DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ idnurm-2005-1 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Idnurm A., Heitman J. DIP original experiment: DIP-110964X PLoS biology 2005 IMEx Light controls growth and development via a conserved pathway in the fungal kingdom. Idnurm A., Heitman J. Only protein-protein interactions imex curation idnurm-2005-2 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Idnurm A., Heitman J. DIP original experiment: DIP-110965X PLoS biology 2005 IMEx Light controls growth and development via a conserved pathway in the fungal kingdom. Idnurm A., Heitman J. Only protein-protein interactions imex curation q5egq2_cryne BWC1 protein protein cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans SVDYTYSIPPEKPLQLDGKGAAIAGLSTAVLDIMGSRTKALAAGTEEGARMEWFKMILDNTDDFIHALSLKGFFQYASSSIRRSLGYEPEDLLNKNISEFAHPSDIVPVIRALKDSTQTIGEEQQPKPVHFTFRIRTKNFGYVWVESMGRLVVEAGKGRKAVILSGRVRNMPTLSWGKVAEHGGLAKTEFWAKISFQGLLLNLTFGVDKVLGYQAEEILGRNLFSLLPGGQNTPPSGEHLINNYASAPDIAPVAKAIYQTIHDSTHRGALSIRQKMVHRSGQPVDVILVFYAPGQAKDKQSPISYSNNDESASVNFIGTPNGASTYPVKITDIFVQVKLLSSSPSHQRSVQPPSIASLTQARPLVHLPNDNIFEELETGRDSSWQYELHQMKMTNRRLRDSIAALKEKKAGKAKKRKYNIVDESPENQSEIIDTSLSSQIGGIGF q5egq1_cryne BWC2 protein protein cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans MSLLAESLAGAKYMVATNDDRESSTNGAAEFLRRKRWPEILLKELVGSAVFCLKPTLILGSRQYQNGEAWSWKIIYSSPSVYEMLGQRPADLEGRDFFDLVLVDDRPQLQSFFNSLLAPPLLNVEPTLLSSEGPDTLGGSRTTYIRMLSAAPGPSRSDSSSRSSSGQRSLPQSNYGTPVGRILGPVVWEIRAHATGIGEDLGEAAGNGETLRMAADGTVVSAIREGDGKHKAIWLMARQVGEGMNEDQKSLEAFLEVKLENERLLAELQELEEEVGMTVEDSINNNQSASTPSSHSSTDTPPGGDKNKNKAGRPPKTNTQVSASGHKRQKSGTGGPAGASEGETMHVCVTCGRTDSPEWRKGPLGPKTLCNACGLRWAKRNSTHIPKKDKQS bwc1-bwc2-1 3137672 N/A 3137674 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3137675 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction false false false bwc2-bwc1-1 3137673 N/A 3137674 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3137675 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast direct interaction direct interaction false false false MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint hsueh-2009-1 A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. yeast Saccharomyces cerevisiae Baker's yeast ub reconstruction ubiquitin reconstruction ub reconstruction predetermined predetermined participant predetermined Hsueh YP., Xue C., Heitman J. EMBO J. (0261-4189) 2009 Only protein-protein interactions imex curation q6uea7_crynv protein protein crynv Cryptococcus neoformans var. grubii MGGCMSSPATGDPVAEARSKEIDRALKEDEKRMAKEVKLLLLGAGASGKSTILKQMRLIHDRPFESDEVEDYRKLTFSNIVGGMRAIIDVMDELGLAVQPENRRYISLVDAEPPINTNDSYPIKYLTALKRLWEDPSVQECYKRGNEFALAENMPYFYADLDRLFAKGFKPSSDDILRVRSKTTGITETRFPIRDVVFRLFDVGGQRSERRKWASCFENVTAILFLVALSDYNSCLIEDRESNGMQEALMLFDSICNSQWFTKSSIILFLNKADLLQVKIQDPSQQLHENFPEFEGKPYSFQDAVDFFKIKFRSLNRMPQKEIYCHVTTAVDRQNVKVVMTACQDTILKNALRDMAIL mint ppib_crynj Peptidyl-prolyl cis-trans isomerase B CPR2 Rotamase B CNG01060 protein protein crynj Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) MNTSHPIPTTMASKSFLSLLVALFVAICFVLSPGVDAAKGPVITNKVYFDIEHGGKPLGRIVMGLYGKTVPKTAENFRALATGKNSDGEDLGYGYEGSSFHRIIKNFMIQGGDFTKGDGTGGKSIYGSKFPDENFKLKHTGPGVLSMANAGRDTNGSQFFICTVKTAWLDNRHVVFGHVLEGMDVVYAMENVKTSRGDKPVEPITIAASGELPIEHEVDEQGNQVPFRIEL mint q5kls3_crynj CNB04250 protein protein crynj Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) MAFAHPEYLVPSVIALVLALYPLPWHLRTGNIATLSMIFWMTLLNIVHIVNCIVWVDNSAPRAKWWGDISALIIVAYNYALPTAHLVLAKQLESFTSLRPHSPLYDSSSRKRHRIFDISVTIGAPVIGYLVHLSNMDRRFYIVERLGPQAATYWNAWGVIWMAIVPILIAVTVVVYTIMALVNIYLRRQQMLSLIASDASVNRDQFYRLMFLTVSEVGTCGLRAIFNLMSFQNGPQPMGHRGAPFHNLSKIESIEWSSTTTSGRLTLHLSFFTVVACSYVFFMCFATSTETKRFYSNIVRKIFPCIPESRTSRIHKLGSVDTGLSRSNATGTYSSATTGPISPTTPKDMDISLEEMLHAPALGKNSHWAINRGLDRVEITPSVTTQESKYDEETADALYLPSMMNEEKTSSSIV q5khp2_crynj CND05800 protein protein crynj Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) MHDLSLVIFSGIGILLVLLPLPLHWRARNAGTLLLITWLFIANLIFFVDGIVWWNSYDLPSSPIWCDIASKLFIGVPVGISATSLCITRRLVMIASSTAVTITQRQKHIALAVDLLLGIGMPVLVMALHYIVQAHRFDIIEGYGCQPVTWPGVPALFAVTWWSPLLTIIAAGYGIIALRFFLHRRLQFHTVLRSSRSNLDSRHYLRLMALASVDIILGLPATLFTLIVNIQQRQSYPSWDWVHLDWSRIELYPASSILSGAQETIAIVLPRWLAPLLSIIFFLFFGVSIDAMGEYARWYRTIRAKAPFLPFHREDILPIAAPKLGSTIAKPSGADWKDSTIANDDTMEGSYFNDLDRFDSTPGVIRGGIMIAVSVERAVV mint q69fa9_cryne protein protein cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans MSSTTNSHLMKTTRWGRPFVKDTHDLFCTLVASLNFDTHRNFFKTYPNSFTTDDACLNLASLKFSQSTRTADPKDPTRIVTTTTTTTFSMSREMAKGICQHFMDCHLVENATDIMAGFFKDRGIYMLTPKGLHILERFVSKNGITTDHLLKLFATQPITMKLLHLERRSGDDEVIITRNVIEVLFRRFVGRIPNLTKLNEDEILAHYYSRFYTKTPSLPAGETLDRSEGIIVRKPGGGEKTTSSDDYIFSARAAVNWMLDFTSATGIDEAAEILAHFVRYGLITLVSDKGKIKEENLIVSARGGGAGGGAGAIMQEAEFRVTERAIYKITKEGIAVAKWNETTTNHAAGASKANLSVETTPGNKARPSHEASPSVSVQRRTSLSDRFRGDFDISGVPGGDNHIKDSHTARLKQILEEPALRSLFREFLRSNFCEENLSFWLDVQDFKRRFQTTSSAVAAPGSKQAKVSGHAAMEKHQQDLVAMAFVIYNTYLAPASPCELNIDHNLRAELVGYMNQITSDKEAGVKGHIEPGVGDTLHASQLQTMVKLYERIQVYIFRLMATDSVPKFCKTELFLTLMEQFSEYTKDEFAVTDLETKAAALTVDSRKTTAHVDGRQPSPTRSYLTISQAANEKQAAKQKN mint gpa2_yeast Guanine nucleotide-binding protein alpha-2 subunit YER020W GPA2 SSP101 GP2-alpha protein protein yeast Saccharomyces cerevisiae Baker's yeast MGLCASSEKNGSTPDTQTASAGSDNVGKAKVPPKQEPQKTVRTVNTANQQEKQQQRQQQPSPHNVKDRKEQNGSINNAISPTATANTSGSQQINIDSALRDRSSNVAAQPSLSDASSGSNDKELKVLLLGAGESGKSTVLQQLKILHQNGFSEQEIKEYIPLIYQNLLEIGRNLIQARTRFNVNLEPECELTQQDLSRTMSYEMPNNYTGQFPEDIAGVISTLWALPSTQDLVNGPNASKFYLMDSTPYFMENFTRITSPNYRPTQQDILRSRQMTSGIFDTVIDMGSDIKMHIYDVGGQRSERKKWIHCFDNVTLVIFCVSLSEYDQTLMEDKNQNRFQESLVLFDNIVNSRWFARTSVVLFLNKIDLFAEKLSKVPMENYFPDYTGGSDINKAAKYILWRFVQLNRANLSIYPHVTQATDTSNIRLVFAAIKETILENTLKDSGVLQ 881B91792AE91748 q8j0x5_cryne protein protein cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans MLHPDYPFWNLTALVLVLLPAPWHWRARNIATVSLVVWLTFANLCGFINTIIWAGNYADKSPVWCDISSRVPLLVGYAIPLCSLSQMRRLESVASTRRSLMSSGMRKRRVWEEIIICLLLPVIFTVLQYVVQGHRYDIIEGVGCSNPTFMSVPGLMIRFIVPMVVAVASLIFAALAVRWFLIRRLQFRTILASSDAKLSIGRYFRLIALAVTDSTVVLVVIVYAAANALSDSSLPMRPYRNWAYVHEDFSQVSQYPEELFASSWPAVVMNVYAPILYSILFFTFFGFGEEAVSEYLAIGDKVMQLLEIMGFKGKRSGPVFNDLRIDLGCKIVPAFNGNDLESTPLGNLRDDTSEKGFQDLESRAVKATPLNNMGIAVTVERSVVA mint cpr2-q6uea7 853916 q6uea7_crynv gpa3 853917 predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ppib_cryne CPR2 853918 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Q5KLS3:p.Leu222Pro leu222pro mutation increasing mutation increasing interaction mutation increasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false f5b mint cpr2-q69fa9 853916 ppib_cryne CPR2 853919 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false q69fa9_cryne crg1 853920 predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false f5b mint cpr2-cpr2 853916 ppib_cryne CPR2 853919 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ppib_cryne CPR2 853919 predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false f5b mint cpr2-q5khp2 853916 ppib_cryne CPR2 853919 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false q5khp2_cryne ste3 alpha 853921 predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false f5b mint cpr2-q8j0x5 853916 ppib_cryne CPR2 853919 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false q8j0x5_cryne ste3 alpha 853922 predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false f5b mint cpr2-gpa2 853916 gpa2_yeast gpa2 853923 predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ppib_cryne CPR2 853918 predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell fusion proteins fusion protein fusion protein undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false undefined mutation mutation increasing interaction mutation increasing mutation increasing interaction mutation increasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false f5b mint The Saccharomyces cerevisiae Uniprot ID of GPa2 has been used instead of Cryptococcus neoformans one.