DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ arnold-2020-2 ecoli Escherichia coli (strain K12) x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction experimental particp experimental participant identification experimental particp Arnold FM., Weber MS., Gonda I., Gallenito MJ., Adenau S., Egloff P., Zimmermann I., Hutter CAJ., Hürlimann LM., Peters EE., Piel J., Meloni G., Medalia O., Seeger MA. m.seeger@imm.uzh.ch Nature 2020 Only protein-protein interactions imex curation imex curation arnold-2020-1 ecoli Escherichia coli (strain K12) 3d-em-single electron microscopy 3D single particle reconstruction 3D-EM-single experimental particp experimental participant identification experimental particp Arnold FM., Weber MS., Gonda I., Gallenito MJ., Adenau S., Egloff P., Zimmermann I., Hutter CAJ., Hürlimann LM., Peters EE., Piel J., Meloni G., Medalia O., Seeger MA. m.seeger@imm.uzh.ch Nature 2020 Only protein-protein interactions imex curation imex curation a0a100xe85_mycth RMCT_1989 protein protein Mycobacterium thermoresistibile Mycolicibacterium thermoresistibile MIRTLLRLVPAEKRGAVAGYAVLTLLSVLLRAVGAVLLIPLLAALFSDTPSDAWLWLGWLTAVTLAGWVTDTNTARLGFDLGFAVLSRTQHDMADRLPNVAMSWFTPDNTATARQAIAATGPELAGLVVNLLTPLIGAALLPAAIGVALLFVSVPLGLAALAGVAVLFGALALSGRLSRAADKVAGETNSAFTERIIEFARTQQALRAARRVEPARSQVGSALAAQHGAGLRLLTMQIPGQVLFSLAGQVALIGFAGMAVWLTVRGQLGVPEAIALIVVLVRYLEPFAAIADLAPALETTRATLNRIQAVLDAPTLPAGRRRLDRTGAAPSIEFDDVRFSYGDEVVLDGVSFTLRPGNTTAIVGPSGSGKTTILSLIAGLQQPASGRVLLDGVDVTTLDPEARRAAVSVVFQHPYLFDGTLRDNVLVGDPEADPDDVTAAMRLARVDELLDRLPDGDATVVGEGGTALSGGERQRVSIARALLKPAPVLLVDEATSALDNANEAAVVDALTADPRPRTRVIVAHRLASIRHADRVLFVEAGRVVEDGAIDELLAAGGRFAQFWAQQQAASEWAIGSTAR a0a100xec2_mycth Mycobactin import ATP-binding/permease protein IrtA RMCT_1990 protein protein Mycobacterium thermoresistibile Mycolicibacterium thermoresistibile MARGFQGVMLRGLGARDHQATVVDKEYIAPHFVRVRLVSPTLFDEVIVEPTSWLRFWFPDPDGSDTEFQRAYTITESDPETGRFAVDMVLHEPAGPASTWARTVEPGATIAVMSMGSRGFSVPEDPEDRPVGYLLIGDSASTPAINGIIEVVPHDIPIELYLEQHHDDDVLIPLAEHPRLRVHRVSRDDASSLAAALELRDWSNWYCWAGPEAGALKQVRTRLRDEFGFPKREVYAQAYWTEGRAMGSSRGETSTPAKPAAKTAPAKAAAKPAAASGAGTPEHAAAPAAATTGAPQAAPAPGAAQPRTPVRGRWRAEAGSRLLAPLKKPLIVSGVLQALITLIELAPFVLLVELARLLLGGAEAERLWTLGLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFTRRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRVALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVIRIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIILVAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARRIQTVLDEPELVVRDRTGQAGTDHASGDQARPGTVELDRVSFEYRPGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVDGRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAARDAQIHDRITRMPDGYDSVLGAGSALSGGERQRVTIARAILADTPVLVLDEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDGRIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR a0a100xe85_mycth-a0a100xec2_mycth-2 3726987 N/A 3726989 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed ecoli Escherichia coli (strain K12) Stoichiometry: 1.0 N/A 3726990 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed 315-908 binding region 315-908 binding region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecoli Escherichia coli (strain K12) Stoichiometry: 1.0 direct interaction direct interaction false false false Fig 1, Ext Data Tab 2 a0a100xe85_mycth-a0a100xec2_mycth-3 3726987 N/A 3726990 predetermined predetermined participant predetermined structure determination identification by structure determination identification by structure determination structure determination unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed 10-255 binding region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecoli Escherichia coli (strain K12) Stoichiometry: 2.0 direct interaction direct interaction false false false Ext Data Tab 2 a0a100xe85_mycth-a0a100xec2_mycth-1 3726988 N/A 3726989 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed ecoli Escherichia coli (strain K12) Stoichiometry: 1.0 N/A 3726990 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed ecoli Escherichia coli (strain K12) Stoichiometry: 1.0 direct interaction direct interaction false false false Fig1a, Ext Data Tab1