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    <entry>
        <source releaseDate="2021-10-18+01:00">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
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            <attributeList>
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                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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        <experimentList>
            <experimentDescription id="4055484">
                <names>
                    <shortLabel>wang-2019-17</shortLabel>
                </names>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-brain</shortLabel>
                            <fullName>Mus musculus brain</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>brain</shortLabel>
                                <fullName>Brain [cerebrum]</fullName>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
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                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Wang ZT., Lu MH., Zhang Y., Ji WL., Lei L., Wang W., Fang LP., Wang LW., Yu F., Wang J., Li ZY., Wang JR., Wang TH., Dou F., Wang QW., Wang XL., Li S., Ma QH., Xu RX.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Brain Disease - Neurological Diseases &amp; Disorders</attribute>
                    <attribute name="data-processing" nameAc="MI:0633">Male APP/PS1 transgenic mice that co‐express mutant human APP and PS1 (Jackson Laboratory, 004462)</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">maquanhong@suda.edu.cn;zjxuruxiang@163.com</attribute>
                    <attribute name="journal" nameAc="MI:0885">Aging cell</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2019</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="4055485">
                <names>
                    <shortLabel>disc1_mouse</shortLabel>
                    <fullName>Disrupted in schizophrenia 1 homolog</fullName>
                    <alias typeAc="MI:0301" type="gene name">Disc1</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060090" secondary="molecular adaptor activity" version="SP_130"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060998" secondary="regulation of dendritic spine development" version="SP_130"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008021" secondary="synaptic vesicle" version="SP_130"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060271" secondary="cilium assembly" version="SP_130"/>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MQGGGPRGAPIHSPSHGADSGHGLPPAVAPQRRRLTRRPGYMRSTAGSGIGFLSPAVGMPHPSSAGLTGQQSQHSQSKAGQCGLDPGSHCQASLVGKPFLKSSLVPAVASEGHLHPAQRSMRKRPVHFAVHSKNDSRQSERLTGSFKPGDSGFWQELLSSDSFKSLAPSLDAPWNKGSRGLKTVKPLASPALNGPADIASLPGFQDTFTSSFSFIQLSLGAAGERGEAEGCLPSREAEPLHQRPQEMAAEASSSDRPHGDPRHLWTFSLHAAPGLADLAQVTRSSSRQSECGTVSSSSSDTGFSSQDASSAGGRGDQGGGWADAHGWHTLLREWEPMLQDYLLSNRRQLEVTSLILKLQKCQEKVVEDGDYDTAETLRQRLEELEQEKGRLSWALPSQQPALRSFLGYLAAQIQVALHGATQRAGSDDPEAPLEGQLRTTAQDSLPASITRRDWLIREKQRLQKEIEALQARMSALEAKEKRLSQELEEQEVLLRWPGCDLMALVAQMSPGQLQEVSKALGETLTSANQAPFQVEPPETLRSLRERTKSLNLAVRELTAQVCSGEKLCSSLRRRLSDLDTRLPALLEAKMLALSGSCFSTAKELTEEIWALSSEREGLEMFLGRLLALSSRNSRRLGIVKEDHLRCRQDLALQDAAHKTRMKANTVKCMEVLEGQLSSCRCPLLGRVWKADLETCQLLMQSLQLQEAGSSPHAEDEEQVHSTGEAAQTAALAVPRTPHPEEEKSPLQVLQEWDTHSALSPHCAAGPWKEDSHIVSAEVGEKCEAIGVKLLHLEDQLLGAMYSHDEALFQSLQGELQTVKETLQAMILQLQPTKEAGEASASYPTAGAQETEA</sequence>
            </interactor>
            <interactor id="4055486">
                <names>
                    <shortLabel>mlp3a_mouse</shortLabel>
                    <fullName>Microtubule-associated proteins 1A/1B light chain 3A</fullName>
                    <alias typeAc="MI:0301" type="gene name">Map1lc3a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Autophagy-related protein LC3 A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Autophagy-related ubiquitin-like modifier LC3 A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MAP1 light chain 3-like protein 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MAP1A/MAP1B light chain 3 A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Microtubule-associated protein 1 light chain 3 alpha</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006914" secondary="autophagy" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009267" secondary="cellular response to starvation" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005543" secondary="phospholipid binding" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031090" secondary="organelle membrane" version="SP_155"/>
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                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000027602" version="SP_155" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000422" secondary="autophagy of mitochondrion" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000421" secondary="autophagosome membrane" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044754" secondary="autolysosome" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005874" secondary="microtubule" version="SP_155"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q91VR7" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010040" secondary="response to iron(II) ion" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008429" secondary="phosphatidylethanolamine binding" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070301" secondary="cellular response to hydrogen peroxide" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097352" secondary="autophagosome maturation" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000045" secondary="autophagosome assembly" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016236" secondary="macroautophagy" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005770" secondary="late endosome" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010288" secondary="response to lead ion" version="SP_155"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015630" secondary="microtubule cytoskeleton" version="SP_155"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000029128" version="SP_155" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGF</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-29004-7" id="4055487">
                <names>
                    <shortLabel>disc1-map1lc3a-1</shortLabel>
                </names>
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                </xref>
                <experimentList>
                    <experimentRef>4055484</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="4055488">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26990404" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>4055485</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="4055489">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26990403" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>4055486</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">fig. 2d</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-29004-9" id="4055490">
                <names>
                    <shortLabel>disc1-map1lc3a-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-26990406" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-29004-9" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>4055484</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="4055491">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26990409" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>4055485</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="4055492">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26990408" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>4055486</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">fig. 2d</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
