DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ okoye_okafor-2015-1 spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Okoye-Okafor UC., Bartholdy B., Cartier J., Gao EN., Pietrak B., Rendina AR., Rominger C., Quinn C., Smallwood A., Wiggall KJ., Reif AJ., Schmidt SJ., Qi H., Zhao H., Joberty G., Faelth-Savitski M., Bantscheff M., Drewes G., Duraiswami C., Brady P., Groy A., Narayanagari SR., Antony-Debre I., Mitchell K., Wang HR., Kao YR., Christopeit M., Carvajal L., Barreyro L., Paietta E., Makishima H., Will B., Concha N., Adams ND., Schwartz B., McCabe MT., Maciejewski J., Verma A., Steidl U. DIP original experiment: DIP-268147X Nature chemical biology 2015 IMEx New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Okoye-Okafor UC., Bartholdy B., Cartier J., Gao EN., Pietrak B., Rendina AR., Rominger C., Quinn C., Smallwood A., Wiggall KJ., Reif AJ., Schmidt SJ., Qi H., Zhao H., Joberty G., Faelth-Savitski M., Bantscheff M., Drewes G., Duraiswami C., Brady P., Groy A., Narayanagari SR., Antony-Debre I., Mitchell K., Wang HR., Kao YR., Christopeit M., Carvajal L., Barreyro L., Paietta E., Makishima H., Will B., Concha N., Adams ND., Schwartz B., McCabe MT., Maciejewski J., Verma A., Steidl U. Only protein-protein interactions imex curation idhc_human Isocitrate dehydrogenase [NADP] cytoplasmic Cytosolic NADP-isocitrate dehydrogenase Oxalosuccinate decarboxylase NADP(+)-specific ICDH IDP IDH1 PICD protein protein human Homo sapiens Human MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL idh1-3 3284500 N/A 3284501 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction false false false