DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ thakur-2008-4 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250265X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions imex curation thakur-2008-7 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250266X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions imex curation thakur-2008-12 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. DIP original experiment: DIP-250264X Nature 2008 IMEx A nuclear receptor-like pathway regulating multidrug resistance in fungi. Thakur JK., Arthanari H., Yang F., Pan SJ., Fan X., Breger J., Frueh DP., Gulshan K., Li DK., Mylonakis E., Struhl K., Moye-Rowley WS., Cormack BP., Wagner G., Näär AM. Only protein-protein interactions imex curation med15_yeast Mediator of RNA polymerase II transcription subunit 15 YOL051W GAL11 RAR3 SPT13 ABE1 MED15 SDS4 Mediator complex subunit 15 Transcription regulatory protein GAL11 Basal expression activator protein 1 Autonomous replication regulatory protein 3 Defective silencing suppressor protein 4 Ty insertion suppressor protein 13 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSAAPVQDKDTLSNAERAKNVNGLLQVLMDINTLNGGSSDTADKIRIHAKNFEAALFAKSSSKKEYMDSMNEKVAVMRNTYNTRKNAVTAAAANNNIKPVEQHHINNLKNSGNSANNMNVNMNLNPQMFLNQQAQARQQVAQQLRNQQQQQQQQQQQQRRQLTPQQQQLVNQMKVAPIPKQLLQRIPNIPPNINTWQQVTALAQQKLLTPQDMEAAKEVYKIHQQLLFKARLQQQQAQAQAQANNNNNGLPQNGNINNNINIPQQQQMQPPNSSANNNPLQQQSSQNTVPNVLNQINQIFSPEEQRSLLQEAIETCKNFEKTQLGSTMTEPVKQSFIRKYINQKALRKIQALRDVKNNNNANNNGSNLQRAQNVPMNIIQQQQQQNTNNNDTIATSATPNAAAFSQQQNASSKLYQMQQQQQAQAQAQAQAQAQAQAQAQAQAAQAAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAHAQHQPSQQPQQAQQQPNPLHGLTPTAKDVEVIKQLSLDASKTNLRLTDVTNSLSNEEKEKIKMKLKQGQKLFVQVSNFAPQVYIITKNENFLKEVFQLRIFVKEILEKCAEGIFVVKLDTVDRLIIKYQKYWESMRIQILRRQAILRQQQQMANNNGNPGTTSTGNNNNIATQQNMQQSLQQMQHLQQLKMQQQQQQQQQQQQQQQQQQQQQQQHIYPSSTPGVANYSAMANAPGNNIPYMNHKNTSSMDFLNSMENTPKVPVSAAATPSLNKTINGKVNGRTKSNTIPVTSIPSTNKKLSISNAASQQPTPRSASNTAKSTPNTNPSPLKTQTKNGTPNPNNMKTVQSPMGAQPSYNSAIIENAFRKEELLLKDLEIRKLEISSRFKHRQEIFKDSPMDLFMSTLGDCLGIKDEEMLTSCTIPKAVVDHINGSGKRKPTKAAQRARDQDSIDISIKDNKLVMKSKFNKSNRSYSIALSNVAAIFKGIGGNFKDLSTLVHSSSPSTSSNMDVGNPRKRKASVLEISPQDSIASVLSPDSNIMSDSKKIKVDSPDDPFMTKSGATTSEKQEVTNEAPFLTSGTSSEQFNVWDWNNWTSAT 275C78721B5415C7 q6fut5_canga Mediator of RNA polymerase II transcription subunit 15 GAL11B CAGL0F00803g protein protein canga Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) Yeast Torulopsis glabrata MSLDVSVRERTRNMNQLMRILMDINHLNGGDSGVLEKLRLSARNFESAIYEKSSTKQEYMASMREKIEGMQQTLQQKKHTPATPSQQVPPPQQQQQQQGSQPRITLTPQQQQLLLSKMQLAVIPQQLLSKIPNLPAGVSTWKDVTELASKNMLDQRTMEIVRGVYKVHQQLLLKASFEQQRKRQPPQQQQPQQPQQQQQQQQQQQQQQQQQQQQQQSPQNVTNGNLFHILLRLFQDEFLSSKYQEQLSKLFKMEEIKHIIQQAIEVGKKYATQRYQLGHMLTNEERVVFFKKFLNHVILKKMEETKGSNKTDATMMNLTDNHTQMGTGQESTVPQQFNTDQVISNNQMPVNNFNMNMNNNQMPQQPFQQQMPQLTLQQQQNLFQQQLQQQQQQQQQQQQQQQQAQIQAQQQQQQQQQQQQQQQQQQQQQQQLLMQNLAATKLDIEEIRNISMKAAKLQLQLTDLTNTLTNEEKDAIRSRLKTNQKLFVQVSNFAPQVYMMTKSKNFLKEVFQLRIFVKEILEKCANGIFVVKLETVDKLIMKYQRYWDSMRVQLLRRQSQTKQQEIQGALQQMQRVEAQNNNNNNNYNNNNNNNSTNNNTNNNPQMPNLNNSNIITNFSTPFQVPIATPNNITNAVKKESRKPSVSASNASTPGTTSGKAKPKSRSNRQNSRSNSINEVSSDSTKQPQTTEAVSKEEAAKIHEANVRKSEILSRFKHRQKLFITSPADLFLSTLGDCLGLKCEEIETSYKIPKNMADFINGVKISKTEQRIRTQDTVVTSVVDNKLLMQSKTGGDKRTYGIDPAALSAVFKGVQGTTNMNTLQLFSSSSLSPVTEENA C578A30B903526C1 q66wf3_cangb PDR1 AO440_000017 protein protein cangb Candida glabrata Yeast Torulopsis glabrata MQTLETTSKSNPGEVKAQKPSTRRTKVGKACDSCRRRKIKCNGLKPCPSCTIYGCECTYTDAKSTKNLKSNDAGKPKPTGRVSKNKETTRIDKDIRKSEQQYVPINANIHVGPRFPSENILNGYPQCGAPQNNVVGNPLAVNPQCHRGLSETPMSSTFKESNLRDDRLLQSSDTDDMRNGDSEERDLKGSDSENVKSKDNKSDPLIIYKDDTHIESTVNKLTQAVNELKSLQNAPSSIKSSIDAIELQLRNILDNWKPEVDFEKAKINESATTKSLETNLLRNKYTNHVHLTRFRIWIDYKNANKNNHFMGECGFSLAESFFASNQPLVDELFGLYSQVEAFSLQGLGYCVHLYEPYMKTEEAIKLMKETLYIILRFIDICVHHINEESISIANPLETYLRKKHLMPMTPTPRSSYGSPQSASTKSLVSKIIERIPQPFIESVTNVSSLQLLDLRDDESKMFGTLLNMCKSIRRKFDSVMSDYDSIVTEKSEGEQNDGKVTVAEFTSLCEAEEMLLALCYNYYNLTLYSFFEFGTNIEYMEHLLLLLEEQLALDEYYGFEKVLNVAVANAKKMGFHRWEFYVGYEESTAEKRRLLWWKLYNYEKASTMKKGFFSVIDDATVNCLLPKIFRNFGYLDRVEFLENIQKPMDLSVFSDVPISVLCKYGELALTIVTSEFHEKFLYADRYTSIRNSAKPPTLKNQLIKEIVDGIAYTETSYEAIRKQTAKLWDIALGKVTKDKINKEDTAAASKFTLSYEYHRFRLINMADNLIARLMVKPKSDWLISVMKGHLNRLYEHWKVMNEIILSMDNDYSIATTFEYYAPSCLCLATQTFLIVRNMEMDDVKMMVAVYKRFLNLGMFLQSAKVCSLADSHTFRDFSRSFSFITIISRLMIIEFMQIKELTKVEFIEKFSEVCPDLADLPPMLLDPNSCLYFSLLQQIKKSGFTLSFKKILEDARMMDFNYDRNLDSEAIKKCNGEFSKSMPSCTNVSDTTTAVSDNSAKKKASMGSARVNSTDTLTASPLSGLRNQTQLDSKDSVPSLEAYTPIDSVSDVPTGEINVPFPPVYNQNGLDQQTTYNLGTLDEFVNKGDLNELYNSLWGDLFSDVYL med15_canga Mediator of RNA polymerase II transcription subunit 15 GAL11 MED15 Mediator complex subunit 15 Transcription regulatory protein GAL11 CAGL0H06215g protein protein canga Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) Yeast Torulopsis glabrata MSSKETIPMHQRSQNVAELLTVLMDINKINGGDSTTAEKMKVHAKSFEAALFEKSSSKEEYQKTMKSKIDAMRSTRDKRKRESVGSASMMANLGQDGTNNNNNNNNNNNNNLNMAASFMGGDMFGRNQSPAQNSNANTNLNTNVGPGVNGPNGNDGTANPQMFMNQQAQARQQAAARQLKNRQMGGSSAQQQQLTQQQQQLLNQMRVAPIPKELLQRIPNLPPGVTTWEQVTALAQQNRLSAQDMSIAKDIYKIHQQYLIKAKLQQQQQRQQQQRQQGNPDVNNNMAGSNNNNNNNLPMAQQQMQQRQQQQQQSQQQQNRNPNQRHNVLSQINQMFTADEQRALLQEAMEACKNFQKTHFGGQMSDANKQAFIKKFINSKALKKLEAMRMAQGGNNNANLNKGQADMLQRQQANMQMNQQQQRAAQNQRRGPVMNDAVSQGYNNQMNSAADSTMNNSNQPMNIGNNGVNMIPNQSQQQQQTNRPKEQTPQQPQQRIQSNRSVPMLNPTPEDVEVVRRISAEAAKTQLRLTDLTNSLTPQERDEIKKRLQKNQQLFAQVSSYAPQVYLFTKSESFLKEVLQLRIFIKEILEKCSKGIYVVKLDTVDKLVIKYQKYWESMKIQLLRRQQLLQQQQQQQQQGMDPNRAQNSQQQQQQNQANMQQARNRKPTKNQTTPAIAASVAMNMNDKGASMSPALQKAGSAVPNFAQQMSPNMTPGTIPPTNVLSPHSQSHIPMVSPTMAKAASAAALKNDTASSSRRGSTKPRGKSTAPVTGKKTSNAPTPQVVPATVPSTTNLSAAGTPNIRNKSATPLTAGLSPKSTIRSNSNTALASAKTPSPMTVSIPQPGNSSVFKKEEEYLSKLQLRKEEIRFRQKQRLDILSSSPVDLFLTTVADCLGINDEEIELINKIPETTADNINNTGKKKLTKAAQKLRDKEILNVSIQVGEKDKLIMSSKAPDKVMDYSISAMSLAAVFKNLSSTGSLNNIALSGSNATTSKDIGNIYSHTGGVKRKFDEVEISPNSNGSPSASIMSESKKIKIDSPEDMFVTHSSEAAKGTNNSSLMDSGKEGSCKSMAGSATEVNDTSIWDWNFWTSIE 903F3DF1ADC85348 cggal11bp-pdr1-1 3170160 N/A 3170176 unspecified role unspecified role bait bait Region 1-77 Region 1-77 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3170177 unspecified role unspecified role prey prey Region 1074-1104 Region 1074-1104 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false in vitro In vitro direct interaction direct interaction false false false pdr1-1 3170163 N/A 3170174 unspecified role unspecified role prey prey Region 1-100 Region 1-100 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3170177 unspecified role unspecified role prey prey Region 1074-1104 Region 1074-1104 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false in vitro In vitro direct interaction direct interaction false false false cggal11ap-pdr1-1 3170168 N/A 3170178 unspecified role unspecified role bait bait Region 1-79 Region 1-79 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3170177 unspecified role unspecified role prey prey Region 1074-1104 Region 1074-1104 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false in vitro In vitro direct interaction direct interaction false false false