DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ tzur-2011-1 in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting western blot western blot Immuno blot Immuno blot Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250588X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation tzur-2011-2 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250593X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation tzur-2011-3 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250591X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation tzur-2011-4 in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250589X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation tzur-2011-5 caeel Caenorhabditis elegans anti tag coip anti tag coimmunoprecipitation anti tag coip ms participant Identification by mass spectrometry ms participant Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250594X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation tzur-2011-6 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250592X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation tzur-2011-7 in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting predetermined predetermined participant predetermined Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. DIP original experiment: DIP-250590X PLoS biology 2011 IMEx LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. Tzur YB., Egydio de Carvalho C., Nadarajan S., Van Bostelen I., Gu Y., Chu DS., Cheeseman IM., Colaiácovo MP. Only protein-protein interactions imex curation lab1_caeel Long arms of the bivalent protein 1 lab-1 C03D6.6 protein protein caeel Caenorhabditis elegans MVSHKKNDRPRPLWILKIHKRLSLFEFKRYATGIGKDDGQDISWVLKGNAKNNVYQVTVETMENCETDECKKVIWVPDELAESTGTMFEDFKEDQPQESVSSISNNEANWGSSVNELDENYEKMQKEETFDPYDSDSDTSEDSDFDEDFEDSDKTMCSGQS glc7a_caeel Serine/threonine-protein phosphatase PP1-alpha CeGLC-7-alpha Glc seven-like phosphatase 1 F29F11.6 gsp-1 protein protein caeel Caenorhabditis elegans MSNDGDLNIDNLITRLLEVRGCRPGKPVTMSEAEIRALCHKSREIFLSQPILLELEAPLKICGDIHGQYNDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRFSIKLWKTFTDCFNCLPIAALIDEKIFCCHGGLSPDLQNMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPDVVAKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYQGMNSGRPAVGGGRPGTTAGKK glc7b_caeel Serine/threonine-protein phosphatase PP1-beta Glc seven-like phosphatase 2 gsp-2 CeGLC-7-beta F56C9.1 Ce-glc-7beta CeGLC-7beta glc-7 protein protein caeel Caenorhabditis elegans MDVEKLNLDNIISRLLEVRGSKPGKNVQLTESEIKGLCQKSREIFLSQPILLELEAPLKICGDVHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGSMMTVDETLMCSFQILKPADKKKYPYGAGGVGSNRPVTPPRNAPAAQPKKGAKK a9ujn7_caeel maph-1.2 CELE_F25D7.4 F25D7.4 protein protein caeel Caenorhabditis elegans MPEEYIMSSKACIYVLGGAANTAALFDFDGVYILDGGFAEKNPGFVAHVRDVSAVLLAAPTLGNLGTTSALLEQGKPLPVFTNTKPFKTAKPGSSGEIAKAIQEANSKLLSVAPPLFNPKYPAHIIYQSAAKGVLSMYILAGDVKDSDMITKALAGGNEAEVEKAAAENGTIGVLLWRPAMTDQSAVRVLISGTSSLARIQQSLDKAAKSLPFLNAPTVKSKDALLGIPAPAVPRPVAGKPSTRSASTTGAARTRPAVPAVSAPRALTSRAPAGPARPTTTRSATPATRTAVPPRATAPPKAAPASKAPTRAPIPARSAPAPPRGAPAKAPKAEPIAQKKVAGKVQRAAPSKPASAVSAPKATAPASTSSAPATAPEASRRDPNDVTIVLDDSLFPEDFNQGSAPMDIVVIPPTPEPPRLEEARATHPKEPIVDAEDLAKAPHEVDDVANLADVEDEIPPPVDAFKKPEPRPETNVAGGSGEDRISEPVDAFKKPDPVELDDFDPLKPSHPDPSAPVVPSGDLIIATPDPELPNIVAAVPFIPPSPKGPNDGLVKLDDELEKIAPGFEEPLIPQAPRDDGTLAEFNEDVSKLVDISMDTNSAEVAADLAKAVGEVTQLSAELQNLALDEKTDEYVRKLSNQMIEDATLPFTSALASSIVTSNGSETNGHGEQAHAAQNGGIKIPKHDLMQSHSNVIENGAAVKYEKTDPALDAVLNACAQESEQIDASHPENLHMPAAPGSVASAKPVKFARPYYFDVVTVPRNEKLETSVEADGLQEFISKVRSRNVILASKEISGEQLQSILRGKQTWCDRAHPCNVIPTHSSPMLHDFRQKNEEQFAANHLQFSMPVEKQRTTVSSDAGVVEYDLARVDLL q18494_caeel maph-1.3 C36A4.5 CELE_C36A4.5 protein protein caeel Caenorhabditis elegans MPEEYIMSSKACVYVLGGAANTATLFDFDGVYILDGGFAEKSPGFVAHVRDVSAVLLAAPTLGNLGTTSALLEQGKPLPVFTNTKPFKTAKPGSSGEIAKAIQEANSKLLSVAPPLFSPKYPAHIIYQSAAKGVLSMYILAGDVKDSEVITKALAGGNEAEVEKAAAENGTIAVLLWRPAMTDQSAVRVLISGTSSLARIQQSLDKAAKSLPFLNAPTVKSKDALLDIPAPAVPRPVAGKPSTRSASTTGAARTRPAIPAVSAPRALTSRAPTGPACPTTTRSAAPATRTAVPPRATAPPKAASASKAPIRAPIPAKSAPAPPRGAPAKAAKAEAIAQKKVAGKVQRAAPSKPASAVSAPKATAPASTSSAPATAPEASRRDPSDVTIVLDDSLFPEDFNQGSAPMDIVVIPPTPEPPRLEEARATHPKEPIVDAEDLAKAPQEVDDVANLADVEDEIPPPVGAFKKPEPRPETIVAGGSGEDRIPEPVDAFKKPDPVELDDFDPLKPSHPDPSAPVVPSGHLIVATPDPELPNIVAAVPFIPPSPKGPNDGLVKLDDELEKIAPGFEEPLIPQAPRDDGTLAEFNEDVSKLVDISMDTNSSEVAADLTKAVGEVTQLSAELQNLALDEKTDEYVRKLSNQMIEDATLPFTSALASSIVTSNGSETNGHGEQAHAAQNGGIKIPKHDLMQSHSNVIENRAAVKYEKTDPALDAVLNACAQESEQIDASHPENLHMPAAPGSVASAKPVKFARPYYFDVVTVPRYEKLETSVEADGLQEFISKVRSRNVILSSKEISGEQLQAILRGKQTWCDRAHPCNVIPTHSSPMLHDFRQKNEEQFAANHLQFSMPVEKQRTTVSSDAGVVEYDLARVDLL crtc1_caeel CREB-regulated transcription coactivator 1 homolog crtc-1 Y20F4.2 protein protein caeel Caenorhabditis elegans MSNSNTPRKFSEKIAILERKQNEENTTFEDIMRQVQSITHHPTDSSGSSTATAPMPIPQQGLLPPQQPWGHNLGGSLPNVHQMPSYSPPQWPPNWQHEIQHRPIQGHRSRSPEDHMIGSASGSPSHHYHPYGMRSNGLSRSPDRTPPQHPQYTPYGPPYNQPGQLVPPESWNQINRARSDPAIHNMGGMVPMHPHHHQQQQMAFHQMPHYLQNSMPGPSGMMAPNSQSQQHSPQLTPQGSQQGSPVQMHHQIPPPLQMGNNQQMGGGNNGMSPLQSPNHMMTPMYGYHNGSPLHSPMDSPHASTLMLDGSGTPSPYMEVSPPGMHDFNQDAGSLPNLQNVQQQQQQQQEIYTNGGAPGGGYYHAPIGPRHSTGACGPRLVPGPALTPESQSAPTSPHNQLDPNQPPMWPTRTFSNSPEALDIPKLTITNAEGAPGHHVDSYNDFNDLGLDSLDSVLCNGAPPQTISNHQTPNNSFHDPGGTQMLQN o18034_caeel CELE_T05F1.5 T05F1.5 protein protein caeel Caenorhabditis elegans MDRSSDGSKFIEGRVKIGRKRYRFSAEKFLCFSDDSDDEPPIQISGKPASTAKPTSGSPQHHPQPIEQATTNPSVTSSLINQHNRVGNNQGHRSPSPTSSPQLSSPPPSTMVDSLSTHSESSRSNIFETTRNTSHRQQGLDLVEDDVAGTLQVDRALEKSVKMKRVWTGSTPWSPFQLDCSCLTVTCDGFSSKFKRQRVGASSGRFSWFKINTSKPTDAEMVYSKARRNGLSIRELEHDAIPSKLSEFAFHFYTFAVSDEDVSKVNRLIDEDFVGAFNADTLLKNPAQSFFFHNIDQKDVIALCALATHYNLHSVVPPLPPMQLLENDQNILEVIDNQTTMQHLENYLSKKAMEHLARLKTELEHL pid4_caeel Protein pid-4 piRNA-induced silencing defective protein 4 W03G9.2 pid-4 protein protein caeel Caenorhabditis elegans MNTHNARDSDDESPLESEEHLKRFFAGRNLYSQTKIDDARKKSHDAKYAKEVEWDAKDTAKGKPVFKKYRQEIADKTSRCDAQFINNLHTYYGNGSELRELPETHYAVDFMGTTIATTEMTAELKKLKVLKKKTATSQFVREHRQLGFIPTPSRRSLSCTGRFMNFETKCDERPDRTNPEFSVGNNNFLSATISNLDEDFKTPSNCEHVASIVPKEISNALTALIPHVNVFDYEKGEMEIGKVLCSNKNLHAYVIPKQHDQEQMLKDFSARFLAWYNKLSHLQRDTFGTDKDPKRSGKQEDGKPMKPYFWRVNVILCLQEFQEEGTMFRRARHVCGIRPHKSQPGLDLYIEIDTGSMRALKTNYLTVRKLPQEFANVPTPILEVRFEGAKTEEDVARRIAHIRKTGRAYIKSFDTGKRKIYQNSFFNGQPKDWSNIETAVLLPPKESSMSKLFCEDRDCMGLCCTDQWLENAESSPGISTIPASWIADKNKKPFVDRSPQKFKFPASGSYMKPAN gls2_caeel Putative glutaminase 2 glna-2 L-glutamine amidohydrolase DH11.1 protein protein caeel Caenorhabditis elegans MTSKPTTQKSVMYRIPSERTLESLHEMIGSRMSKMSLKNTLRGISNPYERDENEGSEDMIFELFKIPNKNEASIGKLLTVLRQLGLRDDDPRLVPMMEKIKDFEKIAEEKCSEATEQKHWKLTKEQFKECIAPSIDIVSRALQTDMVIPNWVTFVDQIRTLFNECKEIREGQVATYIPQLARQSPNLWAVSLCTVDGQRASFGDVKHPFCVQSVSKAFNYAIVASDLGADVVHSYVGQEPSGRLFNEICLDSTNKPHNPMVNSGAIVITSLIKSKTNMADRFDFVLNQYRKIAGNEFIGFNNATFLSERATADRNYALSYFMKENRCFPKETESLTDALDFYFQLCSVEVTCESLAVMASTLANGGVCPITNETCVDPNPCRDVLSLMYSCGMYDASGQFSFNVGLPAKSGVSGAMIVVVPNVMGICLFSPPLDSLGNSCRGVAFCKKLVSTFNFHNYDCLVHNSNIKSDPRRRDIRERDRLIPVFHVARAGDLPTMRRLYMQGEDLNTSDHDDRTVLHIAATEGYETMIKFLVNVAKVDVDKKDRWGRTPLDEAKFFKHDHVSRFLEKAMKRPEQHRKDSVSSLDTDDEIDDDGFPEKPSFTID q20981_caeel Major sperm protein F58E6.5 CELE_F58E6.5 protein protein caeel Caenorhabditis elegans MTTAPDLTKVVFNPSKSVTFAPVEKKQAVSIEVINNSTSDVAVKFKNTGPNVYKTQPPQAKIGVGEKKVFKCIFKGLPKEKCKTNDRFTVVYIAASKNVVIEKAWKNAHKTCTMKHKIAILFQGVNDQKENETQQPTNNDDDEDKDRQGQLRSKSKVETAKGKKATVVMFVRKEGDSVSDEEDDEGAVEGAEHTNPAGVATSNEAGNMSELRTTRPAGAFTGVVASNDNPMSELRTTRPAGNFSGQTASTPGGAVDPKSMGLKTTRPAGAFTGQVASNGSTDGQELRTTKPAGTYDNPQKKNQK pth2_caeel Probable peptidyl-tRNA hydrolase 2 C24G6.8 protein protein caeel Caenorhabditis elegans MSENIPDIDPNELLPNAPGQHQDLGVDNPPEPDNASIRAERGSPTPSSVTVDNAPSLPDRSFSHLPINDPFSGEIPEVPIPSSAISISSQALSDPVPTPSDTSRPGILRNDEQGSTSSHPVDPQEPNEVNNEYLAHLLDLGFDEYTAVLALKRTNSAGVEQAVAWIVERSNESDFDEDSSSSENEADEEMGAVQSVAGRTHKMVLVANMSLKMGTGKIAAQVGHATLGVYRQAMNSENGQNAIAAWTRHGQVKIVVKGQSTEQLMDLCKVAKDAGCYYYLVQDAGYTQIPAGSRTVLGIFGTVEQVDSVTGGLKLL o01820_caeel htp-3 F57C9.5 CELE_F57C9.5 protein protein caeel Caenorhabditis elegans MDESFDSSVVPGSLTSDDRAIFNEQTLKNGDENSKSSLEVMANCVYLANSTILRERKVIPAEYFQDFQVYGDVSGYTLRQDIPEGRSVSSKLLASHDAIRQKLLQKLAIVVEESLNTNPVETFVWTFVYDSTTSASAEIGYGGRKSKFVVNYLNMDDTAQQFCKMFSELRNVLSLLRPLPRGLIPSMKVAYRGEPEFVPGFQQVDDFVNPEQINLGAVSFPHGNGFQFAYASKFMVEQPSAIRPPVEVSHFEDDLLNSTITPIEVVRDNTMNCAENPELDEIYFSPGRQEVRMDEDVANESIRCNPSMASEMMVLQSEYNVLIADNDEVPMVVERERSPIVKAAKKRSTRAPAVPITPTEPASPVESPVKEQPQKAPKAQMRRSSKRTTKNNERCEQKEEEPIVNPKRRSARRLVPPVEVDEQPEEQNDDDAQNSLQIDSDAQNSLQIDSDAIITSPEKRNESKSAIPEEAADLDNTTSEKQESSTARYGVSNTSINRKKPDPVANPVSEEAQVDLANGSIPDKRPRKRKYGRVSSILDVADLPTDDTVEEDVRESPIYGRVPSILDVARAEENDAQNDAQDAQNEIAVEGLADLSIDTEQHEEAAPINVTGHQSESVPIIVTEHQSEEAQTVVTEQPAGAASVIAAERHYGRVSSILDVAGSFADVDPSGAAPAIATERHYGRVSSILDVAGSLSDVDPQEDTESSTQNQSTSKKFKPNPPKAMRYGQSPNMPSRRGN sydc_caeel Aspartate--tRNA ligase, cytoplasmic dars-1 Aspartyl-tRNA synthetase drs-1 B0464.1 protein protein caeel Caenorhabditis elegans MADAAEGEQPKLSKKELNKLARKAKKDEKAGEKGGNQQQAAAMDQEDASKDFYGSYGLVNSKEKKVLNFLKVKEINVSNATKDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKFVSSISKESIVDVYATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEKASEQENQLAVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPSEGGANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDLEMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLILKYPDAITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDERYSNSYDMFMRGEEILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGGGIGLERVTMLFLGLHNIRLASLFPRDPKRLTP pncb_caeel Nicotinate phosphoribosyltransferase nprt-1 Y54G2A.17 protein protein caeel Caenorhabditis elegans MSFILPSESIDGTHPCNGLHMNGQDSLVQPLLTDFYQITMCYAYWKTGTHNEPAVFDVFFRKNPFQGEFTVFAGLEDCLRFVENFKFSQSDIDYVKKILPENAEPEFYEYLETLNGSHLTIEAVAEGSVVFPKVPLLTINGPLAMCQLIETSILNLVNYASLVATNAARFRQASGWKIQLLEFGLRRAQGPNGGLTASKYCYIGGFDATSNVLAGKLYGIPVKGTQAHSFICSFSSPAELKVRLLNHKITNEKADLFQISMEKRAWLLDQFSWKAALSEVSDGELSAFVAYAIAFPDTFLALIDTYDVIRSGVVNFVAVSLALHDLGYRSMGCRIDSGDLSYLSKELRECFVKVSTLKGEYKFFEKMSIVASNDINEETIMSLNDQQHEINAFGVGTHLVTCQKQPALGCVYKLVAQSAQPKIKLSQDVTKITIPGKKKCYRIFGKNGYAILDLMMLEDEPEPQPNQQILCRHPFEESKRALVNANKIIKLHNVYWKDGEMITPLPTLNEIKEHVNESIRSTLRQDHRRYLNPTPYKVSVSERLYQFLHTLWLQNAPIGQLE g5efv4_caeel Y48B6A.14 hmg-1.1 CELE_Y48B6A.14 protein protein caeel Caenorhabditis elegans MAKAAAGKKASPVKRVKKGGKAKDPNAPKRAMSAFFFWMQENRERIKKPGMGVADVAKAAGVEWGKLTDKSRWEKKAADDKKRYEVDIANYKKSQ uba5_caeel Ubiquitin-like modifier-activating enzyme 5 uba-5 T03F1.1 protein protein caeel Caenorhabditis elegans MSDEQIDKLVSRLDGALNRLGNVKKDHPLESSSNSKPTHQPKSPAPYRQKIEKLSAEVVDSNPYSRLMALQRMGIVNEYERIREKTVAVVGVGGVGSVVAEMLTRCGIGKLILFDYDKVEIANMNRLFYQPNQAGLSKVEAARDTLIHVNPDVQIEVHNFNITTMDNFDTFVNRIRKGSLTDGKIDLVLSCVDNFEARMAVNMACNEENQIWMESGVSENAVSGHIQYIEPGKTACFACVPPLVVASGIDERTLKRDGVCAASLPTTMAVVAGFLVMNTLKYLLNFGEVSQYVGYNALSDFFPRDSIKPNPYCDDSHCLQRQKEYEEKVANQPVDLEVEVPEEETVVHEDNEWGIELVNESEPSAEQSSSLNAGTGLKFAYEPIKRDAQTELSPAQAATHDFMKSIKDKLVEEAQNKGK q95xc8_caeel htp-2 CELE_Y73B6BL.2 Y73B6BL.2 protein protein caeel Caenorhabditis elegans MAPLENNYNESLNKSKDAIDDKTWSKLFPSIVSDPDRSSNFMIRAIYVVFSAVLRQRNILEKEYFSKNYITENLSCMTLSFKNLRAHQIAQLLRAAGDATKDGFLKEISLVVTEHDGDVEAIEVFSMKFIYFENGGVVARLSTDNNDQEDPHFAELAQLRYEGAESVRDQMVTIVRSVQFLCTKVLEPLPAEFTANFRLKYTNDAPSNFRIDGFDDSSTFYTLPDGIQSVTIGHLRPGHHAAHMQCWSKSMSDSYAAELTLKGHLDKVSDMYAFNPVNVLYKSFNSEDTDPGLSQDTTESANDQGGNVTSPVDNITDSLEKTQMSPIKMRPTTRRGADDSKTRSSPYSRSRK q20305_caeel htp-1 CELE_F41H10.10 F41H10.10 protein protein caeel Caenorhabditis elegans MAPLETIYDESLNKSADSIDDKKWSKLFPRIVSDPDRSSNFMTRAIYVAFSAVLRNRNILGQEYFTKNYITEKLKCMTLCFRNPRSNQIAQLLRNAGDATKDGFLKEVSLVITNNEGDLEAIEVFSMKFIYFENGGVVARLSTDKNGQEDPHFAKLAQLVYEGGDSVRDQMVTIVRSVQFLCTKVLEPLPEEFTANFRLEYTNDAPSNFRIDGFEDSSTFYTLPDDIQSATIGHLRPGCHAANMECWSMLMSDSYEAELTLKRHLDKVSDRHGFNPVNVLYKSFNSEDSDTSLSQATTESVNDQGGNETSPVDDITESLEKAQMSPIQTRPTTRRGADGSKTRSSPYSRSCK q8wqe8_caeel F56C9.11 lab-2 CELE_F56C9.11 protein protein caeel Caenorhabditis elegans MPPHPSTTWKDYMLDNLKIEGETLKRASEEQVINTVVDVLRDIGFNLPNLKIVVQKFGYMPDDDSEVDQRYYVCFEVDSNSSAEMFEQRHGKTKKIHRMNKKSSEMDHKKWLKLKQYIGFNAEIIQKTLREAKRIMSEHPYPSSDGFRLTCNRNMIVLYFDDKKESTINIEQLARNYRKVFDKAIESLSEQARNTINRLILMEPNTQKRGISDETVSNASPPEKSPRLVNSPMPAMNQLLSPILPN g5ebg0_caeel him-3 CELE_ZK381.1 ZK381.1 protein protein caeel Caenorhabditis elegans MATKEQIVEHRESEIPIASQWKATFPVDLEIEKNSEMFALRYIKCASAFILDRRGILDEKCFKTRTIDKLLVTAFQSSVPAAKRVSSTFDGLRDAIQQGYLREFAIVFYKKPNEEDINEVFAFRFAYGDEGEIFVSLNNGIDTNESSQELLQAKFVDTDNTKQMFASTIKKLHRCIKKMEPLPQGSDASFRVSYTEKAPKDYTPEGYLLSPMFYTLNQDIRKASIGIVCGGHHKIQMLAASQYLKQDFDLDKTTTLNPNMSIMANQSKRKGRISRDSPYGLSQGITKKNKD gsp_1-lab_1-1 3244605 N/A 3244612 unspecified role unspecified role prey prey ecolx Escherichia coli N/A 3244613 unspecified role unspecified role bait bait ecolx Escherichia coli direct interaction direct interaction false false false lab_1-gsp_2-1 3244606 N/A 3244614 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3244612 unspecified role unspecified role bait bait Q17604:p.[Val73Ala;Trp75Ala] V73A/W75A mutation increasing strength mutation increasing interaction strength mutation increasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false p.Lys72_Trp75del Δ72-75 mutation increasing strength mutation increasing interaction strength mutation increasing strength deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false lab_1-gsp_1-1 3244607 N/A 3244612 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3244613 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false lab_1-gsp_1-2 3244608 N/A 3244612 unspecified role unspecified role bait bait Q17604:p.[Val73Ala;Trp75Ala] V73A/W75A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3244613 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction false false false lab_1-crtc_1-1 3244609 N/A 3244615 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244616 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244617 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244618 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244619 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244620 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244621 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244622 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244623 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244624 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244625 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244626 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244627 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244628 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244629 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244630 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244631 unspecified role unspecified role prey prey caeel Caenorhabditis elegans N/A 3244612 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false caeel Caenorhabditis elegans association association false false false lab_1-lab_1-1 3244610 N/A 3244612 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3244612 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false gsp_2-lab_1-1 3244611 N/A 3244614 unspecified role unspecified role bait bait ecolx Escherichia coli N/A 3244612 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction false false false