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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
      <bibref>
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        </xref>
      </bibref>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="12743605" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1992082" refType="identity" refTypeAc="MI:0356"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia.</attribute>
            <attribute name="journal" nameAc="MI:0885">Oncogene (0950-9232)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2003</attribute>
            <attribute name="author-list" nameAc="MI:0636">Bowers AJ., Scully S., Boylan JF.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="12743605" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-u2-os</shortLabel>
              <fullName>Human U2-OS osteosarcoma cell line</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>u2-os</shortLabel>
                <fullName>U2-OS osteocaroma cell line</fullName>
              </names>
              <xref>
                <primaryRef db="intact" dbAc="MI:0469" id="IA:0107" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-492418" refType="identity" refTypeAc="MI:0356"/>
              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">Not in CAPRI and no primary literature reference</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti tag coip</shortLabel>
            <fullName>anti tag coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Bowers AJ., Scully S., Boylan JF.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
          <attribute name="accepted"/>
          <attribute name="journal" nameAc="MI:0885">Oncogene (0950-9232)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2003</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="12743605" refType="primary-reference" refTypeAc="MI:0358"/>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia.</attribute>
            <attribute name="journal" nameAc="MI:0885">Oncogene (0950-9232)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2003</attribute>
            <attribute name="author-list" nameAc="MI:0636">Bowers AJ., Scully S., Boylan JF.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
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        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="12743605" refType="primary-reference" refTypeAc="MI:0358"/>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="4932">
            <names>
              <shortLabel>yeasx</shortLabel>
              <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
              <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>2 hybrid</shortLabel>
            <fullName>two hybrid</fullName>
            <alias type="go synonym" typeAc="MI:0303">2H</alias>
            <alias type="go synonym" typeAc="MI:0303">2h</alias>
            <alias type="go synonym" typeAc="MI:0303">Gal4 transcription regeneration</alias>
            <alias type="go synonym" typeAc="MI:0303">two-hybrid</alias>
            <alias type="go synonym" typeAc="MI:0303">yeast two hybrid</alias>
            <alias type="go synonym" typeAc="MI:0303">2-hybrid</alias>
            <alias type="go synonym" typeAc="MI:0303">classical two hybrid</alias>
            <alias type="synonym" typeAc="MI:1041">classical two hybrid</alias>
            <alias type="synonym" typeAc="MI:1041">2H</alias>
            <alias type="synonym" typeAc="MI:1041">two-hybrid</alias>
            <alias type="synonym" typeAc="MI:1041">2-hybrid</alias>
            <alias type="synonym" typeAc="MI:1041">Gal4 transcription regeneration</alias>
            <alias type="synonym" typeAc="MI:1041">2h</alias>
            <alias type="synonym" typeAc="MI:1041">yeast two hybrid</alias>
            <alias type="synonym" typeAc="MI:1041">Y2H</alias>
            <alias type="synonym" typeAc="MI:1041">Y-2H</alias>
            <alias type="synonym" typeAc="MI:1041">2 hybrid</alias>
          </names>
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            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-94" refType="identity" refTypeAc="MI:0356"/>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>nucleotide sequence</shortLabel>
            <fullName>nucleotide sequence identification</fullName>
            <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
            <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
            <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Bowers AJ., Scully S., Boylan JF.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
          <attribute name="accepted"/>
          <attribute name="journal" nameAc="MI:0885">Oncogene (0950-9232)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2003</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>atf5_human</shortLabel>
          <fullName>Cyclic AMP-dependent transcription factor ATF-5</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Activating transcription factor 5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Transcription factor ATFx</alias>
          <alias type="gene name" typeAc="MI:0301">ATF5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ATFX</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9Y2D1" version="SP_67" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000470633" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029855" version="SP_178"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648895" version="SP_178"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003700" version="SP_178"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000169136" version="SP_178" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000423777" version="SP_178" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000595125" version="SP_178" refType="transcript"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011524931.1"/>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC</sequence>
        <attributeList>
          <attribute name="crc64">DDB2F907CA0215A0</attribute>
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      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>atf4_human</shortLabel>
          <fullName>Cyclic AMP-dependent transcription factor ATF-4</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Activating transcription factor 4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CREB2</alias>
          <alias type="gene name" typeAc="MI:0301">ATF4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">TXREB</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cyclic AMP-responsive element-binding protein 2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Tax-responsive enhancer element-binding protein 67</alias>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990589" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990590" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990617" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_226"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004827" version="SP_226"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029811" version="SP_226"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P18848" version="SP_226"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1CI6" version="SP_226"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-380994" version="SP_226"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-381042" version="SP_226"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-381183" version="SP_226"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9633012" version="SP_226"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648895" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043005" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043522" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043525" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045667" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034198" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034399" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034599" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034644" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034976" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035162" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0036003" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0036091" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0036499" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042149" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042789" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045943" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048167" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061395" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" version="SP_226"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000337304" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000396680" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000404241" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000674568" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000674835" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000674920" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000676346" version="SP_226" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000679776" version="SP_226" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000977" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_226"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_226"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016884296.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-354N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP</sequence>
        <attributeList>
          <attribute name="crc64">3BBB7379DC3B0D07</attribute>
          <attribute name="remark-internal">DIP protein P18848 original sequence version: 181</attribute>
          <attribute name="remark-internal">DIP protein P18848 original sequence version: 117</attribute>
          <attribute name="comment" nameAc="MI:0612">No Uniprot Update and Caution  removed " The protein could not be merged with EBI-12907955 because of some conflicts with the protein sequence (features which cannot be shifted)." -EBI-12907955 no longer exists.</attribute>
          <attribute name="crc64">3BBB7379DC3B0D07</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>trib3_human</shortLabel>
          <fullName>Tribbles homolog 3</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Neuronal cell death-inducible putative kinase</alias>
          <alias type="gene name synonym" typeAc="MI:0302">p65-interacting inhibitor of NF-kappa-B</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SINK</alias>
          <alias type="gene name" typeAc="MI:0301">TRIB3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">C20orf97</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NIPK</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SKIP3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">TRB3</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q96RU7" version="SP_59" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53GU4" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53ZW7" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6I9Y9" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8TAI6" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H5M8" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NUD2" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000217233" version="SP_186" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-492476" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_066981.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288117.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288119.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288122.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288125.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001288130.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000101255" version="SP_186" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000217233" version="SP_186" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004860" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006469" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010506" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010827" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031434" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003714" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032092" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032436" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032869" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034976" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043405" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045599" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045717" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051443" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0055106" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070059" version="SP_186"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_186"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_186"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024104" version="SP_186"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024106" version="SP_186"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q96RU7" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1257604" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-165158" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1989781" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-199418" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-389357" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5218920" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9633012" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9648895" version="SP_186"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG</sequence>
        <attributeList>
          <attribute name="crc64">CE15FD89A81E8D63</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6">
        <names>
          <shortLabel>trib3-atf4-3</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-492506" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="8">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="9">
        <names>
          <shortLabel>trib3-atf5-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-492520" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="10">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="11">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="12">
        <names>
          <shortLabel>trib3-atf4-4</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-492526" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="13">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="14">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-492531" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>myc tag</shortLabel>
                    <fullName>myc tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">EUKLISEED epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">EUKLISEED epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0522" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456561" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="15">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="16">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-492529" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>ha tag</shortLabel>
                    <fullName>ha tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">YPYDVPDYA epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">YPYDVPDYA epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>