DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ jasion-2012-1 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Jasion VS., Doukov T., Pineda SH., Li H., Poulos TL. DIP original experiment: DIP-253620X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Crystal structure of the Leishmania major peroxidase-cytochrome c complex. Jasion VS., Doukov T., Pineda SH., Li H., Poulos TL. Only protein-protein interactions imex curation jasion-2012-2 in vitro In vitro oxidoreduct assay oxidoreductase assay oxidoreduct assay predetermined predetermined participant predetermined Jasion VS., Doukov T., Pineda SH., Li H., Poulos TL. DIP original experiment: DIP-253621X Proceedings of the National Academy of Sciences of the United States of America 2012 IMEx Crystal structure of the Leishmania major peroxidase-cytochrome c complex. Jasion VS., Doukov T., Pineda SH., Li H., Poulos TL. Only protein-protein interactions imex curation q4qen5_leima LMJF_16_1310 LMJF_16_1320 protein protein leima Leishmania major MPPKARAPLPPGDVERGEKLFKGRAAQCHTATKGGSNGVGPNLFGIVNRPSGKVEGFTYSKANAESGVIWTPEVLDVYLENPKKFMPGTKMSFAGIKKPQERADVIAYLETLK q4q3k2_leima APX LMJF_34_0070 protein protein leima Leishmania major MSGTSRRAKGLFTGIAVGTFVSGAMFVSCASARVEEPPFDIRALRADIEDMISEKLELGPSLIRLAWHEAASYDCFKKDGSPNSASMRFKPECLYAGNKGLDIPRKALETLKKKYPQISYADLWVLAAYVAIEYMGGPTIPFCWGRVDAKDGSVCGPDGRLPDGSKTQSHVREVFRRLGFNDQETVALIGAHTCGECHIEFSGYHGPWTHDKNGFDNSFFTQLLDEDWVLNPKVEQMQLMDRATTKLMMLPSDVCLLLDPSYRKYVELYAKDNDRFNKDFANAFKKLTELGTRNLHKAPASES apx-q4qen5_leima-1 3246316 N/A 3246318 unspecified role unspecified role unspecified role unspecified role Region 11-113 Region 11-113 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3246319 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false apx-q4qen5_leima-2 3246317 N/A 3246318 electron donor electron donor unspecified role unspecified role Region 11-113 Region 11-113 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false Q4QEN5:p.Arg24Ala R24A mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false Q4QEN5:p.[Arg24Ala;Lys98Ala] R24A/K98A mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Q4QEN5:p.Lys98Ala K98A mutation decreasing rate mutation decreasing interaction rate mutation decreasing rate alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3246319 electron acceptor electron acceptor unspecified role unspecified role ecolx Escherichia coli redox reaction oxidoreductase activity electron transfer reaction redox reaction false false false