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    <entry>
        <source releaseDate="2021-03-15Z">
            <names>
                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
            </names>
            <bibref>
                <xref>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
                <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
                <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
                <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3975848">
                <names>
                    <shortLabel>megill-2013-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="23719799" refType="primary-reference" refTypeAc="MI:0358"/>
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                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607354" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28682" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-brain</shortLabel>
                            <fullName>Mus musculus brain</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>brain</shortLabel>
                                <fullName>Brain [cerebrum]</fullName>
                            </names>
                            <xref>
                                <primaryRef db="mint" dbAc="MI:0471" id="MINT-86295" refType="identity" refTypeAc="MI:0356"/>
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                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Megill A., Lee T., DiBattista AM., Song JM., Spitzer MH., Rubinshtein M., Habib LK., Capule CC., Mayer M., Turner RS., Kirkwood A., Yang J., Pak DT., Lee HK., Hoe HS.</attribute>
                    <attribute name="dataset" nameAc="MI:0875">Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">hh69@georgetown.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">The Journal of neuroscience : the official journal of the Society for Neuroscience</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2013</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3975849">
                <names>
                    <shortLabel>rgrf1_mouse</shortLabel>
                    <fullName>Ras-specific guanine nucleotide-releasing factor 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Guanine nucleotide-releasing protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ras-specific nucleotide exchange factor CDC25</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CDC25Mm</alias>
                    <alias typeAc="MI:0301" type="gene name">Rasgrf1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cdc25</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Grf1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P27671" version="SP_75" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000048" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001331" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035899" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034976" secondary="response to endoplasmic reticulum stress" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2IJE" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" secondary="neuronal cell body" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023578" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000651" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000034912" version="SP_196" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097440" secondary="apical dendrite" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016327" secondary="apicolateral plasma membrane" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036964" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048167" secondary="regulation of synaptic plasticity" version="SP_196"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P27671" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035020" secondary="regulation of Rac protein signal transduction" version="SP_196"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-645522" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005085" secondary="guanyl-nucleotide exchange factor activity" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046579" secondary="positive regulation of Ras protein signal transduction" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030745" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090630" secondary="activation of GTPase activity" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019804" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011993" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008937" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031175" secondary="neuron projection development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048168" secondary="regulation of neuronal synaptic plasticity" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001849" version="SP_196"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_035375.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000032356" version="SP_196" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031267" secondary="small GTPase binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035023" secondary="regulation of Rho protein signal transduction" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5673001" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035254" secondary="glutamate receptor binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" secondary="protein C-terminus binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043547" secondary="positive regulation of GTPase activity" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000034912" version="SP_196" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046578" secondary="regulation of Ras protein signal transduction" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030426" secondary="growth cone" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000219" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030971" secondary="receptor tyrosine kinase binding" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001895" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048146" secondary="positive regulation of fibroblast proliferation" version="SP_196"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-41194N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007264" secondary="small GTPase mediated signal transduction" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000310" secondary="regulation of NMDA receptor activity" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" secondary="cell population proliferation" version="SP_196"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MQKAIRLNDGHVVTLGLLAQKDGTRKGYLSKRSADNPKWQTKWFALLQNLLFYFESDSSPRPSGLYLLEGSICKRAPSPKRGTSSKESGEKQQHYFTVNFSNDSQKTLELRTEDAKDCDEWVAAIARASYKILATEHEALMQKYLHLLQVVETEKTVAKQLRQQLEDGEVEIERLKTEVTITNLIKDNDRIQSSNKAGSADDEDSDIKKIKKVQSFLRGWLCRRKWKNIIQDYIRSPHADSMRKRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFLHQIFYQGLKARISSWPTLVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNRDFDKLLKQYEAKPDCEERTLETFLTYPMFQIPRYILTLHELLAHTPHEHVERNSLDYAKSKLEELSRIMHDEVSETENIRKNLAIERMITEGCEILLDTSQTFVRQGSLMQMSLSEKSKSSRGRLGSLSTKKEGERQCFLFSKHLIICTRGSGGKLHLTKNGVISLIDCTLLDEPENLDDEAKGAGPEIEHLEFKIGVEPKDSLPFTVILVASTRQEKAAWTSDIIQCVDNIRCNGLMMNAFEENSKVTVPQMIKSDASLYCDDVDIRFSKTMNSCKVLQIRYASVERLLERLTDLRFLSIDFLNTFLHSYRVFTNAMVVLDKLINIYRKPMSAIPARSLELLFSSSHNAKLLYGDAPKSPRASRKFSSPPPLAIGTSSPSRRRKLSLNIPIITGGKALELASLGCSSDSYANIHSPISPFGKTTLDTGKLCMASSLPKTPEEIDVPATIPEKPGELSASRKHSSDVLKEESEDDQNHSDEDNTEVSPVKSPPTPKSFLNRTITEFPFFNYNNGILMTTCRDLVDNNRSTLSATSAFAIATAGANEGPSNKEVFRRMSLANTGFSSDQRNIDKEFVIRRAATNRVLNVLRHWVTKHTQDFDTDDTLKYRVICFLEEVMHDPDLLTQERKAAANIIRTLTLEETTEQHSMLEEVILMTEGVKTEPFENHPALEIAEQLTLLDHLVFKSIPYEEFFGQGWMKAEKYERTPYIMKTTKHFNHVSNFIASEIIRNEDISARASAIEKWVAVADICRCLHNYNAVLEITSSINRSAIFRLKKTWLKVSKQTKSLLDKLQKLVSSDGRFKNLRESLRNCDPPCVPYLGMYLTDLVFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQTTYKIDPQPKVIQYLLDESFMLDEESLYESSLLIEPKLPT</sequence>
            </interactor>
            <interactor id="3975850">
                <names>
                    <shortLabel>a4_mouse</shortLabel>
                    <fullName>Amyloid-beta precursor protein</fullName>
                    <alias typeAc="MI:0301" type="gene name">App</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Alzheimer disease amyloid A4 protein homolog</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ABPP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloidogenic glycoprotein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloid precursor protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">A4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">AD1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Alzheimer disease amyloid protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloid-beta (A4) precursor protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Amyloid-beta A4 protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P12023" version="SP_117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000185" secondary="activation of MAPKKK activity" version="SP_249"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4YN0" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043393" secondary="regulation of protein binding" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905606" secondary="regulation of presynapse assembly" version="SP_249"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-3000178" version="SP_249"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-418594" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" secondary="positive regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_249"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-432720" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046914" secondary="transition metal ion binding" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905896" secondary="positive regulation of cellular response to tunicamycin" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007186" secondary="G protein-coupled receptor signaling pathway" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902894" secondary="negative regulation of pri-miRNA transcription by RNA polymerase II" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905906" secondary="regulation of amyloid fibril formation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005791" secondary="rough endoplasmic reticulum" version="SP_249"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019722" secondary="calcium-mediated signaling" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051260" secondary="protein homooligomerization" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900272" secondary="negative regulation of long-term synaptic potentiation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045931" secondary="positive regulation of mitotic cell cycle" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032930" secondary="positive regulation of superoxide anion generation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_249"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P97487" version="SP_117" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007409" secondary="axonogenesis" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051124" secondary="synaptic assembly at neuromuscular junction" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050730" secondary="regulation of peptidyl-tyrosine phosphorylation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043065" secondary="positive regulation of apoptotic process" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007189" secondary="adenylate cyclase-activating G protein-coupled receptor signaling pathway" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043204" secondary="perikaryon" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902949" secondary="positive regulation of tau-protein kinase activity" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990535" secondary="neuron projection maintenance" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034364" secondary="high-density lipoprotein particle" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903523" secondary="negative regulation of blood circulation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900181" secondary="negative regulation of protein localization to nucleus" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902961" secondary="positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" version="SP_249"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MYK" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030198" secondary="extracellular matrix organization" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061844" secondary="antimicrobial humoral immune response mediated by antimicrobial peptide" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008201" secondary="heparin binding" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048669" secondary="collateral sprouting in absence of injury" version="SP_249"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036669" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0150003" secondary="regulation of spontaneous synaptic transmission" version="SP_249"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036880" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030900" secondary="forebrain development" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090090" secondary="negative regulation of canonical Wnt signaling pathway" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055037" secondary="recycling endosome" version="SP_249"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002223" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042327" secondary="positive regulation of phosphorylation" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" secondary="positive regulation of DNA-binding transcription factor activity" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046983" secondary="protein dimerization activity" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904022" secondary="positive regulation of G protein-coupled receptor internalization" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070206" secondary="protein trimerization" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007617" secondary="mating behavior" version="SP_249"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045177" secondary="apical part of cell" version="SP_249"/>
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                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MLPSLALLLLAAWTVRALEVPTDGNAGLLAEPQIAMFCGKLNMHMNVQNGKWESDPSGTKTCIGTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHTHIVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDSVDSADAEEDDSDVWWGGADTDYADGGEDKVVEVAEEEEVADVEEEEADDDEDVEDGDEVEEEAEEPYEEATERTTSTATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVCGSVSTQSLLKTTSEPLPQDPDKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPHHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHPFGVDSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-28682-1" id="3975851">
                <names>
                    <shortLabel>app-134</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607362" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28682-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3975848</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3975852">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607364" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3975849</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3975853">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607363" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3975850</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F8A</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-28682-3" id="3975854">
                <names>
                    <shortLabel>app-rasgrf1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607366" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-28682-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3975848</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3975855">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607369" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3975849</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3975856">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-26607368" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3975850</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F8B</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
