<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3247880">
                <names>
                    <shortLabel>cheung-2012-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="23185017" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-251852X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.1206530109" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20736" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16025228" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Cheung EC., Ludwig RL., Vousden KH.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251852X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Cheung EC.,  Ludwig RL.,  Vousden KH.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3247881">
                <names>
                    <shortLabel>cheung-2012-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="23185017" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-251853X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.1206530109" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16025245" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20736" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Cheung EC., Ludwig RL., Vousden KH.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251853X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Cheung EC.,  Ludwig RL.,  Vousden KH.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3247882">
                <names>
                    <shortLabel>cheung-2012-3</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="23185017" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-251854X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.1206530109" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16025262" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20736" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Cheung EC., Ludwig RL., Vousden KH.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251854X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Cheung EC.,  Ludwig RL.,  Vousden KH.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3247883">
                <names>
                    <shortLabel>hxk2_human</shortLabel>
                    <fullName>Hexokinase-2</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Hexokinase type II</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Muscle form hexokinase</alias>
                    <alias typeAc="MI:0301" type="gene name">HK2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Hexokinase-B</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P52789" version="SP_73" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HG1" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006002" secondary="fructose 6-phosphate metabolic process" version="SP_207"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000290573" version="SP_207" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008637" secondary="apoptotic mitochondrial changes" version="SP_207"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UN82" version="SP_73" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043129" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005739" secondary="mitochondrion" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035795" secondary="negative regulation of mitochondrial membrane permeability" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006096" secondary="glycolytic process" version="SP_207"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019807" version="SP_207"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-50110N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008865" secondary="fructokinase activity" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001678" secondary="cellular glucose homeostasis" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019158" secondary="mannokinase activity" version="SP_207"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-741469" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8WU87" version="SP_73" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061621" secondary="canonical glycolysis" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990830" secondary="cellular response to leukemia inhibitory factor" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004396" secondary="hexokinase activity" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_207"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6W5J2" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_207"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022673" version="SP_207"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NZT" version="SP_207"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HFU" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000378" secondary="negative regulation of reactive oxygen species metabolic process" version="SP_207"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001312" version="SP_207"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000290573" version="SP_207" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-70171" version="SP_207"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022672" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046324" secondary="regulation of glucose import" version="SP_207"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HEX" version="SP_207"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000159399" version="SP_207" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072656" secondary="maintenance of protein location in mitochondrion" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904925" secondary="positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045766" secondary="positive regulation of angiogenesis" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007595" secondary="lactation" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005741" secondary="mitochondrial outer membrane" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005536" secondary="glucose binding" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002931" secondary="response to ischemia" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004340" secondary="glucokinase activity" version="SP_207"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000180.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051156" secondary="glucose 6-phosphate metabolic process" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072655" secondary="establishment of protein localization to mitochondrion" version="SP_207"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P52789" version="SP_207"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_207"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLGLDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKGAALITAVACRIREAGQR</sequence>
            </interactor>
            <interactor id="3247884">
                <names>
                    <shortLabel>tigar_human</shortLabel>
                    <fullName>Fructose-2,6-bisphosphatase TIGAR</fullName>
                    <alias typeAc="MI:0301" type="gene name">TIGAR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">C12orf5</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TP53-induced glycolysis and apoptosis regulator</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TP53-induced glycolysis regulatory phosphatase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NQ88" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002931" secondary="response to ischemia" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006915" secondary="apoptotic process" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903301" secondary="positive regulation of hexokinase activity" version="SP_158"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DCY" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_158"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001345" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009410" secondary="response to xenobiotic stimulus" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901215" secondary="negative regulation of neuron death" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010332" secondary="response to gamma radiation" version="SP_158"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013078" version="SP_158"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000078237" version="SP_158" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071279" secondary="cellular response to cobalt ion" version="SP_158"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000179259" version="SP_158" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006003" secondary="fructose 2,6-bisphosphate metabolic process" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005741" secondary="mitochondrial outer membrane" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004331" secondary="fructose-2,6-bisphosphate 2-phosphatase activity" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004083" secondary="bisphosphoglycerate 2-phosphatase activity" version="SP_158"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2R840" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5628897" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045820" secondary="negative regulation of glycolytic process" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" secondary="cellular response to DNA damage stimulus" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006914" secondary="autophagy" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000378" secondary="negative regulation of reactive oxygen species metabolic process" version="SP_158"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60093N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010666" secondary="positive regulation of cardiac muscle cell apoptotic process" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901525" secondary="negative regulation of mitophagy" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030388" secondary="fructose 1,6-bisphosphate metabolic process" version="SP_158"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000179259" version="SP_158" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043069" secondary="negative regulation of programmed cell death" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902153" secondary="regulation of response to DNA damage checkpoint signaling" version="SP_158"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_065108.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904024" secondary="negative regulation of glucose catabolic process to lactate via pyruvate" version="SP_158"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3920747" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043456" secondary="regulation of pentose-phosphate shunt" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060576" secondary="intestinal epithelial cell development" version="SP_158"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029033" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045739" secondary="positive regulation of DNA repair" version="SP_158"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-20736-1" id="3247885">
                <names>
                    <shortLabel>tigar-hk2-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-190388E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16025239" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20736-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3247880</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3247886">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025244" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247883</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3247887">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025243" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247884</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-20736-2" id="3247888">
                <names>
                    <shortLabel>tigar-hk2-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-190388E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20736-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16025256" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3247881</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3247889">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025261" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247883</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3247890">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025260" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247884</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-20736-3" id="3247891">
                <names>
                    <shortLabel>tigar-hk2-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-190388E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20736-3" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16025273" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3247882</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3247892">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025282" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247883</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3247893">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025277" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247884</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3247894">
                                <names>
                                    <shortLabel>Flag-tag</shortLabel>
                                    <fullName>Flag-tag</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025278" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>flag tag</shortLabel>
                                        <fullName>flag tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">FLAG-tagged</alias>
                                        <alias typeAc="MI:0303" type="go synonym">FLAG</alias>
                                        <alias typeAc="MI:0303" type="go synonym">DYKDDDDKV epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">DYKDDDDKV epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">FLAG</alias>
                                        <alias typeAc="MI:1041" type="synonym">FLAG-tagged</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0518" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456503" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                            <feature id="3247895">
                                <names>
                                    <shortLabel>Region 258-261</shortLabel>
                                    <fullName>Region 258-261</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16025280" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>required to bind</shortLabel>
                                        <fullName>necessary binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">required to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0429" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608898" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureDetectionMethod>
                                    <names>
                                        <shortLabel>deletion analysis</shortLabel>
                                        <fullName>deletion analysis</fullName>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureDetectionMethod>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="258"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="261"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
