UniProt UniProt http://www.uniprot.org hartmann-2018-1 human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Hartmann S., Zheng F., Kyncl MC., Karch S., Voelkl K., Zott B., D'Avanzo C., Lomoio S., Tesco G., Kim DY., Alzheimer C., Huth T. Alzheimers - Interactions investigated in the context of Alzheimers disease tobias.huth@fau.de, christian.alzheimer@fau.de < The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Only protein-protein interactions imex curation imex curation hartmann-2018-3 human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. frap fluorescence recovery after photobleaching frap tag fluorescence tag visualisation by fluorescence tag fluorescence Hartmann S., Zheng F., Kyncl MC., Karch S., Voelkl K., Zott B., D'Avanzo C., Lomoio S., Tesco G., Kim DY., Alzheimer C., Huth T. Alzheimers - Interactions investigated in the context of Alzheimers disease tobias.huth@fau.de, christian.alzheimer@fau.de < The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Only protein-protein interactions imex curation imex curation kcnc4_human Potassium voltage-gated channel subfamily C member 4 C1orf30 KCNC4 KSHIIIC Voltage-gated potassium channel subunit Kv3.4 protein protein human Homo sapiens Human MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADSKQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACADGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH bace1_human Beta-secretase 1 BACE KIAA1149 Beta-site amyloid precursor protein cleaving enzyme 1 Membrane-associated aspartic protease 2 Memapsin-2 Aspartyl protease 2 BACE1 protein protein human Homo sapiens Human MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRQQHDDFADDISLLK 377CE4C824ACEF05 bace1-kcnc4-1 3494482 N/A 3494484 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed engineered engineered N/A 3494485 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed engineered engineered physical association physical association false false false Fig. 8A bace1-kcnc4-2 3494482 N/A 3494484 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed engineered engineered N/A 3494485 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed engineered engineered physical association physical association false false false Fig. 8B kcnc4-bace1-1 3494483 N/A 3494484 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed engineered engineered N/A 3494485 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed engineered engineered region egfp tag enhanced green fluorescent protein tag enhanced green fluorescent protein EGFP enhanced green fluorescent protein EGFP egfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false physical association physical association false false false Fig. 8C