IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ liu-2020-1 human-tpc-1 Human Thyroid gland papillary carcinoma Human tpc-1 TPC-1;Thyroid gland papillary carcinoma Cellosaurus TPC-1 (CVCL_6298) mirna interference luciferase assay miRNA interference luciferase reporter assay miRNA interference luciferase assay tag luciferase tag visualisation by luciferase assay tag luciferase Liu S., Zhang D., Chen L., Gao S., Huang X. xiuhuang111@sina.com Oncology letters 2020 Only protein-protein interactions imex curation imex curation hsa-mir-331-3p mirna micro rna micro RNA micro-RNA micro-rna mirna miRNA human Homo sapiens Human GCCCCUGGGCCUAUCCUAGAA lnc_linc0003 LincR-003 (LINCR-0003), long non-coding RNA, lncBRM lncrna long non-coding ribonucleic acid lncRNA long non coding RNA long non coding ribonucleic acid long non-coding RNA lncrna human Homo sapiens Human AUACAUAAGCACUUCCUUGUGAGCUGGAAGGAAAAUGACUGAAAAAAAUUAUGAGACUUUGGCCUUGAAAGUCUCAUAGUGAGUGCCUGUCAUGUUAUAACAGGGCAAAAACUGGCUGCUCUCCUCUACAUUCGGUGGCCUUGGGAACACCAAAGAUGUGGCCUUGGCAACACUUGCACAUCGAGGUCAAGAGGCCAGGAAGAGCAUCCUGCCUUCUAACUCCUUUGAAGUUUACUCAAAAUUCUCAUCCUGAACUGGACUUUUGGACUCAACAACAAAAGGGAUGACGCUGUGUUUCAGAGGAAUUCAUAAGCAGAAUUGAAUUUGUUUUAGUUAACUCCUUAUUUGAUUGGAAUAUUGUCGACUUAACAAAAUAGUAGAAAGAGCAUUGGGCUGAAGUGAGAAGAUUUGAAUUCUAGUCCAAAAUCUGUUACUAACCAGCUCUUUGACCCUGAGAAGUCAUUUGACUUGAAUUAUAGUCUUUUUCUUAUAUGGGAAAGGUGGAGUAUACUCAGAGUCUCUCCUAAGUGCUAAGAUUCUGUGAUUCUAUGAAAUCAGACCAUCAGAGAGGAAUACUGCAGUGUUCUCCUGCAUGGGUUGUAAAUGAGAAAAAAGAAAGAAGGAGAGCAAAAUGACUUAAAGACAUUUUCAAGAAAAAAAGAGGAGAGAAGUCACUGAAAUGGAAAAAUAAACAUAUUAUAUAACUAUUUAUUGCACUAUGCAAUAAAAACAUCUUCAGCAACAGCCACACAAGUGCGGGUAGAGGGUCUGCUUUGAAGAGAGAAAAAAGGCUGCUGCAGAAAAAACAAACCUCAAUUCAUAAUUGGAGCUUUUGUUCUUUCUGGAUUGUUUUGUGAAGAACAUGCUGCCAAAAAACAUUUUUCUUCUGUAACCGCUUCUUUUGAAACUCCAUUCUUUUUUAUUUCAAGGAUGUUUAUUAUCUACUCAUUUCUUUUUAUUUAUUUUUGAAUCAUAUACCCCAAUGUCUAGAUGACUGGGACCACUAGGUUUCAUAUUUCCCAGAUGAGAUUAGUUGUACAGUUCAUUUUGCAGGUUUAUUCAGAGCAUUUCAAUGGCAUUUCACCUACAGUUCACCUAUAUUGAGUCCUAAGAAAUUGAAGGUGUUUCUUGAUAGUUCUCCUGCUCCAUCUUCUUCCAGGGGAUUGAUUUGGCUUCUUAUGUUUUUGUAUUUGGUUGCUCAUUAGAGAUAAGCCUGAUUAUUUGGCAUUGUGUAUUUUCUCUGUUUUAAAAAGGGAAAAUACAACAUGUUAUUAAUUAUUAUGAUAUAAUAAAAAAUGGAGAGAAGGAAAAAAAAAAAAAA mrna_slc25a1 solute carrier family 25 member 1, mRNA mrna messenger rna mRNA mrna human Homo sapiens Human GAGCGCGGAGTTCTGGAGTCTCGGACCCGAAGCCGCCACAGGGCGCCCCGCCTCCCGCCCGCCATGCCCGCGCCCCGCGCCCCGCGCGCTCTGGCGGCCGCCGCGCCCGCGTCCGGGAAGGCCAAGCTGACGCACCCGGGGAAGGCGATCCTGGCAGGCGGCCTGGCGGGTGGCATCGAGATCTGCATCACCTTCCCCACCGAGTACGTGAAGACGCAGCTGCAGCTGGACGAGCGCTCGCACCCGCCGCGGTACCGGGGCATCGGGGACTGCGTGCGGCAGACGGTTCGCAGCCATGGCGTCCTGGGCCTGTACCGCGGCCTTAGCTCCCTGCTCTACGGTTCCATCCCCAAGGCGGCCGTCAGGTTTGGAATGTTCGAGTTCCTCAGCAACCACATGCGGGATGCCCAGGGACGGCTGGACAGCACGCGTGGGCTGCTGTGCGGCCTGGGCGCTGGCGTGGCCGAGGCCGTGGTGGTCGTGTGCCCCATGGAGACCATCAAGGTGAAGTTCATCCACGACCAGACCTCCCCAAACCCCAAGTACAGAGGATTCTTCCACGGGGTTAGGGAGATTGTGCGGGAACAAGGGCTGAAGGGGACGTACCAGGGCCTCACAGCCACTGTCCTGAAGCAGGGCTCGAACCAGGCCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCAACAAGCCCATGAACCCTCTGATCACTGGGGTCTTCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTAAGACCCGGATGCAGGGCCTGGAGGCGCACAAATACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCATTCTACAAGGGCACTGTCCCCCGCCTGGGCCGGGTCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCAACAAAGTGTGGAAGACGGACTAAGCCTAGAGAGGCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGATTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCCACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTCCCCCCTGTGGTCTGTGTGTGACACCACCACTGTGTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCCTGTGTTTCATGTTCTGTGTCACGTGACCCTGTGCCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCGGTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGCCTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGCCCCCTGCTTCTCCCGCCATTGGCCTTAACTGGCCCTCGGGCCCTCTCTCCGCCCCGGACAGGGTGGCACCCACCACTCTCAGGACCACCCTGCCAAGGCAGAATAAACCGGATCCTGTTGCA hsa_mir_331_3p-lnc_linc0003-1 3978065 N/A 3978066 predetermined predetermined participant predetermined regulator regulator modulator regulator neutral component neutral component engineered engineered purified purified N/A 3978067 regulator target regulator target regulator target modulator target neutral component neutral component over-expressed over expressed level over-expressed living cell living cell engineered engineered tag luciferase tag luciferase tag 3' range 3' range 3' range 3' range false URS000075A45E_9606:r.1159_1162delinsaaaa mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig 3 A, B down-regulates quantity by destabilization hsa_mir_331_3p-mrna_slc25a1-1 3978065 N/A 3978066 predetermined predetermined participant predetermined regulator regulator modulator regulator neutral component neutral component engineered engineered purified purified N/A 3978068 regulator target regulator target regulator target modulator target neutral component neutral component over-expressed over expressed level over-expressed living cell living cell engineered engineered tag luciferase tag luciferase tag 3' range 3' range 3' range 3' range false ENST00000215882:r.1416_1419delinsaaaa mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig 4 A, B down-regulates quantity by destabilization