<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3254143">
                <names>
                    <shortLabel>li-2013-40</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="23676677" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3ZE3" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3ZE4" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16058130" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3ZE5" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature12179" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-252892X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21102" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Li D., Lyons JA., Pye VE., Vogeley L., Aragão D., Kenyon CP., Shah ST., Doherty C., Aherne M., Caffrey M.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-252892X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2013</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Crystal structure of the integral membrane diacylglycerol kinase.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Li D.,  Lyons JA.,  Pye VE.,  Vogeley L.,  Aragão D.,  Kenyon CP.,  Shah ST.,  Doherty C.,  Aherne M.,  Caffrey M.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3254144">
                <names>
                    <shortLabel>kdgl_ecoli</shortLabel>
                    <fullName>Diacylglycerol kinase</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">dgk</alias>
                    <alias typeAc="MI:0305" type="locus name">JW4002</alias>
                    <alias typeAc="MI:0305" type="locus name">b4042</alias>
                    <alias typeAc="MI:0301" type="gene name">dgkA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Diglyceride kinase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P0ABN1" version="63" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblbacteria" id="BAE78044" version="SP_122" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_122"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16058144" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UYO" version="SP_122"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_122"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_418466.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UXW" version="SP_122"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BRB" version="SP_122"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033718" version="SP_122"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000002907.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5D57" version="SP_122"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004143" secondary="diacylglycerol kinase activity" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UXX" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BRR" version="SP_122"/>
                    <secondaryRef db="ensemblbacteria" id="b4042" version="SP_122" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006654" secondary="phosphatidic acid biosynthetic process" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DWK" version="SP_122"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036945" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4CJZ" version="SP_122"/>
                    <secondaryRef db="ensemblbacteria" id="AAC77012" version="SP_122" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ZE4" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ZE5" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4BPD" version="SP_122"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q2M6R2" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2KDC" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5D56" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4D2E" version="SP_122"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_122"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000829" version="SP_122"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009411" secondary="response to UV" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UXZ" version="SP_122"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P00556" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ZE3" version="SP_122"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60228N"/>
                    <secondaryRef db="ensemblbacteria" id="AAC77012" version="SP_122" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5D6I" version="SP_122"/>
                    <secondaryRef db="ensemblbacteria" id="BAE78044" version="SP_122" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblbacteria" id="BAE78044" version="SP_122" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4CK0" version="SP_122"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UP6" version="SP_122"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_122"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="83333">
                    <names>
                        <shortLabel>ecoli</shortLabel>
                        <fullName>Escherichia coli (strain K12)</fullName>
                    </names>
                </organism>
                <sequence>MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAVLIAIIVAVITWCILLWSHFG</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21102-1" id="3254145">
                <names>
                    <shortLabel>dgka-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-190955E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16058184" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21102-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3254143</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3254146">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16058188" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3254144</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
