DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ wertz-2015-1 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267908X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-2 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267884X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-3 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267889X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-4 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267900X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-5 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267898X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-6 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267890X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-7 in vitro In vitro anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267907X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-8 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267899X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-9 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267891X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-10 mouse Mus musculus Mouse coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267902X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-11 in vitro In vitro bio-layer interferometry bio-layer interferometry bli bli predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267909X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-12 human Homo sapiens Human coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267901X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-13 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267885X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-14 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267892X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-15 in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267894X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-16 in vitro In vitro deubiquitinase assay deubiquitinase assay deubiquitinase assay western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267893X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-17 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267895X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-18 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267903X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-19 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267886X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-20 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267896X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-21 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267905X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-22 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267906X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-23 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267904X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-24 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267887X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-25 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267897X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation wertz-2015-26 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. DIP original experiment: DIP-267888X Nature 2015 IMEx Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Wertz IE., Newton K., Seshasayee D., Kusam S., Lam C., Zhang J., Popovych N., Helgason E., Schoeffler A., Jeet S., Ramamoorthi N., Kategaya L., Newman RJ., Horikawa K., Dugger D., Sandoval W., Mukund S., Zindal A., Martin F., Quan C., Tom J., Fairbrother WJ., Townsend M., Warming S., DeVoss J., Liu J., Dueber E., Caplazi P., Lee WP., Goodnow CC., Balazs M., Yu K., Kolumam G., Dixit VM. Only protein-protein interactions imex curation ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG tnap3_human Tumor necrosis factor alpha-induced protein 3 Putative DNA-binding protein A20 Zinc finger protein A20 TNFAIP3 OTUD7C OTU domain-containing protein 7C protein protein human Homo sapiens Human MAEQVLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIHHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRNIQATLESQKKLNWCREVRKLVALKTNGDGNCLMHATSQYMWGVQDTDLVLRKALFSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLIKMASTDTPMARSGLQYNSLEEIHIFVLCNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSHHFVPLVTLKDSGPEIRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLMVIEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSEQGRREGHAQNPMEPSVPQLSLMDVKCETPNCPFFMSVNTQPLCHECSERRQKNQNKLPKLNSKPGPEGLPGMALGASRGEAYEPLAWNPEESTGGPHSAPPTAPSPFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHNARQLHASHAPDHTRHLDPGKCQACLQDVTRTFNGICSTCFKRTTAEASSSLSTSLPPSCHQRSKSDPSRLVRSPSPHSCHRAGNDAPAGCLSQAARTPGDRTGTSKCRKAGCVYFGTPENKGFCTLCFIEYRENKHFAAASGKVSPTASRFQNTIPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEAKRTEEQLRSSQRRDVPRTTQSTSRPKCARASCKNILACRSEELCMECQHPNQRMGPGAHRGEPAPEDPPKQRCRAPACDHFGNAKCNGYCNECFQFKQMYG tnap3_mouse Tumor necrosis factor alpha-induced protein 3 Putative DNA-binding protein A20 Zinc finger protein A20 Tnfaip3 Tnfip3 protein protein mouse Mus musculus Mouse MAEQLLPQALYLSNMRKAVKIRERTPEDIFKPTNGIIYHFKTMHRYTLEMFRTCQFCPQFREIIHKALIDRSVQASLESQKKLNWCREVRKLVALKTNGDGNCLMHAACQYMWGVQDTDLVLRKALCSTLKETDTRNFKFRWQLESLKSQEFVETGLCYDTRNWNDEWDNLVKMASADTPAARSGLQYNSLEEIHIFVLSNILRRPIIVISDKMLRSLESGSNFAPLKVGGIYLPLHWPAQECYRYPIVLGYDSQHFVPLVTLKDSGPELRAVPLVNRDRGRFEDLKVHFLTDPENEMKEKLLKEYLIVMEIPVQGWDHGTTHLINAAKLDEANLPKEINLVDDYFELVQHEYKKWQENSDQARRAAHAQNPLEPSTPQLSLMDIKCETPNCPFFMSVNTQPLCHECSERRQKNQSKLPKLNSKLGPEGLPGVGLGSSNWSPEETAGGPHSAPPTAPSLFLFSETTAMKCRSPGCPFTLNVQHNGFCERCHARQINASHTADPGKCQACLQDVTRTFNGICSTCFKRTTAEPSSSLTSSIPASCHQRSKSDPSQLIQSLTPHSCHRTGNVSPSGCLSQAARTPGDRAGTSKCRKAGCMYFGTPENKGFCTLCFIEYRENKQSVTASEKAGSPAPRFQNNVPCLGRECGTLGSTMFEGYCQKCFIEAQNQRFHEARRTEEQLRSSQHRDMPRTTQVASRLKCARASCKNILACRSEELCMECQHLSQRVGSVAHRGEPTPEEPPKQRCRAPACDHFGNAKCNGYCNECYQFKQMYG ikkb_mouse Inhibitor of nuclear factor kappa-B kinase subunit beta I-kappa-B kinase 2 Nuclear factor NF-kappa-B inhibitor kinase beta Ikbkb Ikkb Serine/threonine protein kinase IKBKB protein protein mouse Mus musculus Mouse MSWSPSLPTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIKQCRQELSPKNRNRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGAVKFSSSLPFPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNMVTGTVHTYPVTEDESLQSLKTRIQENTGILETDQELLQKAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLLDNSKINYETQITPRPPPESVSCILQEPKRNLSFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMSLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYKEQTEFGITSDKLLLAWREMEQAVEQCGRENDVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRKLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDERTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNVSRLSHPGQLMSQPSSACDSLPESDKKSEELVAEAHALCSRLESALQDTVKEQDRSFTTLDWSWLQMEDEERCSLEQACD nemo_mouse NF-kappa-B essential modulator NF-kappa-B essential modifier Inhibitor of nuclear factor kappa-B kinase subunit gamma IkB kinase-associated protein 1 Ikbkg Nemo protein protein mouse Mus musculus Mouse MNKHPWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKDRQALEGRIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKEYLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETPQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE ikka_mouse Inhibitor of nuclear factor kappa-B kinase subunit alpha I-kappa-B kinase 1 Conserved helix-loop-helix ubiquitous kinase Nuclear factor NF-kappa-B inhibitor kinase alpha Chuk Ikka protein protein mouse Mus musculus Mouse MERPPGLRPGAGGPWEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLELSSKNRERWCHEIQIMKKLDHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLMLNWDPQQRGGPIDLTLKQPRCFALMDHILNLKIVHILNMTSAKIISFLLPCDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFRKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYSEVGVIGYLEDQIMSLHTEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPPDHLYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGTVTPPVSAWLPPTLADREHPLTCVVTPQDGETLAQMIEENLNCLGHLSTIIREANEDQSSSLMSLDWSWLAE cyld_mouse Ubiquitin carboxyl-terminal hydrolase CYLD Cyld Cyld1 Kiaa0849 Ubiquitin-specific-processing protease CYLD Deubiquitinating enzyme CYLD Ubiquitin thioesterase CYLD protein protein mouse Mus musculus Mouse MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRVPSTKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERLSLFRNRLRLSKGLQVDVGSPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDNGLESDFAGPGDTMQVEPPPLEINSRVSLKVGESTESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFASVESTILLHINDIIPDSVTQERRPPKLAFMSRGVGDKGSSSHNKPKVTGSTSDPGSRNRSELFYTLNGSSVDSQQSKSKNPWYIDEVAEDPAKSLTEMSSDFGHSSPPPQPPSMNSLSSENRFHSLPFSLTKMPNTNGSMAHSPLSLSVQSVMGELNSTPVQESPPLPISSGNAHGLEVGSLAEVKENPPFYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVLLRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK rnf31_mouse E3 ubiquitin-protein ligase RNF31 HOIL-1-interacting protein Rnf31 Paul Putative Ariadne-like ubiquitin ligase RING finger protein 31 RING-type E3 ubiquitin transferase RNF31 protein protein mouse Mus musculus Mouse MPGDEERGFLAAREELASALRWDSAQVFPLEQLMPLLATSLPPAARYLQLDAGRLVRCNAHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRSVKFNNPVFRSTVDAVQGGRDVLRLYGYTEERPDGLSFPEGQEEPDEYQVAVVTLEVLLLRTELSLLLQNTHPRQNALDQLLRESVEDGMLQLSEFHPLLREIVPGPRPSAQGSTPGPCFLCGSAPGTLHCPACNQVSCPACDILFHGHPSRAHHLRQALPGSHQTASLSSSLPASSQPRPPSSSLALGDSSLSSPDPANACLPWHCLTCATLNEPWAVFCAVCSQPKGCKVPGIEGSHGTGGLEPEPARDQWACQSCTFENEAAAVLCAICERPRLAQPPSLVVDSHDAGVCQQSLKQEDPLLTAAQPQVWYCDHCTFCNSGPVWVCAMCNRTRDPIPTQPALQSYPSSLEKGRPKPGSSQHLGSSLPASCGDPEKQRQDKMRKEGLQLVSMIQEGETAGASPEEVFSALQYSGTEVPLQWLRSELSYVLEMVAELAGQQDPELGAFSCQEARKAWLDRHGNLDEAVEECVRARRRKVHELQSLGFGPKEGSLQALFQHGGDVARALTELQRQRLEPFHQRLWDRDPEPTPCWDGLDRQSLVRRLLAVYTLPSWGRAELALALLQETPRNYELLDVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRVMEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATIRYLHLAPQPADGEDLPAYQARLLQKLREEVPLGQSIARRRK traf5_mouse TNF receptor-associated factor 5 Traf5 protein protein mouse Mus musculus Mouse MAHSEEQAAVPCAFIRQNSGNSISLDFEPDTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHEENSCPAYPVSCPNRCVQTIPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDLTDLEDL traf2_mouse TNF receptor-associated factor 2 Traf2 E3 ubiquitin-protein ligase TRAF2 RING-type E3 ubiquitin transferase TRAF2 protein protein mouse Mus musculus Mouse MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL tradd_mouse Tumor necrosis factor receptor type 1-associated DEATH domain protein Tradd TNFRSF1A-associated via death domain protein protein mouse Mus musculus Mouse MAAGQNGHEEWVGSAYLFLESAVDKVILSEAYTDPKKKVAIYKALQTALSESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQEALRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDELCKLTCDCTGQGGAIQVASAGSKFPVSSPTEEKPLPAACQTFLFHGQLVVNRPLTLQDQQTFARSVGLKWRRVGRSLQRNCRALRDPALDSLAYEYERDGLYEQAFQLLRRFMQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPDGGLA ripk1_mouse Receptor-interacting serine/threonine-protein kinase 1 Cell death protein RIP Receptor-interacting protein 1 Ripk1 Rinp Rip protein protein mouse Mus musculus Mouse MQPDMSLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVLQRMFSLQHDCVPLPPSRSNSEQPGSLHSSQGLQMGPVEESWFSSSPEYPQDENDRSVQAKLQEEASYHAFGIFAEKQTKPQPRQNEAYNREEERKRRVSHDPFAQQRARENIKSAGARGHSDPSTTSRGIAVQQLSWPATQTVWNNGLYNQHGFGTTGTGVWYPPNLSQMYSTYKTPVPETNIPGSTPTMPYFSGPVADDLIKYTIFNSSGIQIGNHNYMDVGLNSQPPNNTCKEESTSRHQAIFDNTTSLTDEHLNPIRENLGRQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRIDLLNHLIRASQS tnr1a_mouse Tumor necrosis factor receptor superfamily member 1A p60 Tumor necrosis factor receptor 1 Tumor necrosis factor receptor type I p55 Tnfrsf1a Tnfr1 Tnfr-1 protein protein mouse Mus musculus Mouse MGLPTVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDSLCPQGKYVHSKNNSICCTKCHKGTYLVSDCPSPGRDTVCRECEKGTFTASQNYLRQCLSCKTCRKEMSQVEISPCQADKDTVCGCKENQFQRYLSETHFQCVDCSPCFNGTVTIPCKETQNTVCNCHAGFFLRESECVPCSHCKKNEECMKLCLPPPLANVTNPQDSGTAVLLPLVILLGLCLLSFIFISLMCRYPRWRPEVYSIICRDPVPVKEEKAGKPLTPAPSPAFSPTSGFNPTLGFSTPGFSSPVSSTPISPIFGPSNWHFMPPVSEVVPTQGADPLLYESLCSVPAPTSVQKWEDSAHPQRPDNADLAILYAVVDGVPPARWKEFMRFMGLSEHEIERLEMQNGRCLREAQYSMLEAWRRRTPRHEDTLEVVGLVLSKMNLAGCLENILEALRNPAPSSTTRLPR tnfa_human Tumor necrosis factor TNF TNFA TNFSF2 TNF-alpha Tumor necrosis factor ligand superfamily member 2 Cachectin protein protein human Homo sapiens Human MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL ripk3_mouse Receptor-interacting serine/threonine-protein kinase 3 Ripk3 Rip3 RIP-like protein kinase 3 Receptor-interacting protein 3 protein protein mouse Mus musculus Mouse MSSVKLWPTGASAVPLVSREELKKLEFVGKGGFGVVFRAHHRTWNHDVAVKIVNSKKISWEVKAMVNLRNENVLLLLGVTEDLQWDFVSGQALVTRFMENGSLAGLLQPECPRPWPLLCRLLQEVVLGMCYLHSLNPPLLHRDLKPSNILLDPELHAKLADFGLSTFQGGSQSGSGSGSGSRDSGGTLAYLDPELLFDVNLKASKASDVYSFGILVWAVLAGREAELVDKTSLIRETVCDRQSRPPLTELPPGSPETPGLEKLKELMIHCWGSQSENRPSFQDCEPKTNEVYNLVKDKVDAAVSEVKHYLSQHRSSGRNLSAREPSQRGTEMDCPRETMVSKMLDRLHLEEPSGPVPGKCPERQAQDTSVGPATPARTSSDPVAGTPQIPHTLPFRGTTPGPVFTETPGPHPQRNQGDGRHGTPWYPWTPPNPMTGPPALVFNNCSEVQIGNYNSLVAPPRTTASSSAKYDQAQFGRGRGWQPFHK fadd_mouse FAS-associated death domain protein FAS-associating death domain-containing protein Mediator of receptor induced toxicity Fadd Mort1 protein protein mouse Mus musculus Mouse MDPFLVLLHSLSGSLSGNDLMELKFLCRERVSKRKLERVQSGLDLFTVLLEQNDLERGHTGLLRELLASLRRHDLLQRLDDFEAGTATAAPPGEADLQVAFDIVCDNVGRDWKRLARELKVSEAKMDGIEEKYPRSLSERVRESLKVWKNAEKKNASVAGLVKALRTCRLNLVADLVEEAQESVSKSENMSPVLRDSTVSSSETP casp8_mouse Caspase-8 Casp8 protein protein mouse Mus musculus Mouse MDFQSCLYAIAEELGSEDLAALKFLCLDYIPHKKQETIEDAQKLFLRLREKGMLEEGNLSFLKELLFHISRWDLLVNFLDCNREEMVRELRDPDNAQISPYRVMLFKLSEEVSELELRSFKFLLNNEIPKCKLEDDLSLLEIFVEMEKRTMLAENNLETLKSICDQVNKSLLGKIEDYERSSTERRMSLEGREELPPSVLDEMSLKMAELCDSPREQDSESRTSDKVYQMKNKPRGYCLIINNHDFSKAREDITQLRKMKDRKGTDCDKEALSKTFKELHFEIVSYDDCTANEIHEILEGYQSADHKNKDCFICCILSHGDKGVVYGTDGKEASIYDLTSYFTGSKCPSLSGKPKIFFIQACQGSNFQKGVPDEAGFEQQNHTLEVDSSSHKNYIPDEADFLLGMATVKNCVSYRDPVNGTWYIQSLCQSLRERCPQGDDILSILTGVNYDVSNKDDRRNKGKQMPQPTFTLRKKLFFPP ubiq_mouse Ubiquitin Rps27a Uba80 Ubcep1 Uba52 Ubcep2 Ubb Ubc protein protein mouse Mus musculus Mouse MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG ikkb_human Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB IKKB I-kappa-B kinase 2 Nuclear factor NF-kappa-B inhibitor kinase beta Serine/threonine protein kinase IKBKB protein protein human Homo sapiens Human MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS traf6_mouse TNF receptor-associated factor 6 RING-type E3 ubiquitin transferase TRAF6 Traf6 E3 ubiquitin-protein ligase TRAF6 protein protein mouse Mus musculus Mouse MSLLNCENSCGSSQSSSDCCAAMAASCSAAVKDDSVSGSASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEKEIHDQSCPLANIICEYCGTILIREQMPNHYDLDCPTAPIPCTFSVFGCHEKMQRNHLARHLQENTQLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQCNGIYIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEALIRQNHEEVMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQGTFIKDDTLLVRCEVSTRFDMGGLRKEGFQPRSTDAGV m3k7_mouse Mitogen-activated protein kinase kinase kinase 7 Map3k7 Tak1 Transforming growth factor-beta-activated kinase 1 protein protein mouse Mus musculus Mouse MSTASAASSSSSSSASEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIVATAGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPARSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS hub-tnfaip3-1 3286347 N/A 3286373 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3286374 unspecified role unspecified role unspecified role unspecified role Region 592-635 Region 592-635 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false Region 758-790 Region 758-790 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false P21580:p.[Cys624Ala;Cys627Ala] C624A/C627A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false P21580:p.[Tyr614Ala;Phe615Ala] Y614A/F615A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false P21580:p.[Phe770Ala;Gly771Ala] F770A/G771A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false tnf-chuk-1 3286348 N/A 3286375 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286376 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286377 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286378 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286379 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286380 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286381 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286382 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286383 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286385 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse association association false false false tnf-ikbkb-1 3286349 N/A 3286376 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false tnf-tnfaip3-1 3286350 N/A 3286375 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false fadd-ripk3-1 3286351 N/A 3286387 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286388 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false tnf-tradd-1 3286352 N/A 3286383 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false hub-tnfrsf1a-1 3286353 N/A 3286373 unspecified role unspecified role bait bait ecolx Escherichia coli N/A 3286385 unspecified role unspecified role prey prey ecolx Escherichia coli physical association physical association false false false fadd-casp8-15 3286354 N/A 3286389 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286388 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false mub-tnfrsf1a-1 3286355 N/A 3286390 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3286385 unspecified role unspecified role prey prey mouse Mus musculus Mouse physical association physical association false false false mub-ripk1-1 3286356 N/A 3286390 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false tnfaip3-hub-1 3286357 N/A 3286373 unspecified role unspecified role prey prey ecolx Escherichia coli N/A 3286374 unspecified role unspecified role bait bait Region 592-635 Region 592-635 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false Region 758-790 Region 758-790 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false P21580:p.[Cys624Ala;Cys627Ala] C624A/C627A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false P21580:p.[Tyr614Ala;Phe615Ala] Y614A/F615A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false P21580:p.[Phe770Ala;Gly771Ala] F770A/G771A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false hub-tnfrsf1a-2 3286358 N/A 3286373 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3286385 unspecified role unspecified role prey prey P25118:p.Lys256Arg K256R mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tnf-chuk-2 3286359 N/A 3286376 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286377 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286378 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286379 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286380 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286381 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286385 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse association association false false false mub-ripk1-2 3286360 N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286390 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false ikbkb-tnfaip3-1 3286361 N/A 3286391 enzyme enzyme unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm N/A 3286374 enzyme target enzyme target substrate substrate unspecified role unspecified role pS381 pS381 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli phosphorylation phosphorylation reaction phosphorylation false false false hub-tnfaip3-2 3286362 N/A 3286373 enzyme target enzyme target substrate substrate unspecified role unspecified role K48Ub K48Ub ubiquitinylated lysine ubiquitinylated lysine certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3286374 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli deubiquitination deubiquitination reaction deubiquitination false false false tnf-casp8-1 3286363 N/A 3286389 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false tnf-casp8-2 3286364 N/A 3286387 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286389 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse association association false false false tnf-tnfrsf1a-9 3286365 N/A 3286385 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false fadd-tnfrsf1a-1 3286366 N/A 3286388 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3286385 unspecified role unspecified role prey prey mouse Mus musculus Mouse physical association physical association false false false mub-traf6-1 3286367 N/A 3286392 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286390 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false mub-ripk1-3 3286368 N/A 3286390 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286385 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false fadd-ripk1-11 3286369 N/A 3286390 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286388 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false tnf-ripk1-1 3286370 N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false fadd-ripk1-12 3286371 N/A 3286384 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286388 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false tnf-map3k7-1 3286372 N/A 3286393 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3286386 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false