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    <entry>
        <source releaseDate="2013-09-02+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
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                </xref>
            </bibref>
            <xref>
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                <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579228" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="666237">
                <names>
                    <shortLabel>huston-2007-1</shortLabel>
                    <fullName>The temperature activated HtrA protease from pathogen Chlamydia trachomatis acts as both a chaperone and protease at 37 degrees C.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="17604025" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-5010412" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1016/j.febslet.2007.06.039" refType="secondary-ac" refTypeAc="MI:0360"/>
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                    <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5220085" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>enzymatic study</shortLabel>
                        <fullName>enzymatic study</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0415" refType="identity" refTypeAc="MI:0356"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608493" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Huston WM., Swedberg JE., Harris JM., Walsh TP., Mathews SA., Timms P.</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2007</attribute>
                    <attribute name="imex-exported">2009-01-08</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"></attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="666238">
                <names>
                    <shortLabel>a0a0h2x3d0_chlta</shortLabel>
                    <fullName>Periplasmic serine endoprotease DegP-like</fullName>
                    <alias typeAc="MI:0301" type="gene name">htrA</alias>
                    <alias typeAc="MI:0305" type="locus name">CTA_0897</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="A0A0H2X3D0" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001940"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041489"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_011324883.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036034"/>
                    <secondaryRef db="ensemblbacteria" id="CTA_0897" version="TrEMBL_27" refType="gene"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="A0A0H2X3D0"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004252" secondary="serine-type endopeptidase activity" version="TrEMBL_27"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7483161" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042597" secondary="periplasmic space" version="TrEMBL_27"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009003"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001478"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011782"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q3KKL6" version="TrEMBL_17" refType="uniprot-removed-ac"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-5010371" refType="intact-secondary"/>
                    <secondaryRef db="ensemblbacteria" id="AAX51106" version="TrEMBL_27" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblbacteria" id="AAX51106" version="TrEMBL_27" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="315277">
                    <names>
                        <shortLabel>chlta</shortLabel>
                        <fullName>Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B)</fullName>
                    </names>
                </organism>
                <sequence>MMKRLLCVLLSTSVFSSPMLGYSASKKDSKADICLAVSSGDQEVSQEDLLKEVSRGFSRVAAKATPGVVYIENFPKTGNQAIASLGNKRGFQENPFDYFNDEFFNRFFGLPSHREQRRPQQRDAVRGTGFIVSEDGYVVTNHHVVEDAGKIHVTLYDGQKYTAKIVGLDPKTDLAVIKIQAEKLPFLTFGNSDQLQIGDWAIAIGNPFGLQATVTVGVISAKGRNQLHIVDFEDFIQTDAAINPGNSGGPLLNINGQVIGVNTAIVSGSGGYIGIGFAIPSLMAKRVIDQLISDGQVTRGFLGVTLQPIDSELATCYKLEKVYGALVTDVVKGSPAEKAGLRQEDVIVAYNGKEVESLSALRNAISLMMPGTRVVLKIVREGKTIEIPVTVTQIPTEDGVSALQKMGVRVQNITPEICKKLGLAADTRGILVVAVEAGSPAASAGVAPGQLILAVNRQRVASVEELNQVLKNSKGENVLLMVSQGDVVRFIVLKSDE</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="666239">
                <names>
                    <shortLabel>casb_human</shortLabel>
                    <fullName>Beta-casein</fullName>
                    <alias typeAc="MI:0301" type="gene name">CSN2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CASB</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P05814" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031305" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006816" secondary="calcium ion transport" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000117" secondary="negative regulation of cysteine-type endopeptidase activity" version="SP_178"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VAZ9" version="SP_80" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000341030" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001588" version="SP_178"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000635174" version="SP_178" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000489488" version="SP_178" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1642112" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UCM5" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1251985" version="SP_178"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000135222" version="SP_178" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016345" version="SP_178"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001289699.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_178"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016863249.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000353151" version="SP_178" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004869" secondary="cysteine-type endopeptidase inhibitor activity" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004857" secondary="enzyme inhibitor activity" version="SP_178"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_178"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P05814" version="SP_178"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000283030" version="SP_178" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007595" secondary="lactation" version="SP_178"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001882.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQPQPLIYPFVEPIPYGFLPQNILPLAQPAVVLPVPQPEIMEVPKAKDTVYTKGRVMPVLKSPTIPFFDPQIPKLTDLENLHLPLPLLQPLMQQVPQPIPQTLALPPQPLWSVPQPKVLPIPQQVVPYPQRAVPVQALLLNQELLLNPTHQIYPVTQPLAPVHNPISV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-10998-1" id="666240">
                <names>
                    <shortLabel>csn2-htra-4</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-5010409" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7483155" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-10998-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>666237</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="666241">
                        <names>
                            <shortLabel>q3kkl6_chlta</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">HtrA</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-5010410" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7483175" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>666238</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme</shortLabel>
                                <fullName>enzyme</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="666242">
                        <names>
                            <shortLabel>casb_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">beta casein</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-5010411" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7483178" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>666239</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme target</shortLabel>
                                <fullName>enzyme target</fullName>
                                <alias typeAc="MI:0303" type="go synonym">substrate</alias>
                                <alias typeAc="MI:1041" type="synonym">substrate</alias>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>cleavage</shortLabel>
                        <fullName>cleavage reaction</fullName>
                        <alias typeAc="MI:1041" type="synonym">cleavage</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F1</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
