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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
      <bibref>
        <xref>
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        </xref>
      </bibref>
      <xref>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>The apoptotic signaling pathway activated by Toll-like receptor-2.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="10880445" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1990831" refType="identity" refTypeAc="MI:0356"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">The apoptotic signaling pathway activated by Toll-like receptor-2.</attribute>
            <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2000</attribute>
            <attribute name="author-list" nameAc="MI:0636">Aliprantis AO., Yang RB., Weiss DS., Godowski P., Zychlinsky A.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="10880445" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-293t</shortLabel>
              <fullName>Homo sapiens 293 cells transformed with SV40 large T antigen</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>293t</shortLabel>
                <fullName>293 cells expressing SV40 large T antigen.</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ICLC HTL04001" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="cabri" dbAc="MI:0246" id="ACC 635" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="pubmed" dbAc="MI:0446" id="3031469" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
              <attributeList>
                <attribute name="comment" nameAc="MI:0612">The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB.</attribute>
              </attributeList>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>coip</shortLabel>
            <fullName>coimmunoprecipitation</fullName>
            <alias type="go synonym" typeAc="MI:0303">co-immunoprecipitation</alias>
            <alias type="go synonym" typeAc="MI:0303">CoIp</alias>
            <alias type="go synonym" typeAc="MI:0303">immunoprecipitation</alias>
            <alias type="go synonym" typeAc="MI:0303">Co-IP</alias>
            <alias type="synonym" typeAc="MI:1041">co-immunoprecipitation</alias>
            <alias type="synonym" typeAc="MI:1041">CoIp</alias>
            <alias type="synonym" typeAc="MI:1041">immunoprecipitation</alias>
            <alias type="synonym" typeAc="MI:1041">Co-IP</alias>
            <alias type="synonym" typeAc="MI:1041">coip</alias>
          </names>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Aliprantis AO., Yang RB., Weiss DS., Godowski P., Zychlinsky A.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Apoptosis - Interactions involving proteins with a function related to apoptosis</attribute>
          <attribute name="accepted"/>
          <attribute name="journal" nameAc="MI:0885">EMBO J. (0261-4189)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2000</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>myd88_human</shortLabel>
          <fullName>Myeloid differentiation primary response protein MyD88</fullName>
          <alias type="gene name" typeAc="MI:0301">MYD88</alias>
        </names>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP</sequence>
        <attributeList>
          <attribute name="crc64">CEAE3F6B99524333</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>fadd_human</shortLabel>
          <fullName>FAS-associated death domain protein</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">FAS-associating death domain-containing protein</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Mediator of receptor induced toxicity</alias>
          <alias type="gene name" typeAc="MI:0301">FADD</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MORT1</alias>
          <alias type="orf name" typeAc="MI:0306">GIG3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Growth-inhibiting gene 3 protein</alias>
        </names>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003815.1"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031264" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031265" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032813" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033077" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033612" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035877" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0036462" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042104" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043005" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043029" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043278" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044297" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045651" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045862" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048148" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048535" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048536" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048538" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060340" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060546" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070236" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071550" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0089720" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097049" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097191" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097192" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097202" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097342" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097527" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000454" version="SP_214"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001238" version="SP_214"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000488" version="SP_214"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001875" version="SP_214"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011029" version="SP_214"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016729" version="SP_214"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q13158" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A1W" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A1Z" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1E3Y" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1E41" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2GF5" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EZQ" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3OQ9" version="SP_214"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ACI" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-140534" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2562578" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3371378" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5213460" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5218900" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5357786" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5357905" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5675482" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69416" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-75157" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-75158" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013957" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-933543" version="SP_214"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9693928" version="SP_214"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGAMSPMSWNSDASTSEAS</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q13158 original sequence version: 155</attribute>
          <attribute name="remark-internal">DIP protein Q13158 original sequence version: 130</attribute>
          <attribute name="remark-internal">DIP protein Q13158 original sequence version: 110</attribute>
          <attribute name="remark-internal">DIP protein Q13158 original sequence version: 118</attribute>
          <attribute name="remark-internal">DIP protein Q13158 original sequence version: 141</attribute>
          <attribute name="remark-internal">DIP protein Q13158 original sequence version: 166</attribute>
          <attribute name="crc64">0E65E2F852E83507</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>fadd-myd88</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-518940" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="6">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="7">
                <names>
                  <shortLabel>au1 tagged region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-518945" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>tag</shortLabel>
                    <fullName>tag</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="8">
        <names>
          <shortLabel>fadd-myd88-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-518976" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="9">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="10">
                <names>
                  <shortLabel>region</shortLabel>
                  <fullName>region containing death domain</fullName>
                </names>
                <xref>
                  <primaryRef db="interpro" dbAc="MI:0449" id="IPR000488" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-518983" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="80"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="208"/>
                  </featureRange>
                </featureRangeList>
              </feature>
              <feature id="11">
                <names>
                  <shortLabel>region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-518985" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>ha tag</shortLabel>
                    <fullName>ha tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">YPYDVPDYA epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">YPYDVPDYA epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="12">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="13">
                <names>
                  <shortLabel>au1 tagged region</shortLabel>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-518979" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>tag</shortLabel>
                    <fullName>tag</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
              <feature id="14">
                <names>
                  <shortLabel>region</shortLabel>
                  <fullName>region containing death domain</fullName>
                </names>
                <xref>
                  <primaryRef db="interpro" dbAc="MI:0449" id="IPR000488" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-518981" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="1"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="151"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>