DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ xiao-2015-1 in vitro In vitro solid state nmr solid state nmr ssnmr solid state nmr predetermined predetermined participant predetermined Xiao Y., Ma B., McElheny D., Parthasarathy S., Long F., Hoshi M., Nussinov R., Ishii Y. DIP original experiment: DIP-266042X Nature structural & molecular biology 2015 IMEx Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Xiao Y., Ma B., McElheny D., Parthasarathy S., Long F., Hoshi M., Nussinov R., Ishii Y. Only protein-protein interactions imex curation xiao-2015-2 in vitro In vitro tem transmission electron microscopy tem predetermined predetermined participant predetermined Xiao Y., Ma B., McElheny D., Parthasarathy S., Long F., Hoshi M., Nussinov R., Ishii Y. DIP original experiment: DIP-266043X Nature structural & molecular biology 2015 IMEx Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Xiao Y., Ma B., McElheny D., Parthasarathy S., Long F., Hoshi M., Nussinov R., Ishii Y. Only protein-protein interactions imex curation xiao-2015-3 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Xiao Y., Ma B., McElheny D., Parthasarathy S., Long F., Hoshi M., Nussinov R., Ishii Y. DIP original experiment: DIP-266044X Nature structural & molecular biology 2015 IMEx Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Xiao Y., Ma B., McElheny D., Parthasarathy S., Long F., Hoshi M., Nussinov R., Ishii Y. Only protein-protein interactions imex curation p05067-pro_0000000092 Amyloid-beta protein 42 Alzheimer disease amyloid protein Cerebral vascular amyloid peptide APP A4 AD1 ABPP PreA4 Protease nexin-II APPI Amyloid precursor protein Amyloid-beta A4 protein Alzheimer disease amyloid A4 protein homolog Amyloid-beta (A4) precursor protein protein protein human Homo sapiens Human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 672 713 app-app-107 3278538 N/A 3278541 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3278541 unspecified role unspecified role unspecified role unspecified role in vitro In vitro direct interaction direct interaction false false false app-app-108 3278539 N/A 3278541 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3278541 unspecified role unspecified role unspecified role unspecified role in vitro In vitro direct interaction direct interaction false false false app-app-109 3278540 N/A 3278541 unspecified role unspecified role unspecified role unspecified role Region 1-40 Region 1-40 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3278541 unspecified role unspecified role unspecified role unspecified role Region 1-40 Region 1-40 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro direct interaction direct interaction false false false