DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ bao-2012-1 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Bao X., Nickels BE., Fan H. DIP original experiment: DIP-251803X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Chlamydia trachomatis protein GrgA activates transcription by contacting the nonconserved region of σ66. Bao X., Nickels BE., Fan H. Only protein-protein interactions imex curation bao-2012-2 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Bao X., Nickels BE., Fan H. DIP original experiment: DIP-251805X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Chlamydia trachomatis protein GrgA activates transcription by contacting the nonconserved region of σ66. Bao X., Nickels BE., Fan H. Only protein-protein interactions imex curation bao-2012-3 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Bao X., Nickels BE., Fan H. DIP original experiment: DIP-251804X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Chlamydia trachomatis protein GrgA activates transcription by contacting the nonconserved region of σ66. Bao X., Nickels BE., Fan H. Only protein-protein interactions imex curation bao-2012-4 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Bao X., Nickels BE., Fan H. DIP original experiment: DIP-251806X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Chlamydia trachomatis protein GrgA activates transcription by contacting the nonconserved region of σ66. Bao X., Nickels BE., Fan H. Only protein-protein interactions imex curation jewett-2006-1 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. DIP original experiment: DIP-263963X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Chlamydial TARP is a bacterial nucleator of actin. Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. Only protein-protein interactions imex curation jewett-2006-3 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. DIP original experiment: DIP-263966X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Chlamydial TARP is a bacterial nucleator of actin. Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. Only protein-protein interactions imex curation jewett-2006-4 in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. DIP original experiment: DIP-263964X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Chlamydial TARP is a bacterial nucleator of actin. Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. Only protein-protein interactions imex curation jewett-2006-5 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. DIP original experiment: DIP-263962X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Chlamydial TARP is a bacterial nucleator of actin. Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. Only protein-protein interactions imex curation jewett-2006-6 in vitro In vitro tem transmission electron microscopy tem predetermined predetermined participant predetermined Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. DIP original experiment: DIP-263965X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Chlamydial TARP is a bacterial nucleator of actin. Jewett TJ., Fischer ER., Mead DJ., Hackstadt T. Only protein-protein interactions imex curation siga_chltr RNA polymerase sigma factor SigA sigA rpoD CT_615 Sigma-66 Sigma-70 Sigma-A protein protein chltr chltr MRMDTLDSQAAEAAQEEEIQRKLEELVTLAKDQGFITYEEINEILPPSFDTPEQIDQVLIFLAGMDVQVLNQADVERQKERKKEAKELEGLAKRSEGTPDDPVRMYLKEMGTVPLLTREEEVEISKRIEKAQVQIERIILRFRYSTKEAVSIAQYLINGKERFDKIVSEKEVEDKTHFLNLLPKLISLLKEEDAYLEERLLALKDPALSKPDQARLNDELEKCRIRTQAYLRCFHCRHNVTEDFGEVVFKAYDSFLQLEQQINDLKARAERNKFAAAKLAAARRKLHKREVAAGRTLEEFKKDVRMLQRWMDKSQEAKKEMVESNLRLVISIAKKYTNRGLSFLDLIQEGNMGLMKAVEKFEYRRGYKFSTYATWWIRQAVTRAIADQARTIRIPVHMIETINKVLRGAKKLMMETGKEPTPEELGEELGFTPDRVREIYKIAQHPISLQAEVGDGGESSFGDFLEDTAVESPAEATGYSMLKDKMKEVLKTLTDRERFVLIHRFGLLDGRPKTLEEVGSAFNVTRERIRQIEAKALRKMRHPIRSKQLRAFLDLLEEEKIGSGKIKSYKN a0a0h3mhh0_chlt2 CTL0766 protein protein chlt2 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) MYFTRDPVIETVITSREGYKLSIRNSKHLSQDPFVVEAIEVVRLGGTSFFRNCDHSKPFLLPASDYEVMEIRDAKINLKAVGLDRGVKIVGSREALLKMPKVAPIVSVSEDNTIVSEEEVVADSTVAAPASTPVAPMSKKERRKEFKNEKWKDKKKQGRRRNSKEIADAVGSSQEMIDTVAEECLQESSSEEGDFSERRFSLIPPPTRLISDGPEEPEEESQPVTSVDLNESLNALVSESCNVIESILADEDTVVFTKEKDQTAEESQEQPSLSLEETPVHDSISSEE tarp_chlt2 Translocated actin-recruiting phosphoprotein tarP CTL0716 protein protein chlt2 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) MTNSISGDQPTVTTFTSSTTSASGASGSLGASSVSTTANATVTQTANATNSAATSSIQTTGETVVNYTNSASAPTVTVSTSSSSTQATATSNKTSQAVAGKITSPDTSESSETSSTSSSDHIPSDYEPISTTENIYENIYESIDDSSTSGPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYENIYESIDDSSTSGPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYENIYESIDGSSTSDPENTSGGAAAALNSLRGSSYTTGPRNEGVFGPGPEGLPDMSLPSYDPTNKTSLLTFLSNPHVKSKMLENSGHFVFIDTDRSSFILVPNGNWDQVCSIKVQNGKTKEDLDIKDLENMCAKFCTGFNKFSGDWDSRVEPMMSAKAGVASGGNLPNTVIINNKFKTCVAYGPWNSREASSGYTPSAWRRGHQVNFGEIFEKANDFNKINWGTQAGPSSEDDGISFSNETPGAGPAAAPSPTPSSIPVINVNVNVGGTNVNIRDTNVNTTNTTPTTQSTDASTDTSDIDNINTNNQTDDINTTDKDSDGAGGVNGDISETESSSGDDSGSVSSSESDKNASVGNDGPAMKDILSAVRKHLDVVYPGDNGGSTEGPLQANQTLGDIVQDMETTGTSQETVVSPWKGSTSSTGSAGGSGSVQTLLPSPPPTPSTTTLRTGTGATTTSLMMGGPIKADIITTGGGGRIPGGGTLEKLLPRIRAHLDISFDGQGDLVSTEEPQLGSIVNKFRKETGSGGIVASVESAPGKPGSAQVLTGTGGDKGNLFQAAAAVTQALGNVAGKVNLAIQGQKLSSLVNDDGKGSVGRDLFQAATQTTQALSSLIDTVG acts_rabit Actin, alpha skeletal muscle ACTA1 ACTA Alpha-actin-1 protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF siga-grga-1 3294604 N/A 3294608 unspecified role unspecified role bait bait Strep-tag Strep-tag strep tag strep tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false ecolx Escherichia coli N/A 3294609 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false grga-siga-1 3294605 N/A 3294609 unspecified role unspecified role bait bait Strep-tag Strep-tag strep tag strep tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3294608 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 121-322 Region 121-322 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false grga-siga-2 3294606 N/A 3294609 unspecified role unspecified role bait bait Strep-tag Strep-tag strep tag strep tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3294608 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false Region 270-316 Region 270-316 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false siga-grga-2 3294607 N/A 3294609 unspecified role unspecified role prey prey Region 1-64 Region 1-64 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3294608 unspecified role unspecified role bait bait Strep-tag Strep-tag strep tag strep tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false ecolx Escherichia coli direct interaction direct interaction false false false tarp-1 3148940 N/A 3148946 unspecified role unspecified role unspecified role unspecified role Region 625-825 Region 625-825 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false acta1-tarp-1 3148942 N/A 3148949 unspecified role unspecified role unspecified role unspecified role Pyrene-label Pyrene-label pyrene label pyrene label undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false rabit Oryctolagus cuniculus (Rabbit) Rabbit N/A 3148946 unspecified role unspecified role unspecified role unspecified role Region 625-825 Region 625-825 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false acta1-tarp-2 3148943 N/A 3148949 unspecified role unspecified role unspecified role unspecified role rabit Oryctolagus cuniculus (Rabbit) Rabbit N/A 3148946 unspecified role unspecified role unspecified role unspecified role Region 726-825 Region 726-825 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false tarp-acta1-1 3148944 N/A 3148949 unspecified role unspecified role prey prey rabit Oryctolagus cuniculus (Rabbit) Rabbit N/A 3148946 unspecified role unspecified role bait bait Region 425-1005 Region 425-1005 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false acta1-tarp-3 3148945 N/A 3148949 unspecified role unspecified role unspecified role unspecified role rabit Oryctolagus cuniculus (Rabbit) Rabbit N/A 3148946 unspecified role unspecified role unspecified role unspecified role Region 425-1005 Region 425-1005 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint mirrashidi-2015-3 human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 confocal microscopy confocal microscopy anti tag immunost anti tag immunostaining anti tag immunost Mirrashidi KM., Elwell CA., Verschueren E., Johnson JR., Frando A., Von Dollen J., Rosenberg O., Gulbahce N., Jang G., Johnson T., Jäger S., Gopalakrishnan AM., Sherry J., Dunn JD., Olive A., Penn B., Shales M., Cox JS., Starnbach MN., Derre I., Valdivia R., Krogan NJ., Engel J., Mirrashidi KM., Elwell CA., Verschueren E., Johnson JR., Frando A., Von Dollen J., Rosenberg O., Gulbahce N., Jang G., Johnson T., Jäger S., Gopalakrishnan AM., Sherry J., Dunn JD., Olive A., Penn B., Shales M., Cox JS., Starnbach MN., Derre I., Valdivia R., Krogan NJ., Engel J. jengel@medicine.ucsf.edu, Nevan.Krogan@ucsf.edu Cell host & microbe 2015 Only protein-protein interactions imex curation imex curation mital-2015-4 human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 fluorescence imaging fluorescence microscopy fluorescence imaging tag visualisation tag visualisation Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T., Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T. Ted_Hackstadt@NIH.Gov Biochemical and Biophysical Research Communications 2015 Only protein-protein interactions imex curation imex curation mital-2015-1 yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T., Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T. Ted_Hackstadt@NIH.Gov HeLa cDNA Biochemical and Biophysical Research Communications 2015 Only protein-protein interactions imex curation imex curation mital-2015-2 yeast Saccharomyces cerevisiae Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T., Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T. Ted_Hackstadt@NIH.Gov Biochemical and Biophysical Research Communications 2015 Only protein-protein interactions imex curation imex curation mital-2015-3 human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T., Mital J., Lutter EI., Barger AC., Dooley CA., Hackstadt T. Ted_Hackstadt@NIH.Gov Biochemical and Biophysical Research Communications 2015 Only protein-protein interactions imex curation imex curation dylt1_human Dynein light chain Tctex-type 1 T-complex testis-specific protein 1 homolog Protein CW-1 DYNLT1 TCTEL1 TCTEX1 TCTEX-1 protein protein human Homo sapiens Human MEDYQAAEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI a0a0h3mbg2_chlt2 CTL0223 protein protein chlt2 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) MGFGTVRGKGKAVKSFFLRPLQNLEVGLFSLPIVLLLGEIGCVSSISSVSLVAVLSIVGVFVALVSFFRSWGYGLSVVGAIFFGLALCNNFPVSVFWGGLLTVSFIISYGILLLSVSLVEGHIKEKAVSLSELTASHNSLQDSYNREVQERKEKELLAQSKITALEQELSVSHEQLQEVSRKYTHTSEDLQILIDQRDSWLKDYMTLHQEYVRVVAGDEENVIFPWKVFQGNSEKDSGYQQRVQDAEHKIAHLEKLCEEENSGKRYAEECLDKALADLLESTRLREILEKEIFQKDEEIASLKQEIAAEKLLSSSVSDDRAAYKGKYLQLREQFTVKDSFLKKARRERFLAQEQLLVLKRAKEEEALNLSTTDSFSIIQNLLLQIEALEEEVTYLEELVLHNQNR inca_chltr Inclusion membrane protein A incA CT_119 protein protein chltr chltr MTTPTLIVTPPSPPAPSYSANRVPQPSLMDKIKKIAAIASLILIGTIGFLALLGHLVGFLIAPQITIVLLALFIISLAGNALYLQKTANLHLYQDLQREVGSLKEINFMLSVLQKEFLHLSKEFATTSKDLSAVSQDFYSCLQGFRDNYKGFESLLDEYKNSTEEMRKLFSQEIIADLKGSVASLREEIRFLTPLAEEVRRLAHNQQSLTVVIEELKTIRDSLRDEIGQLSQLSKTLTSQIALQRKESSDLCSQIRETLSSPRKSASPSTKSS ince_chltr Inclusion membrane protein E incE CT_116 protein protein chltr chltr MECVKQLCRNHLCLDSLTGPVRSVLTQGTTAEKVQLVVSCLGVVCSIICLALGIAAAAVGVSCSGFAIGLGVIAILLGIVLFAISALDVLEDHGLVGCPFKLPCKSSPANEPTVQFFKGKNGSADKVILVTQ snx1_human Sorting nexin-1 SNX1 protein protein human Homo sapiens Human MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNGSKENGIHEEQDQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS snx2_human Sorting nexin-2 Transformation-related gene 9 protein SNX2 TRG9 protein protein human Homo sapiens Human MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA snx6_human Sorting nexin-6 TRAF4-associated factor 2 SNX6 protein protein human Homo sapiens Human MMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT ince_chlt2 Inclusion membrane protein E incE CTL0371 protein protein chlt2 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) MECVKQLCRNHLRLDNLTDPVRSVLTKGTTAEKVQLAACCLGVVCSIICLALGIAAAAVGVSCGGFALGLGIIAILLGIVLFATSALDVLENHGLVGCPFKLPCKSSPANEPAVQFFKGKNGSADQVILVTQ snx5_mouse Sorting nexin-5 Snx5 protein protein mouse Mus musculus Mouse MAAVPELLEQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLSTFQSPEFSVTRQHEDFVWLHDTLTETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSTHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFSGVKEVDDFFEQEKNFLINYYNRIKDSCAKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAETHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN snx5-ince-1 3649617 N/A 3649913 unspecified role unspecified role neutral component neutral component subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level N/A 3649980 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell flag tag flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false N/A 3649916 tag fluorescence tag visualisation by fluorescence tag fluorescence unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell gfp tag gfp tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false binding region binding region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false colocalization colocalization false false false sf4c ince-snx5-3 3649617 N/A 3649980 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell flag tag flag tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false N/A 3649916 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell colocalization colocalization false false false F5A ince-snx1-1 3649617 N/A 3649916 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell N/A 3649915 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization false false false f5A sf5 ince-snx1-2 3649617 N/A 3649916 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell N/A 3649913 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization false false false f5A sf5 ince-snx2-1 3649617 N/A 3649916 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell N/A 3649914 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization false false false F5A ince-snx1-3 3649617 N/A 3649916 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell N/A 3649908 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell colocalization colocalization false false false sf5a ince-snx5-4 3649617 N/A 3649913 unspecified role unspecified role neutral component neutral component subcellular prep subcellular preparation subcellular prep physiological level physiological level endogenous level endogenous endogenous endogenous level N/A 3649915 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell N/A 3649916 tag fluorescence tag visualisation by fluorescence tag fluorescence unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell colocalization colocalization false false false sf5b sf5c nocodazole ince-snx6-3 3649617 N/A 3649981 unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell N/A 3649913 unspecified role unspecified role neutral component neutral component physiological level physiological level endogenous level endogenous endogenous endogenous level fixed cell fixed cell colocalization colocalization false false false f6d f6e We also observed increased SNX6 recruitment and SNX6-positive tubules in C. trachomatis serovar L2 transformed with a vector expressing untagged IncE (pIncE) under control of its native promoter compared to C. trachomatis transformed with empty vector (Figure 6D and 6E). a0a0h3mbg2_chlt2-dynlt1-3 3932806 N/A 3932810 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell gfp tag gfp tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false N/A 3932811 immunostaining immunostaining unspecified role unspecified role neutral component neutral component infection infection fixed cell fixed cell colocalization colocalization false false false f3 a0a0h3mbg2_chlt2-dynlt1-4 3932806 N/A 3932810 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell gfp tag gfp tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false N/A 3932811 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell mcherry tag mcherry tag mcherry mcherry fluorescent protein tag mcherry c-term range C-terminal range c-term range c-term range C-terminal range c-term range false colocalization colocalization false false false f2a a0a0h3mbg2_chlt2-1 3932807 N/A 3932810 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell N/A 3932811 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell physical association physical association false false false nfa a0a0h3mbg2_chlt2-dynlt1-1 3932808 N/A 3932810 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell N/A 3932811 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell physical association physical association false false false f1a a0a0h3mbg2_chlt2-dynlt1-2 3932809 N/A 3932810 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed living cell living cell gfp tag gfp tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false N/A 3932811 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed living cell living cell mcherry tag mcherry tag mcherry mcherry fluorescent protein tag mcherry c-term range C-terminal range c-term range c-term range C-terminal range c-term range false physical association physical association false false false f2b