DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ kouznetsova-2016-1 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Kouznetsova E., Kanno T., Karlberg T., Thorsell AG., Wisniewska M., Kursula P., Sjögren C., Schüler H. DIP original experiment: DIP-268508X Structure (London, England : 1993) 2016 IMEx Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis. Kouznetsova E., Kanno T., Karlberg T., Thorsell AG., Wisniewska M., Kursula P., Sjögren C., Schüler H. Only protein-protein interactions imex curation kouznetsova-2016-2 ecolx Escherichia coli saxs x ray scattering saxs predetermined predetermined participant predetermined Kouznetsova E., Kanno T., Karlberg T., Thorsell AG., Wisniewska M., Kursula P., Sjögren C., Schüler H. DIP original experiment: DIP-268509X Structure (London, England : 1993) 2016 IMEx Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis. Kouznetsova E., Kanno T., Karlberg T., Thorsell AG., Wisniewska M., Kursula P., Sjögren C., Schüler H. Only protein-protein interactions imex curation kouznetsova-2016-3 in vitro In vitro acetylase assay acetylase assay weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Kouznetsova E., Kanno T., Karlberg T., Thorsell AG., Wisniewska M., Kursula P., Sjögren C., Schüler H. DIP original experiment: DIP-268510X Structure (London, England : 1993) 2016 IMEx Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis. Kouznetsova E., Kanno T., Karlberg T., Thorsell AG., Wisniewska M., Kursula P., Sjögren C., Schüler H. Only protein-protein interactions imex curation q5fwf5-1 N-acetyltransferase ESCO1 ESCO1 EFO1 KIAA1911 CTF7 homolog 1 Establishment factor-like protein 1 Establishment of cohesion 1 homolog 1 protein protein human Homo sapiens Human MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST esco1-1 3291377 N/A 3291380 unspecified role unspecified role unspecified role unspecified role Region 654-836 Region 654-836 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false esco1-2 3291378 N/A 3291380 unspecified role unspecified role unspecified role unspecified role Region 654-836 Region 654-836 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false esco1-3 3291379 N/A 3291380 putative self putative self unspecified role unspecified role Region 654-836 Region 654-836 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false Q5FWF5-1:p.Gly768Asp G768D mutation disrupting rate mutation disrupting interaction rate mutation disrupting rate substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false Q5FWF5-1:p.Arg780Ala R780A mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false Q5FWF5-1:p.Glu789Ala E789A mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false Q5FWF5-1:p.Lys803Ala K803A mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false ac-K ac-K naclys N-acetylated L-lysine NAcLys modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Resulting PTM ecolx Escherichia coli acetylation acetylation reaction acetylation false false false