DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ zhao-2016-6 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268612X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268624X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-8 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268616X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-9 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268619X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-10 in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268629X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-11 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268631X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-12 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268628X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-13 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268613X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-14 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268620X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-15 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268625X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-16 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268617X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-17 in vitro In vitro fps fluorescence polarization spectroscopy Fluorescence anisotropy FPS FPS Fluorescence anisotropy fps predetermined predetermined participant predetermined Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268630X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-18 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268622X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-19 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268626X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-20 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268621X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-21 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268614X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-22 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268623X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-23 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268618X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-24 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268627X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation zhao-2016-25 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. DIP original experiment: DIP-268615X Nature 2016 IMEx SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Zhao DY., Gish G., Braunschweig U., Li Y., Ni Z., Schmitges FW., Zhong G., Liu K., Li W., Moffat J., Vedadi M., Min J., Pawson TJ., Blencowe BJ., Greenblatt JF. Only protein-protein interactions imex curation xrn2_human 5'-3' exoribonuclease 2 XRN2 DHM1-like protein protein protein human Homo sapiens Human MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFSIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCGLCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFTFDVERSIDDWVFMCFFVGNDFLPHLPSLEIRENAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPHALGSRNSPGSQVASNPRQAAYEMRMQNNSSPSISPNTSFTSDGSPSPLGGIKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSDFEKGTKPFKPLEQLMGVFPAASGNFLPPSWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEETRRNSLGGDVLFVGKHHPLHDFILELYQTGSTEPVEVPPELCHGIQGKFSLDEEAILPDQIVCSPVPMLRDLTQNTVVSINFKDPQFAEDYIFKAVMLPGARKPAAVLKPSDWEKSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVMPRGSGTGIYSNAAPPPVTYQGNLYRPLLRGQAQIPKLMSNMRPQDSWRGPPPLFQQQRFDRGVGAEPLLPWNRMLQTQNAAFQPNQYQMLAGPGGYPPRRDDRGGRQGYPREGRKYPLPPPSGRYNWN setx_human Probable helicase senataxin SETX ALS4 KIAA0625 SCAR1 SEN1 homolog Amyotrophic lateral sclerosis 4 protein Senataxin protein protein human Homo sapiens Human MSTCCWCTPGGASTIDFLKRYASNTPSGEFQTADEDLCYCLECVAEYHKARDELPFLHEVLWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKYPYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGKVDRDDYYDLQEVLLCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEREADDDSVDPFWPALHCFMVILDRLGSKVWGQLMDPIVAFQTIINNASYNREIRHIRNSSVRTKLEPESYLDDMVTCSQIVYNYNPEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMDLKDLGVAYIAQVVNHLYSEVKEVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLAYVQLIRSLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQSCLKQIIRNIKFKAPPCNTFVDLTSACKISPASYNKEESEQMGKTSRKDMHCLEASSPTFSKEPMKVQDSVLIKADNTIEGDNNEQNYIKDVKLEDHLLAGSCLKQSSKNIFTERAEDQIKISTRKQKSVKEISSYTPKDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKTKVQKDEICAKLSHVIKKQHRKSTLVDNTINLDENLTVSNIESFYSRKDTGVQKGDGFIHNLSLDPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCKIQEFHVDGKELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLTREQAPDISPKSDTLTDSQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQNNVGDTSRGQVIIISDSDDDDDERILSLEKLTKQDKICLEREHPEQHVSTVNSKEEKNPVKEEKTETLFQFEESDSQCFEFESSSEVFSVWQDHPDDNNSVQDGEKKCLAPIANTTNGQGCTDYVSEVVKKGAEGIEEHTRPRSISVEEFCEIEVKKPKRKRSEKPMAEDPVRPSSSVRNEGQSDTNKRDLVGNDFKSIDRRTSTPNSRIQRATTVSQKKSSKLCTCTEPIRKVPVSKTPKKTHSDAKKGQNRSSNYLSCRTTPAIVPPKKFRQCPEPTSTAEKLGLKKGPRKAYELSQRSLDYVAQLRDHGKTVGVVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRRRLSDCESTDVKRAGSHTAQNSDIFVPESDRSDYNCTGGTEVLANSNRKQLIKCMPSEPETIKAKHGSPATDDACPLNQCDSVVLNGTVPTNEVIVSTSEDPLGGGDPTARHIEMAALKEGEPDSSSDAEEDNLFLTQNDPEDMDLCSQMENDNYKLIELIHGKDTVEVEEDSVSRPQLESLSGTKCKYKDCLETTKNQGEYCPKHSEVKAADEDVFRKPGLPPPASKPLRPTTKIFSSKSTSRIAGLSKSLETSSALSPSLKNKSKGIQSILKVPQPVPLIAQKPVGEMKNSCNVLHPQSPNNSNRQGCKVPFGESKYFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFGQCGPPASLCQSISRPVPVRFHNYGDYFNVFFPLMVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEECELAKQLYPKENDLVFLAPERINEEKKDTERNDIQDLHEYHSGYVHKFRRTSVMRNGKTECYLSIQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNHRMKKELPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL anm5_human Protein arginine N-methyltransferase 5 PRMT5 IBP72 JBP1 HRMT1L5 Shk1 kinase-binding protein 1 homolog Jak-binding protein 1 72 kDa ICln-binding protein SKB1 Histone-arginine N-methyltransferase PRMT5 protein protein human Homo sapiens Human MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL smn_human Survival motor neuron protein SMN1 SMN SMNT SMN2 SMNC Component of gems 1 Gemin-1 protein protein human Homo sapiens Human MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN rpb1_human DNA-directed RNA polymerase II subunit RPB1 POLR2A DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit POLR2 RNA-directed RNA polymerase II subunit RPB1 protein protein human Homo sapiens Human MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN tdrd3_human Tudor domain-containing protein 3 TDRD3 protein protein human Homo sapiens Human MLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGARSNLNMNAAGNRNREVLQKEKSTKSEGKHEGVYRELVDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSNKQKPVMGPPLRGRGKGRGRIRSEDEEDLGNARPSAPSTLFDFLESKMGTLNVEEPKSQPQQLHQGQYRSSNTEQNGVKDNNHLRHPPRNDTRQPRNEKPPRFQRDSQNSKSVLEGSGLPRNRGSERPSTSSVSEVWAEDRIKCDRPYSRYDRTKDTSYPLGSQHSDGAFKKRDNSMQSRSGKGPSFAEAKENPLPQGSVDYNNQKRGKRESQTSIPDYFYDRKSQTINNEAFSGIKIEKHFNVNTDYQNPVRSNSFIGVPNGEVEMPLKGRRIGPIKPAGPVTAVPCDDKIFYNSGPKRRSGPIKPEKILESSIPMEYAKMWKPGDECFALYWEDNKFYRAEVEALHSSGMTAVVKFIDYGNYEEVLLSNIKPIQTEAWEEEGTYDQTLEFRRGGDGQPRRSTRPTQQFYQPPRARN polr2a-prmt5-1 3287192 N/A 3287212 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287214 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false smn1-polr2a-1 3287193 N/A 3287215 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3287216 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false polr2a-smn1-1 3287194 N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false polr2a-setx-1 3287195 N/A 3287216 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false P24928:p.Arg1810Ala R1810A mutation mutation certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false polr2a-smn1-2 3287196 N/A 3287216 unspecified role unspecified role unspecified role unspecified role Region 1804-1816 Region 1804-1816 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false R1810me2 R1810me2 nnme2arg dimethylated L-arginine Dimethyl NNMe2Arg dimethylr certain certain sequence position certain certain certain sequence position certain false FITC-label FITC-label fitc labelled fluorescein isothiocyanate label fluorescein isothiocyanate labbeled FITC labelled FITC labelled fluorescein isothiocyanate labbeled fitc labelled n-term range n-terminal range n-term range n-term range n-terminal range n-term range false in vitro In vitro N/A 3287215 unspecified role unspecified role unspecified role unspecified role Region 80-170 Region 80-170 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false polr2a-smn1-3 3287197 N/A 3287216 unspecified role unspecified role unspecified role unspecified role Region 1801-1815 Region 1801-1815 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false R1810me2 R1810me2 nnme2arg dimethylated L-arginine Dimethyl NNMe2Arg dimethylr certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3287215 unspecified role unspecified role unspecified role unspecified role Region 80-170 Region 80-170 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false prmt5-polr2a-1 3287198 N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287214 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false smn1-polr2a-2 3287199 N/A 3287212 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287214 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3287216 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false smn1-setx-1 3287200 N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false polr2a-prmt5-2 3287201 N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287214 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false polr2a-setx-2 3287202 N/A 3287216 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3287217 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false polr2a-smn1-4 3287203 N/A 3287216 unspecified role unspecified role unspecified role unspecified role Region 1597-1610 Region 1597-1610 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false R1603me2 R1603me2 nnme2arg dimethylated L-arginine Dimethyl NNMe2Arg dimethylr certain certain sequence position certain certain certain sequence position certain false FITC-label FITC-label fitc labelled fluorescein isothiocyanate label fluorescein isothiocyanate labbeled FITC labelled FITC labelled fluorescein isothiocyanate labbeled fitc labelled n-term range n-terminal range n-term range n-term range n-terminal range n-term range false in vitro In vitro N/A 3287215 unspecified role unspecified role unspecified role unspecified role Region 80-170 Region 80-170 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false polr2a-setx-3 3287204 N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false polr2a-setx-4 3287205 N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false setx-smn1-1 3287206 N/A 3287213 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false polr2a-prmt5-3 3287207 N/A 3287214 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false tdrd3-polr2a-1 3287208 N/A 3287217 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human N/A 3287216 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false polr2a-smn1-5 3287209 N/A 3287216 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false P24928:p.Arg1810Ala R1810A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3287217 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false polr2a-prmt5-4 3287210 N/A 3287213 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287214 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false polr2a-prmt5-5 3287211 N/A 3287214 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287215 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3287216 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false