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    <entry>
        <source releaseDate="2018-08-08+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3465293">
                <names>
                    <shortLabel>ho-2018-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="29720648" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-20627819" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26727" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="83333">
                        <names>
                            <shortLabel>ecoli</shortLabel>
                            <fullName>Escherichia coli (strain K12)</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ho H., Miu A., Alexander MK., Garcia NK., Oh A., Zilberleyb I., Reichelt M., Austin CD., Tam C., Shriver S., Hu H., Labadie SS., Liang J., Wang L., Wang J., Lu Y., Purkey HE., Quinn J., Franke Y., Clark K., Beresini MH., Tan MW., Sellers BD., Maurer T., Koehler MFT., Wecksler AT., Kiefer JR., Verma V., Xu Y., Nishiyama M., Payandeh J., Koth CM.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">payandeh.jian@gene.com</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2018</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3465294">
                <names>
                    <shortLabel>msba_eco57</shortLabel>
                    <fullName>ATP-dependent lipid A-core flippase</fullName>
                    <alias typeAc="MI:0301" type="gene name">msbA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Lipid A export ATP-binding/permease protein MsbA</alias>
                    <alias typeAc="MI:0305" type="locus name">ECs0997</alias>
                    <alias typeAc="MI:0305" type="locus name">Z1260</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P60753" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011527"/>
                    <secondaryRef db="ensemblbacteria" id="AAG55399" version="SP_120" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003593"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011917"/>
                    <secondaryRef db="ensemblbacteria" id="BAB34420" version="SP_120" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_120"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039421"/>
                    <secondaryRef db="ensemblbacteria" id="Z1260" version="SP_120" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_120"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_120"/>
                    <secondaryRef db="ensemblbacteria" id="BAB34420" version="SP_120" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036640"/>
                    <secondaryRef db="ensemblbacteria" id="ECs_0997" version="SP_120" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_120"/>
                    <secondaryRef db="ensemblbacteria" id="AAG55399" version="SP_120" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034040" secondary="ATPase-coupled lipid transmembrane transporter activity" version="SP_120"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_309024.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P27299" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000551270.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003439"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017871"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-20627825" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="83334">
                    <names>
                        <shortLabel>eco57</shortLabel>
                        <fullName>Escherichia coli O157:H7</fullName>
                    </names>
                </organism>
                <sequence>MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-26727-1" id="3465295">
                <names>
                    <shortLabel>msba-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="6BPP" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-20627845" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="6BPL" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26727-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3465293</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3465296">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-20627846" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3465294</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="83333">
                                <names>
                                    <shortLabel>ecoli</shortLabel>
                                    <fullName>Escherichia coli (strain K12)</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                        <attributeList>
                            <attribute name="comment" nameAc="MI:0612">Stoichiometry: 2.0</attribute>
                        </attributeList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 2, Extended Data Table 1</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
