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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3259701">
                <names>
                    <shortLabel>bartesaghi-2013-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="24154805" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="4CC8" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nsmb.2711" refType="primary-reference" refTypeAc="MI:0358"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-255682X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21887" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>3d-em</shortLabel>
                        <fullName>3D electron microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">3D-EM</alias>
                        <alias typeAc="MI:1041" type="synonym">electron tomog</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0410" refType="identity" refTypeAc="MI:0356"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608522" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Bartesaghi A., Merk A., Borgnia MJ., Milne JL., Subramaniam S.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-255682X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2013</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Bartesaghi A.,  Merk A.,  Borgnia MJ.,  Milne JL.,  Subramaniam S.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3259702">
                <names>
                    <shortLabel>q3zlh6_9hiv1</shortLabel>
                    <fullName>Envelope glycoprotein gp160</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Env polyprotein</alias>
                    <alias typeAc="MI:0301" type="gene name">env</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q3ZLH6" version="60" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903908" secondary="positive regulation of plasma membrane raft polarization" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903911" secondary="positive regulation of receptor clustering" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090527" secondary="actin filament reorganization" version="TrEMBL_112"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16079654" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019062" secondary="virion attachment to host cell" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0020002" secondary="host cell plasma membrane" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044175" secondary="host cell endosome membrane" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019031" secondary="viral envelope" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019064" secondary="fusion of virus membrane with host plasma membrane" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0075512" secondary="clathrin-dependent endocytosis of virus by host cell" version="TrEMBL_112"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60554N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030683" secondary="mitigation of host immune response by virus" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055036" secondary="virion membrane" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005198" secondary="structural molecule activity" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019082" secondary="viral protein processing" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0039654" secondary="fusion of virus membrane with host endosome membrane" version="TrEMBL_112"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000777" version="TrEMBL_112"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037527" version="TrEMBL_112"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000328" version="TrEMBL_112"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903905" secondary="positive regulation of establishment of T cell polarity" version="TrEMBL_112"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036377" version="TrEMBL_112"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="11676">
                    <names>
                        <shortLabel>9hiv1</shortLabel>
                        <fullName>Human immunodeficiency virus 1</fullName>
                    </names>
                </organism>
                <sequence>MIVMGTQRNYQHLLRWGTMILGLIIICSAADNLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIPLENVTEEFNMWKNKMVEQMHTDIISLWDQSLQPCVKLTPLCVTLNCTDATNGTIGNITDEMKGEIKNCSFNITTEIRDKKQKVYSLFYRLDVVPIEPDSSNSSRNSSEYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDKEFNGTGKCKNVSTVQCTHGIKPVVSTQLLLNGSLAEGEVRIRSENITNNAKTIIVQLVEPVRINCTRPNNNTRESVRIGPGQAFFATGDIIGDIRQAHCNVSRSQWNKTLQQVAAQLGEHFKNKAITFNSSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTWKANNGTWKANISESNNTEITLQCRIKQIINMWQRTGQAIYAPPIQGVIRCESNITGLLLTRDGGEGNNESEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRARRRVVGREKRAVGIGAVFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQSNLLRAIEAQQHMLKLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTNVPWNSSWSNKSHDEIWNNMTWLQWDKEISNYTNLIYSLIEESQNQQEKNEQDLLALDKWASLWNWFDISKWLWYIKIFIMIVGGLIGLRIVFAVLAVIKRVRQGYSPVSFQIHNPNPGGLDRPGRIEEEGGEPGRGRSIRLVSGFLALAWDDLRNLCLFSYHRLRDFALIVARTVELLGHSSLKGLRLGWEGLKYLWNLLVYWSQELKTSAINLVDTIAIAVAGWTDRVIEIGQGIGRAFLHIPRRIRQGLERALL</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21887-1" id="3259703">
                <names>
                    <shortLabel>env-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-192423E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16079670" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21887-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3259701</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3259704">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16079674" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3259702</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3259705">
                                <names>
                                    <shortLabel>Region 33-863</shortLabel>
                                    <fullName>Region 33-863</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16079675" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
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                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
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                                            </xref>
                                        </startStatus>
                                        <begin position="33"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
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                                            </xref>
                                        </endStatus>
                                        <end position="863"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
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