DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ motz-2013-6 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Motz C., Schuhmann KM., Kirchhofer A., Moldt M., Witte G., Conzelmann KK., Hopfner KP. DIP original experiment: DIP-266842X Science (New York, N.Y.) 2013 IMEx Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling. Motz C., Schuhmann KM., Kirchhofer A., Moldt M., Witte G., Conzelmann KK., Hopfner KP. Only protein-protein interactions imex curation h0z993_taegu RNA helicase IFIH1 protein protein taegu Taeniopygia guttata Zebra finch Poephila guttata MAEGTRDERFLYMISCFRPRLKQIIQAQPVLDQLPSLSAEDKDRVRAAALQRGAAAGAEELLRAVERGPRGCGWIREFLQALERGGCSLAACYANPSLSQLPSPAEEAEHDLCVHLVQLLHGTLVDRMRAVQVAEKCLQMGIFQDEDVDRIQTVTDNRGNRDGARELLSRIVQKKDWFSSFLIALRETQHEDLADDLSGNTGESKQNGMEQTTNEETEVTSQPGNVIEENLKQEENVDDSFSSESSLLETSIEKNSVVSESDVSIGDGGVSNSNENLEQSSTTSDSDEDEVERRASPEPDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKKRASEPGKVIVLVNKVPLVEQHLKTEFSPFLKRWYQVIGLSGDSQLKISFPEVVRRNDVIISTAQILENSLLNASKEDEESVHLSDFSLIIIDECHHTQKEGVYNNIMRRYLKEKMKNRKLAKENKPLIPQPQILGLTASPGVGGATSYSKAEEHILKICANLDACRIMTVEEHASQLKNQVKEPSKKTVIADDKKRDPFKEKITEIMTEIQNYCQLHPKTEFGTQTYEQWVIREEKRAAKAEKRRERVCAEHLKKYNDALQINDTIRMVDAYNLLNNFYKEEKSKKTVRSDDDDDDKPAVSKQDETDEFLIGLFHAKKKQLKELTRKPENENEKLMKLRNTLMEEFTKTEEPRGIVFTKTRLSAFALFQWIKDNPKFEEVGIKAHYLIGSGHKSEMKPMTQNEQREVIDKFRCGNVNLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVVSSDSGAVERESVNIYREKMMYKAIQRVQKMPQEEYLNKIHNFQLQSIVEKQMKVMRDQRKTYKKNPSLIKFLCKNCSKSICSGEDIQVIEDMHHVSVKKDFQSLYHIRENKALQDKHADNQTNGEIICKDCGQAWGNMMVHRGLDLPCLKIRNFVVVFADKKTTNDIFKKWGDLPIRFPSFDYASHCPSSDED v_piv5 Non-structural protein V P/V protein protein sv5 Simian virus 5 (strain W3) PIV5 Simian virus 5 MDPTDLSFSPDEINKLIETGLNTVEYFTSQQVTGTSSLGKNTIPPGVTGLLTNAAEAKIQESTNHQKGSVGGGAKPKKPRPKIAIVPADDKTVPGKPIPNPLLGLDSTPSTQTVLDLSGKTLPSGSYKGVKLAKFGKENLMTRFIEEPRENPIATSSPIDFKRGRDTGGFHRREYSIGWVGDEVKVTEWCNPSCSPITAAARRFECTCHQCPVTCSECERDT ifih1-p/v-3 3249621 N/A 3249635 unspecified role unspecified role unspecified role unspecified role Region 363-935 Region 363-935 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3249630 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false