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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>UniProt</shortLabel>
        <fullName>UniProt</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0486" refType="identity" refTypeAc="MI:0356"/>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="21225229" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3892963" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-16863" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins.</attribute>
            <attribute name="journal" nameAc="MI:0885">Int. J. Oncol. (1019-6439)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2011</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Platica M., Ionescu A., Ivan E., Holland JF., Mandeli J., Platica O.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
            <attribute name="contact-email" nameAc="MI:0634">ovidiu.platica@va.gov</attribute>
            <attribute name="author-announcement">26-Jun-2011: Contacted by JYOTI.</attribute>
            <attribute name="reviewer">jyoti</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="21225229" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16863" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-du_145</shortLabel>
              <fullName>Homo sapiens DU-145 prostate cancer cell line</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>du_145</shortLabel>
                <fullName>DU-145</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ACC 261" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="cabri" dbAc="MI:0246" id="ICLC HTL99013" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">Human prostate carcinoma established from the tumor tissue removed from the metastatic central nervous system lesion of a 69-year-old man with prostate carcinoma in 1975 confirmed as human with IEF of AST, MDH, NP</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Platica M., Ionescu A., Ivan E., Holland JF., Mandeli J., Platica O.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
          <attribute name="contact-email" nameAc="MI:0634">ovidiu.platica@va.gov</attribute>
          <attribute name="accepted">Accepted 2011-JUN-13 by ORCHARD</attribute>
          <attribute name="author-announcement">26-Jun-2011: Contacted by JYOTI.</attribute>
          <attribute name="journal" nameAc="MI:0885">Int. J. Oncol. (1019-6439)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2011</attribute>
          <attribute name="reviewer">jyoti</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>birc5_human</shortLabel>
          <fullName>Baculoviral IAP repeat-containing protein 5</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Apoptosis inhibitor survivin</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Apoptosis inhibitor 4</alias>
          <alias type="gene name" typeAc="MI:0301">BIRC5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">API4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IAP4</alias>
        </names>
        <xref>
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          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2I3N8" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VGX0" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53F61" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5MGC6" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6FHL2" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
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          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-979338" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A2SUH6" version="SP_148" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-518823" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001012270.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001012271.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001159.2"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000086" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000228" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000278" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000281" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000775" version="SP_232"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_232"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005876" version="SP_232"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007094" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007605" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008017" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015631" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030496" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031021" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031267" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031503" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031536" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032133" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043027" version="SP_232"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045931" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050897" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051087" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051303" version="SP_232"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" version="SP_232"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001370" version="SP_232"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1F3H" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XOX" version="SP_232"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UED" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UEE" version="SP_232"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UII" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UIJ" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UIK" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A0I" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A0J" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4A0N" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6SHO" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIE" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIF" version="SP_232"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIH" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-141444" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2467813" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2500257" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4615885" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5663220" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785807" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6803205" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68877" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8951664" version="SP_232"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648025" version="SP_232"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="O15392"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-34662N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein O15392 original sequence version: 129</attribute>
          <attribute name="remark-internal">DIP protein O15392 original sequence version: 132</attribute>
          <attribute name="remark-internal">DIP protein O15392-1 original sequence version: 141</attribute>
          <attribute name="remark-internal">DIP protein O15392-1 original sequence version: 143</attribute>
          <attribute name="crc64">9E7CADCDF2822286</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>aurka_human</shortLabel>
          <fullName>Aurora kinase A</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">AIRK1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Serine/threonine-protein kinase 15</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Aurora/IPL1-related kinase 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Breast tumor-amplified kinase</alias>
          <alias type="gene name synonym" typeAc="MI:0302">STK6</alias>
          <alias type="gene name synonym" typeAc="MI:0302">AIK</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ARK1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">AURA</alias>
          <alias type="gene name synonym" typeAc="MI:0302">BTAK</alias>
          <alias type="gene name synonym" typeAc="MI:0302">STK15</alias>
          <alias type="gene name" typeAc="MI:0301">AURKA</alias>
          <alias type="gene name synonym" typeAc="MI:0302">AYK1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IAK1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Aurora 2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Serine/threonine-protein kinase 6</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Serine/threonine-protein kinase aurora-A</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O14965" version="SP_88" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O60445" version="SP_88" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O75873" version="SP_88" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BQD6" version="SP_88" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UPG5" version="SP_88" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E1P5F9" version="SP_129" refType="secondary-ac" refTypeAc="MI:0360"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000321591" version="SP_234" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000360407" version="SP_234" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000379250" version="SP_234" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003591.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_940835.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_940836.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_940837.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_940838.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_940839.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001310232.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001310233.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001310234.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016883524.1"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3M11" version="SP_234"/>
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            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein O14965 original sequence version: 181</attribute>
          <attribute name="remark-internal">DIP protein O14965 original sequence version: 146</attribute>
          <attribute name="remark-internal">DIP protein O14965 original sequence version: 124</attribute>
          <attribute name="remark-internal">DIP protein O14965 original sequence version: 160</attribute>
          <attribute name="remark-internal">DIP protein O14965 original sequence version: 138</attribute>
          <attribute name="remark-internal">DIP protein O14965 original sequence version: 98</attribute>
          <attribute name="crc64">125F3594834CD157</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>ince_human</shortLabel>
          <fullName>Inner centromere protein</fullName>
          <alias type="gene name" typeAc="MI:0301">INCENP</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NQS7" version="SP_52" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5Y192" version="SP_52" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8MQD2" version="SP_62" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000378295" version="SP_181" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-307907" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001035784.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_064623.2"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000070" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000281" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000775" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000776" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000793" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000800" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000801" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005721" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005819" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005874" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007059" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010032" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010369" version="SP_181"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000149503" version="SP_181" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016572" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030496" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032133" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043539" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051257" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051310" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071902" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902412" version="SP_181"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990385" version="SP_181"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005635" version="SP_181"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022006" version="SP_181"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039130" version="SP_181"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q9NQS7" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2QFA" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4AF3" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IEH" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5IEK" version="SP_181"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000394818" version="SP_181" refType="transcript"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GR8" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6GR9" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIE" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIF" version="SP_181"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YIH" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-141444" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2467813" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2500257" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4615885" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5663220" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68877" version="SP_181"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648025" version="SP_181"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-31304N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSVLRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSPPLQGARVPSSLAYSLKKH</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q9NQS7 original sequence version: 83</attribute>
          <attribute name="remark-internal">DIP protein Q9NQS7 original sequence version: 86</attribute>
          <attribute name="crc64">644D081DCC9035E8</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>jtb_human</shortLabel>
          <fullName>Protein JTB</fullName>
          <alias type="gene name" typeAc="MI:0301">JTB</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Jumping translocation breakpoint protein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Prostate androgen-regulated protein</alias>
          <alias type="orf name" typeAc="MI:0306">HSPC222</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O76095" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6IB19" version="SP_84" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9P0Q4" version="SP_84" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O95442" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000271843" version="SP_161" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2339818" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006685.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000143543"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000143543" version="SP_161" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000271843" version="SP_161" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000278" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000281" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005815" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005819" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030496" version="SP_161"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045860" version="SP_161"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008657" version="SP_161"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2KJX" version="SP_161"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MLAGAGRPGLPQGRHLCWLLCAFTLKLCQAEAPVQEEKLSASTSNLPCWLVEEFVVAEECSPCSNFRAKTTPECGPTGYVEKITCSSSKRNEFKSCRSALMEQRLFWKFEGAVVCVALIFACLVIIRQRQLDRKALEKVRKQIESI</sequence>
        <attributeList>
          <attribute name="crc64">CA7080543591C319</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6" imexId="IM-16863-1">
        <names>
          <shortLabel>aurka-jtb-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-3892977" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16863-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="8">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">fig 5</attribute>
        </attributeList>
      </interaction>
      <interaction id="9" imexId="IM-16863-2">
        <names>
          <shortLabel>birc5-aurkb-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-3892994" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16863-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="10">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="11">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="12">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">fig 6,</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>