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        <fullName>European Bioinformatics Institute</fullName>
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        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
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          <fullName>Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1.</fullName>
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            <attribute name="publication title" nameAc="MI:1091">Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1.</attribute>
            <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2006</attribute>
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            <attribute name="imex curation" nameAc="MI:0959"/>
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            <attribute name="author-announcement">24-JAN-2007: Contacted by JYOTI.</attribute>
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              <shortLabel>rat-h4iie</shortLabel>
              <fullName>Rat hepatoma cell line H4IIE</fullName>
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                <fullName>Rat hepatoma cell line H4IIE</fullName>
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          <attribute name="accepted">Accepted 2006-AUG-29 by JYOTI.</attribute>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030520" version="SP_138"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032091" version="SP_138"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_138"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033146" version="SP_138"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034969" version="SP_138"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034970" version="SP_138"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034971" version="SP_138"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3B3G"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3B3J"/>
          <secondaryRef db="rgd" dbAc="MI:0483" id="1305879"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001025212.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001029260.1"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020989"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2OQB"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3B3F"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-400206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-9707564" version="SP_138"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-9018519"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR025799"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029063"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011993"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-3214858"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10116">
          <names>
            <shortLabel>rat</shortLabel>
            <fullName>Rattus norvegicus (Rat)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rat</alias>
          </names>
        </organism>
        <sequence>MAAAAATAVGPGAGSAGVAGPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEVRAGPDAAGIALYSHEDVCVFKCSVSRETECSRVGRQSFIITLGCNSVLIQFATPHDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGVAVAGMPTAYDLSSVIAGGSSVGHNNLIPLANTGIVNHTHSRMGSIMSTGIVQGNRVAGPWAGDLPPGLRTRSSYQWGPGRLRGHAGSSVPMTCPTGSSGAQGGGGSSSAHYAVNNQFTMGGPAISMASPMSIPTNTMHYGS</sequence>
        <attributeList>
          <attribute name="crc64">2C71ED2D8E1BE12F</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-14479-1">
        <names>
          <shortLabel>carm1-creb</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-973418" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-14479-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="6">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Figure 4B</attribute>
          <attribute name="agonist" nameAc="MI:0625">Forskolin</attribute>
          <attribute name="caution" nameAc="MI:0618">There are four variants of Coactivator-associated arginine methyltransferase 1 protein and the specfic variant recognised by the antibody used for coimmunoprecipitaion is not stated in the text.</attribute>
          <attribute name="source-text">Co-immunoprecipitation assay of CREB  and CARM1 endogenous proteins in H4IIE hepatocytes.</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>