. Oncogene (0950-9232) 2011 imex curation Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu 26-Sep-2011: Contacted by JYOTI. mgt Only protein-protein interactions Curated by: I2D - Interologous Interaction Database human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu Accepted 2011-JUL-12 by MGT 26-Sep-2011: Contacted by JYOTI. Oncogene (0950-9232) 2011 mgt Only protein-protein interactions imex curation Curated by: I2D - Interologous Interaction Database PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization. Oncogene (0950-9232) 2011 imex curation Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu 26-Sep-2011: Contacted by JYOTI. mgt Only protein-protein interactions Curated by: I2D - Interologous Interaction Database human-t47d human breast cancer tumour cell line-epithelial cells t47d Epithelial cells derived from human breast tumour anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Zhi HY., Hou SW., Li RS., Basir Z., Xiang Q., Szabo A., Chen G. Cancer - Interactions investigated in the context of cancer VDR-V5 construct is human according to given reference Li et al, 2007, J. Biol. Chem 282: 1544-1551. gchen@mcw.edu Accepted 2011-JUL-12 by MGT 26-Sep-2011: Contacted by JYOTI. Oncogene (0950-9232) 2011 mgt Only protein-protein interactions imex curation Curated by: I2D - Interologous Interaction Database ptn3_human Tyrosine-protein phosphatase non-receptor type 3 Protein-tyrosine phosphatase H1 PTPN3 PTPH1 protein protein human Homo sapiens Human MTSRLRALGGRINNIRTSELPKEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS DIP protein P26045 original sequence version: 155 DIP protein P26045-1 original sequence version: 152 44FBBFA35A5F2AFF vdr_human Vitamin D3 receptor 1,25-dihydroxyvitamin D3 receptor Nuclear receptor subfamily 1 group I member 1 VDR NR1I1 protein protein human Homo sapiens Human MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS DIP protein P11473 original sequence version: 179 DIP protein P11473 original sequence version: 146 F95F300D042C4CB7 vdr-ptpn3 3 6 unspecified role unspecified role bait bait region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 5 unspecified role unspecified role prey prey physical association physical association 6a, S1c vdr-ptpn3-1 4 6 unspecified role unspecified role bait bait region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 5 unspecified role unspecified role prey prey physical association physical association 7a vdr-ptpn3-2 1 5 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. 6 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ligand_binding_domain required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain n_terminal_region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) physical association physical association S2b vdr-ptpn3-3 2 6 unspecified role unspecified role bait bait region v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 5 unspecified role unspecified role prey prey region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association S2d