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    <entry>
        <source releaseDate="2019-11-20Z">
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                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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        <experimentList>
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                <names>
                    <shortLabel>dasu-2010-1</shortLabel>
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                        <names>
                            <shortLabel>human-monocyte</shortLabel>
                            <fullName>Human mononuclear cells</fullName>
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                                <shortLabel>monocyte</shortLabel>
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                        <shortLabel>anti bait coip</shortLabel>
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                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Dasu MR., Devaraj S., Park S., Jialal I.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">ravi.dasu@ucdmc.ucdavis.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Diabetes care</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2010</attribute>
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                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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                <names>
                    <shortLabel>hyaluronan</shortLabel>
                    <fullName>Hyaluronan</fullName>
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                        <shortLabel>small molecule</shortLabel>
                        <fullName>small molecule</fullName>
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                        <shortLabel>chemical synthesis</shortLabel>
                        <fullName>Chemical synthesis (Chemical synthesis)</fullName>
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                    <shortLabel>tlr2_human</shortLabel>
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                    </names>
                </organism>
                <sequence>MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS</sequence>
            </interactor>
            <interactor id="3603952">
                <names>
                    <shortLabel>tlr6_human</shortLabel>
                    <fullName>Toll-like receptor 6</fullName>
                    <alias typeAc="MI:0301" type="gene name">TLR6</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9Y2C9" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4OM7" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903223" secondary="positive regulation of oxidative stress-induced neuron death" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903428" secondary="positive regulation of reactive oxygen species biosynthetic process" version="SP_191"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5603041" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035663" secondary="Toll-like receptor 2 binding" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" secondary="protein heterodimerization activity" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061809" secondary="NAD+ nucleotidase, cyclic ADP-ribose generating" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900227" secondary="positive regulation of NLRP3 inflammasome complex assembly" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071221" secondary="cellular response to bacterial lipopeptide" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043507" secondary="positive regulation of JUN kinase activity" version="SP_191"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000371376" version="SP_191" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-168188" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" secondary="amyloid-beta binding" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034150" secondary="toll-like receptor 6 signaling pathway" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034136" secondary="negative regulation of toll-like receptor 2 signaling pathway" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045429" secondary="positive regulation of nitric oxide biosynthetic process" version="SP_191"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011511915.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030670" secondary="phagocytic vesicle membrane" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_191"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006059.2"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5602498" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001774" secondary="microglial cell activation" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_191"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027187" version="SP_191"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000381950" version="SP_191" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000174130" version="SP_191" refType="gene"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011511914.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003591" version="SP_191"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-13940779" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042742" secondary="defense response to bacterium" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035355" secondary="Toll-like receptor 2-Toll-like receptor 6 protein complex" version="SP_191"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B6CH35" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071723" secondary="lipopeptide binding" version="SP_191"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011511916.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2NKL3" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001775" secondary="cell activation" version="SP_191"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000389600" version="SP_191" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017241" version="SP_191"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B6RFS4" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001611" version="SP_191"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5686938" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002224" secondary="toll-like receptor signaling pathway" version="SP_191"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000157" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007250" secondary="activation of NF-kappaB-inducing kinase activity" version="SP_191"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032675" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032717" secondary="negative regulation of interleukin-8 production" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_191"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000483" version="SP_191"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1236974" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071726" secondary="cellular response to diacyl bacterial lipopeptide" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_191"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000436693" version="SP_191" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043032" secondary="positive regulation of macrophage activation" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140052" secondary="cellular response to oxidised low-density lipoprotein particle stimulus" version="SP_191"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035897" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050135" secondary="NAD(P)+ nucleosidase activity" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035666" secondary="TRIF-dependent toll-like receptor signaling pathway" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046209" secondary="nitric oxide metabolic process" version="SP_191"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B3Y640" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_191"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005262694.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042496" secondary="detection of diacyl bacterial lipopeptide" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900017" secondary="positive regulation of cytokine production involved in inflammatory response" version="SP_191"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B6RFS5" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002755" secondary="MyD88-dependent toll-like receptor signaling pathway" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_191"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" secondary="immune response" version="SP_191"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166058" version="SP_191"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MTKDKEPIVKSFHFVCLMIIIVGTRIQFSDGNEFAVDKSKRGLIHVPKDLPLKTKVLDMSQNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVFKFNQDLEYLDLSHNQLQKISCHPIVSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSAMKLQKLDLLPIAHLHLSYILLDLRNYYIKENETESLQILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQVFIKFLSELTRGSTLLNFTLNHIETTWKCLVRVFQFLWPKPVEYLNIYNLTIIESIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLNFTQNVFTDSIFEKCSTLVKLETLILQKNGLKDLFKVGLMTKDMPSLEILDVSWNSLESGRHKENCTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIKAGDNPFQCTCELREFVKNIDQVSSEVLEGWPDSYKCDYPESYRGSPLKDFHMSELSCNITLLIVTIGATMLVLAVTVTSLCIYLDLPWYLRMVCQWTQTRRRARNIPLEELQRNLQFHAFISYSEHDSAWVKSELVPYLEKEDIQICLHERNFVPGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQRTYLQWPKEKSKRGLFWANIRAAFNMKLTLVTENNDVKS</sequence>
            </interactor>
            <interactor id="3603953">
                <names>
                    <shortLabel>hmgb1_human</shortLabel>
                    <fullName>High mobility group protein B1</fullName>
                    <alias typeAc="MI:0301" type="gene name">HMGB1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HMG1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">High mobility group protein 1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P09429" version="SP_81" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002281" secondary="macrophage activation involved in immune response" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032689" secondary="negative regulation of interferon-gamma production" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098761" secondary="cellular response to interleukin-7" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043536" secondary="positive regulation of blood vessel endothelial cell migration" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-140342" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LY4" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" secondary="transcription factor binding" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001200" secondary="positive regulation of dendritic cell differentiation" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019958" secondary="C-X-C chemokine binding" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166058" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5602498" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043277" secondary="apoptotic cell clearance" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033151" secondary="V(D)J recombination" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051384" secondary="response to glucocorticoid" version="SP_228"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001300821.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OEM" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CIJ" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032072" secondary="regulation of restriction endodeoxyribonuclease activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" secondary="early endosome" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006310" secondary="DNA recombination" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032732" secondary="positive regulation of interleukin-1 production" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034137" secondary="positive regulation of toll-like receptor 2 signaling pathway" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005178" secondary="integrin binding" version="SP_228"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6IBE1" version="SP_81" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030324" secondary="lung development" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_228"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002119.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017055" secondary="negative regulation of RNA polymerase II transcription preinitiation complex assembly" version="SP_228"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OEO" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006914" secondary="autophagy" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045639" secondary="positive regulation of myeloid cell differentiation" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005793" secondary="endoplasmic reticulum-Golgi intermediate compartment" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" secondary="positive regulation of interleukin-8 production" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034165" secondary="positive regulation of toll-like receptor 9 signaling pathway" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016458" secondary="gene silencing" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016829" secondary="lyase activity" version="SP_228"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009071" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002270" secondary="plasmacytoid dendritic cell activation" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5603041" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070182" secondary="DNA polymerase binding" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000399494" version="SP_228" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006284" secondary="base-excision repair" version="SP_228"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14321" version="SP_92" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032728" secondary="positive regulation of interferon-beta production" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042104" secondary="positive regulation of activated T cell proliferation" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051106" secondary="positive regulation of DNA ligation" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905564" secondary="positive regulation of vascular endothelial cell proliferation" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000339872" version="SP_228" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" secondary="DNA-binding transcription factor binding" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043280" secondary="positive regulation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_228"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A5D8W9" version="SP_92" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045819" secondary="positive regulation of glycogen catabolic process" version="SP_228"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P09429" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035868" secondary="alphav-beta3 integrin-HMGB1 complex" version="SP_228"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-24195N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" secondary="activation of innate immune response" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031175" secondary="neuron projection development" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001530" secondary="lipopolysaccharide binding" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090303" secondary="positive regulation of wound healing" version="SP_228"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5686938" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006303" secondary="double-strand break repair via nonhomologous end joining" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000819" secondary="regulation of nucleotide-excision repair" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000384678" version="SP_228" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CIM" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034145" secondary="positive regulation of toll-like receptor 4 signaling pathway" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043537" secondary="negative regulation of blood vessel endothelial cell migration" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000343" secondary="positive regulation of chemokine (C-X-C motif) ligand 2 production" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032727" secondary="positive regulation of interferon-alpha production" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000405805" version="SP_228" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097100" secondary="supercoiled DNA binding" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043005" secondary="neuron projection" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042056" secondary="chemoattractant activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002643" secondary="regulation of tolerance induction" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" secondary="cytokine activity" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050786" secondary="RAGE receptor binding" version="SP_228"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000341423" version="SP_228" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032392" secondary="DNA geometric change" version="SP_228"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017053" secondary="transcription repressor complex" version="SP_228"/>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE</sequence>
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                <names>
                    <shortLabel>ch60_human</shortLabel>
                    <fullName>60 kDa heat shock protein, mitochondrial</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">HSP60</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Heat shock protein 60</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">60 kDa chaperonin</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Chaperonin 60</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Mitochondrial matrix protein P1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">P60 lymphocyte protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HuCHA60</alias>
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                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B7Z712" version="SP_181" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_247"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_247"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001844" version="SP_247"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_247"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000428204" version="SP_247" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000402478" version="SP_247" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_247"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000418022" version="SP_247" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043627" secondary="response to estrogen" version="SP_247"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000503139" version="SP_247" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4PJ1" version="SP_247"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903427" secondary="negative regulation of reactive oxygen species biosynthetic process" version="SP_247"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF</sequence>
            </interactor>
            <interactor id="3603955">
                <names>
                    <shortLabel>tlr4_human</shortLabel>
                    <fullName>Toll-like receptor 4</fullName>
                    <alias typeAc="MI:0301" type="gene name">TLR4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">hToll</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O00206" version="SP_70" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" secondary="cellular response to mechanical stimulus" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" secondary="positive regulation of tumor necrosis factor production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UL8" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" secondary="positive regulation of interleukin-8 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002537" secondary="nitric oxide production involved in inflammatory response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043032" secondary="positive regulation of macrophage activation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010008" secondary="endosome membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z62" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032700" secondary="negative regulation of interleukin-17 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070430" secondary="positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032675" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030890" secondary="positive regulation of B cell proliferation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043406" secondary="positive regulation of MAP kinase activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060907" secondary="positive regulation of macrophage cytokine production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001875" secondary="lipopolysaccharide immune receptor activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032689" secondary="negative regulation of interferon-gamma production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" secondary="immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032707" secondary="negative regulation of interleukin-23 production" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166058" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120163" secondary="negative regulation of cold-induced thermogenesis" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003257.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042742" secondary="defense response to bacterium" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UM57" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5VZI9" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050135" secondary="NAD(P)+ nucleosidase activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" secondary="protein heterodimerization activity" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NAM" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-937041" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ULA" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A9XLQ0" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061809" secondary="NAD+ nucleotidase, cyclic ADP-ribose generating" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000157" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" secondary="early endosome" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002218" secondary="activation of innate immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014002" secondary="astrocyte development" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4G8A" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FXI" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-975163" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D1CS53" version="SP_133" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042116" secondary="macrophage activation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002322" secondary="B cell proliferation involved in immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032727" secondary="positive regulation of interferon-alpha production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001726" secondary="ruffle" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032715" secondary="negative regulation of interleukin-6 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903223" secondary="positive regulation of oxidative stress-induced neuron death" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903428" secondary="positive regulation of reactive oxygen species biosynthetic process" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z65" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K1Y8" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166016" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032728" secondary="positive regulation of interferon-beta production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045671" secondary="negative regulation of osteoclast differentiation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" secondary="amyloid-beta binding" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045429" secondary="positive regulation of nitric oxide biosynthetic process" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032733" secondary="positive regulation of interleukin-10 production" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_612564.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050729" secondary="positive regulation of inflammatory response" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A9XLP9" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5602498" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904466" secondary="positive regulation of matrix metallopeptidase secretion" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001530" secondary="lipopolysaccharide binding" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903974" secondary="positive regulation of cellular response to macrophage colony-stimulating factor stimulus" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5686938" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002224" secondary="toll-like receptor signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900227" secondary="positive regulation of NLRP3 inflammasome complex assembly" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900017" secondary="positive regulation of cytokine production involved in inflammatory response" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1236974" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002755" secondary="MyD88-dependent toll-like receptor signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071223" secondary="cellular response to lipoteichoic acid" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000343" secondary="positive regulation of chemokine (C-X-C motif) ligand 2 production" version="SP_218"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="O00206" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003591" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2562578" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031226" secondary="intrinsic component of plasma membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070434" secondary="positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140052" secondary="cellular response to oxidised low-density lipoprotein particle stimulus" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UL7" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007252" secondary="I-kappaB phosphorylation" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001611" version="SP_218"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-528701" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-140534" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071346" secondary="cellular response to interferon-gamma" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032497" secondary="detection of lipopolysaccharide" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" secondary="external side of plasma membrane" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z63" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A9XLQ1" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070373" secondary="negative regulation of ERK1 and ERK2 cascade" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" secondary="response to lipopolysaccharide" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UK78" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5VZI8" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-937072" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3UL9" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051770" secondary="positive regulation of nitric-oxide synthase biosynthetic process" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035897" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-936964" version="SP_218"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017241" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035666" secondary="TRIF-dependent toll-like receptor signaling pathway" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E194" version="SP_85" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002730" secondary="regulation of dendritic cell cytokine production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032735" secondary="positive regulation of interleukin-12 production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046696" secondary="lipopolysaccharide receptor complex" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006909" secondary="phagocytosis" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NAO" version="SP_218"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2Z66" version="SP_218"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_612567.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" secondary="positive regulation of chemokine production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060729" secondary="intestinal epithelial structure maintenance" version="SP_218"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-34769N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001891" secondary="phagocytic cup" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-166166" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9707616" version="SP_218"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5603041" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042088" secondary="T-helper 1 type immune response" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_218"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D1CS52" version="SP_134" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000483" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045348" secondary="positive regulation of MHC class II biosynthetic process" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000136869" version="SP_218" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_218"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000363089" version="SP_218" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000355622" version="SP_218" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031663" secondary="lipopolysaccharide-mediated signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010572" secondary="positive regulation of platelet activation" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034142" secondary="toll-like receptor 4 signaling pathway" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016046" secondary="detection of fungus" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032720" secondary="negative regulation of tumor necrosis factor production" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_218"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032732" secondary="positive regulation of interleukin-1 production" version="SP_218"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-27403-1" id="3603956">
                <names>
                    <shortLabel>tlr2-hmgb1-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056325" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-27403-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3603949</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3603957">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056340" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603950</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603958">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056339" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603951</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603959">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056338" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603952</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603960">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056337" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603953</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603961">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056336" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603954</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">fig. 2f</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-27403-3" id="3603962">
                <names>
                    <shortLabel>tlr2-hmgb1-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056341" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-27403-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3603949</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3603963">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056347" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603950</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603964">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056346" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603955</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603965">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056344" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603953</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3603966">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-22056343" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3603954</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">fig. 2g</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
