DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ chen-2014-14 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Chen L., Dürr KL., Gouaux E. DIP original experiment: DIP-266406X Science (New York, N.Y.) 2014 IMEx X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Chen L., Dürr KL., Gouaux E. Only protein-protein interactions imex curation chen-2014-15 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column weight silver stain molecular weight estimation by silver staining weight silver stain Chen L., Dürr KL., Gouaux E. DIP original experiment: DIP-266409X Science (New York, N.Y.) 2014 IMEx X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Chen L., Dürr KL., Gouaux E. Only protein-protein interactions imex curation chen-2014-16 ecolx Escherichia coli comigration in sds comigration in sds page comigration in sds weight by staining molecular weight estimation by staining weight by staining Chen L., Dürr KL., Gouaux E. DIP original experiment: DIP-266407X Science (New York, N.Y.) 2014 IMEx X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Chen L., Dürr KL., Gouaux E. Only protein-protein interactions imex curation chen-2014-17 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Chen L., Dürr KL., Gouaux E. DIP original experiment: DIP-266410X Science (New York, N.Y.) 2014 IMEx X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Chen L., Dürr KL., Gouaux E. Only protein-protein interactions imex curation chen-2014-18 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Chen L., Dürr KL., Gouaux E. DIP original experiment: DIP-266408X Science (New York, N.Y.) 2014 IMEx X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Chen L., Dürr KL., Gouaux E. Only protein-protein interactions imex curation conii_const Con-ikot-ikot protein protein const Conus striatus Striated cone MAMNMSMTLCMFVMVVVAATVIDSTQLQEPDLSRMRRSGPADCCRMKECCTDRVNECLQRYSGREDKFVSFCYQEATVTCGSFNEIVGCCYGYQMCMIRVVKPNSLSGAHEACKTVSCGNPCA p19491-2 Glutamate receptor 2 Gria2 Glur2 AMPA-selective glutamate receptor 2 GluR-B GluR-K2 Glutamate receptor ionotropic, AMPA 2 protein protein rat Rattus norvegicus (Rat) Rat MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNPQNINPSSSQNSQNFATYKEGYNVYGIESVKI conii_const-1 3268598 N/A 3268603 unspecified role unspecified role unspecified role unspecified role Region 38-123 Region 38-123 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false conii_const-gria2-1 3268599 N/A 3268604 unspecified role unspecified role unspecified role unspecified role Region 25-850 Region 25-850 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3268603 unspecified role unspecified role unspecified role unspecified role Region 38-123 Region 38-123 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false conii_const-2 3268600 N/A 3268603 unspecified role unspecified role unspecified role unspecified role Region 38-123 Region 38-123 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false conii_const-gria2-2 3268601 N/A 3268604 unspecified role unspecified role unspecified role unspecified role Region 25-850 Region 25-850 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3268603 unspecified role unspecified role unspecified role unspecified role Region 38-123 Region 38-123 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false conii_const-3 3268602 N/A 3268603 unspecified role unspecified role unspecified role unspecified role Region 38-123 Region 38-123 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false