DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ reubold-2015-1 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. DIP original experiment: DIP-267145X Nature 2015 IMEx Crystal structure of the dynamin tetramer. Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. Only protein-protein interactions imex curation reubold-2015-2 ecolx Escherichia coli tem transmission electron microscopy tem predetermined predetermined participant predetermined Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. DIP original experiment: DIP-267148X Nature 2015 IMEx Crystal structure of the dynamin tetramer. Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. Only protein-protein interactions imex curation reubold-2015-3 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. DIP original experiment: DIP-267146X Nature 2015 IMEx Crystal structure of the dynamin tetramer. Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. Only protein-protein interactions imex curation reubold-2015-4 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. DIP original experiment: DIP-267149X Nature 2015 IMEx Crystal structure of the dynamin tetramer. Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. Only protein-protein interactions imex curation reubold-2015-5 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. DIP original experiment: DIP-267147X Nature 2015 IMEx Crystal structure of the dynamin tetramer. Reubold TF., Faelber K., Plattner N., Posor Y., Ketel K., Curth U., Schlegel J., Anand R., Manstein DJ., Noé F., Haucke V., Daumke O., Eschenburg S. Only protein-protein interactions imex curation q9uq16-2 Dynamin-3 KIAA0820 Dynamin, testicular T-dynamin DNM3 protein protein human Homo sapiens Human MGNREMEELIPLVNRLQDAFSALGQSCLLELPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVTSKAEYAEFLHCKGKKFTDFDEVRLEIEAETDRVTGMNKGISSIPINLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANTDLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYVGVVNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHIADRMGTPHLQKVLNQQLTNHIRDTLPNFRNKLQGQLLSIEHEVEAYKNFKPEDPTRKTKALLQMVQQFAVDFEKRIEGSGDQVDTLELSGGAKINRIFHERFPFEIVKMEFNEKELRREISYAIKNIHGIRTGLFTPDMAFEAIVKKQIVKLKGPSLKSVDLVIQELINTVKKCTKKLANFPRLCEETERIVANHIREREGKTKDQVLLLIDIQVSYINTNHEDFIGFANAQQRSSQVHKKTTVGNQVIRKGWLTISNIGIMKGGSKGYWFVLTAESLSWYKDDEEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVAENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRRDEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRPGPLPPFPSSSDSFGAPPQVPSRPTRAPPSVPSRRPPPSPTRPTIIRPLESSLLD dyn1_human Dynamin-1 DNM1 DNM protein protein human Homo sapiens Human MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQASPSRPESPRPPFDL dnm3-1 3282862 N/A 3282867 unspecified role unspecified role unspecified role unspecified role Region 1-754 Region 1-754 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dnm3-2 3282863 N/A 3282867 unspecified role unspecified role unspecified role unspecified role Region 1-754 Region 1-754 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dnm3-3 3282864 N/A 3282867 unspecified role unspecified role unspecified role unspecified role Region 1-754 Region 1-754 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false Q9UQ16-2:p.[Ile481Asp;His677Asp;Leu678Ser] I481D/H677D/L678S mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dnm3-4 3282865 N/A 3282867 unspecified role unspecified role unspecified role unspecified role Region 1-754 Region 1-754 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dnm1-18 3282866 N/A 3282868 unspecified role unspecified role unspecified role unspecified role Q05193:p.[Ile481Asp;His687_Leu688delinsAspSer] I481D/H687D/L688S mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Region 6-746 Region 6-746 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false