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    <entry>
        <source releaseDate="2022-02-04Z">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3140915">
                <names>
                    <shortLabel>pazhouhandeh-2006-5</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="16446454" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-262938X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23416" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15566207" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0510784103" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="4932">
                        <names>
                            <shortLabel>yeasx</shortLabel>
                            <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>2 hybrid</shortLabel>
                        <fullName>two hybrid</fullName>
                        <alias typeAc="MI:0303" type="go synonym">2H</alias>
                        <alias typeAc="MI:0303" type="go synonym">2h</alias>
                        <alias typeAc="MI:0303" type="go synonym">Gal4 transcription regeneration</alias>
                        <alias typeAc="MI:0303" type="go synonym">two-hybrid</alias>
                        <alias typeAc="MI:0303" type="go synonym">yeast two hybrid</alias>
                        <alias typeAc="MI:0303" type="go synonym">2-hybrid</alias>
                        <alias typeAc="MI:0303" type="go synonym">classical two hybrid</alias>
                        <alias typeAc="MI:1041" type="synonym">classical two hybrid</alias>
                        <alias typeAc="MI:1041" type="synonym">2H</alias>
                        <alias typeAc="MI:1041" type="synonym">two-hybrid</alias>
                        <alias typeAc="MI:1041" type="synonym">2-hybrid</alias>
                        <alias typeAc="MI:1041" type="synonym">Gal4 transcription regeneration</alias>
                        <alias typeAc="MI:1041" type="synonym">2h</alias>
                        <alias typeAc="MI:1041" type="synonym">yeast two hybrid</alias>
                        <alias typeAc="MI:1041" type="synonym">Y2H</alias>
                        <alias typeAc="MI:1041" type="synonym">Y-2H</alias>
                        <alias typeAc="MI:1041" type="synonym">2 hybrid</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0018" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-94" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="12634794" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="1946372" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="10967325" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Pazhouhandeh M., Dieterle M., Marrocco K., Lechner E., Berry B., Brault V., Hemmer O., Kretsch T., Richards KE., Genschik P., Ziegler-Graff V.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-262938X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2006</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">F-box-like domain in the polerovirus protein P0 is required for silencing suppressor function.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Pazhouhandeh M.,  Dieterle M.,  Marrocco K.,  Lechner E.,  Berry B.,  Brault V.,  Hemmer O.,  Kretsch T.,  Richards KE.,  Genschik P.,  Ziegler-Graff V.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"></attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3140922">
                <names>
                    <shortLabel>q8jz12_9viru</shortLabel>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q8JZ12" version="TrEMBL_12" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-45368N"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_840095.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016032" secondary="viral process" version="TrEMBL_35"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-848667" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006755" version="TrEMBL_35"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="12042">
                    <names>
                        <shortLabel>beewe</shortLabel>
                        <fullName>Beet western yellows virus</fullName>
                    </names>
                </organism>
                <sequence>MLFETYNHILIFRANRFLTAGERILNTAEFLIAYLILFVKHDNANVNIFLARLPLLLSEQLQGDFRYVPGRRQRHRLARLHKACGASLHSSGAVNLRLPPTQDVAGLFLARNASRSMGERIHKHQDLLAKGKDEFDRFLSVWCADAERSLSQTSKVCAERDNVCVELINLGFALRALVLDPRVHCRSAYARVALCVYRIYGEDSGLDFWRLANFPLQCWPYHIEKHFTGSVVQKILQM</sequence>
            </interactor>
            <interactor id="3140921">
                <names>
                    <shortLabel>cul1_arath</shortLabel>
                    <fullName>Cullin-1</fullName>
                    <alias typeAc="MI:0301" type="gene name">CUL1</alias>
                    <alias typeAc="MI:0305" type="locus name">At4g02570</alias>
                    <alias typeAc="MI:0306" type="orf name">T10P11.26</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q94AH6" version="SP_50" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006511" secondary="ubiquitin-dependent protein catabolic process" version="SP_147"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001031575.1"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.3" version="SP_147" refType="transcript"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.2" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000794" secondary="condensed nuclear chromosome" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005819" secondary="spindle" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036388" version="SP_147"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.3" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009867" secondary="jasmonic acid mediated signaling pathway" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009524" secondary="phragmoplast" version="SP_147"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O22770" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001373" version="SP_147"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.4" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048366" secondary="leaf development" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016567" secondary="protein ubiquitination" version="SP_147"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.4" version="SP_147" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042752" secondary="regulation of circadian rhythm" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036390" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016157" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009793" secondary="embryo development ending in seed dormancy" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009734" secondary="auxin-activated signaling pathway" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019559" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009753" secondary="response to jasmonic acid" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_147"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.1" version="SP_147" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004842" secondary="ubiquitin-protein transferase activity" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007049" secondary="cell cycle" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009873" secondary="ethylene-activated signaling pathway" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016158" version="SP_147"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q56W31" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036317" version="SP_147"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_567243.1"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570" version="SP_147" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010087" secondary="phloem or xylem histogenesis" version="SP_147"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001190661.1"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.1" version="SP_147" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblplants" id="AT4G02570.2" version="SP_147" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_147"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031461" secondary="cullin-RING ubiquitin ligase complex" version="SP_147"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001031576.1"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-532411" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33346N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009733" secondary="response to auxin" version="SP_147"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016159" version="SP_147"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="3702">
                    <names>
                        <shortLabel>arath</shortLabel>
                        <fullName>Arabidopsis thaliana (Mouse-ear cress)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse-ear cress</alias>
                    </names>
                </organism>
                <sequence>MERKTIDLEQGWDYMQTGITKLKRILEGLNEPAFDSEQYMMLYTTIYNMCTQKPPHDYSQQLYDKYREAFEEYINSTVLPALREKHDEFMLRELFKRWSNHKVMVRWLSRFFYYLDRYFIARRSLPPLNEVGLTCFRDLVYNELHSKVKQAVIALVDKEREGEQIDRALLKNVLDIYVEIGMGQMERYEEDFESFMLQDTSSYYSRKASSWIQEDSCPDYMLKSEECLKKERERVAHYLHSSSEPKLVEKVQHELLVVFASQLLEKEHSGCRALLRDDKVDDLSRMYRLYHKILRGLEPVANIFKQHVTAEGNALVQQAEDTATNQVANTASVQEQVLIRKVIELHDKYMVYVTECFQNHTLFHKALKEAFEIFCNKTVAGSSSAELLATFCDNILKKGGSEKLSDEAIEDTLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRSANDDHERSILTKLKQQCGGQFTSKMEGMVTDLTLARENQNSFEDYLGSNPAANPGIDLTVTVLTTGFWPSYKSFDINLPSEMIKCVEVFKGFYETKTKHRKLTWIYSLGTCHINGKFDQKAIELIVSTYQAAVLLLFNTTDKLSYTEILAQLNLSHEDLVRLLHSLSCAKYKILLKEPNTKTVSQNDAFEFNSKFTDRMRRIKIPLPPVDERKKVVEDVDKDRRYAIDAAIVRIMKSRKVLGHQQLVSECVEQLSRMFKPDIKAIKKRMEDLITRDYLERDKENPNMFRYLA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-23416-5" id="3140938">
                <names>
                    <shortLabel>q8jz12_9lute-cul1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-197466E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15566218" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23416-5" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3140915</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3140939">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15566223" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3140922</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="4932">
                                <names>
                                    <shortLabel>yeasx</shortLabel>
                                    <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3140940">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15566222" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3140921</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="4932">
                                <names>
                                    <shortLabel>yeasx</shortLabel>
                                    <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
