DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ deng-2012-3 in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250402X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-4 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250396X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-5 ecolx Escherichia coli comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel weight by comassie molecular weight estimation by coomasie staining weight by comassie Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250399X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-6 in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250405X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-7 in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250404X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-8 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250397X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-9 in vitro In vitro crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250400X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-10 ecolx Escherichia coli solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250398X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-11 in vitro In vitro crosslink cross-linking study crosslink weight by comassie molecular weight estimation by coomasie staining weight by comassie Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250401X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation deng-2012-12 in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. DIP original experiment: DIP-250403X Structure (London, England : 1993) 2012 IMEx The structure of dimeric apolipoprotein A-IV and its mechanism of self-association. Deng X., Morris J., Dressmen J., Tubb MR., Tso P., Jerome WG., Davidson WS., Thompson TB. Only protein-protein interactions imex curation apoa4_human Apolipoprotein A-IV APOA4 Apolipoprotein A4 protein protein human Homo sapiens Human MFLKAVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES apoa4-apoa4-1 3240066 N/A 3240076 unspecified role unspecified role unspecified role unspecified role K104-CL K104-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3240076 unspecified role unspecified role unspecified role unspecified role K97-CL K97-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-1 3240067 N/A 3240076 unspecified role unspecified role unspecified role unspecified role Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-2 3240068 N/A 3240076 unspecified role unspecified role unspecified role unspecified role Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false P06727:p.[His182Gly;Ala183Gly;Asp184Gly] H182G/A183G/D184G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-apoa4-2 3240069 N/A 3240076 unspecified role unspecified role unspecified role unspecified role K198-CL K198-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3240076 unspecified role unspecified role unspecified role unspecified role K253-CL K253-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-apoa4-3 3240070 N/A 3240076 unspecified role unspecified role unspecified role unspecified role K99-CL K99-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3240076 unspecified role unspecified role unspecified role unspecified role K247-CL K247-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-3 3240071 N/A 3240076 unspecified role unspecified role unspecified role unspecified role Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false P06727:p.[His182Gly;Ala183Gly;Asp184Gly] H182G/A183G/D184G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-4 3240072 N/A 3240076 unspecified role unspecified role unspecified role unspecified role P06727:p.Glu283Cys E283C mutation mutation certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-5 3240073 N/A 3240076 unspecified role unspecified role unspecified role unspecified role Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false P06727:p.[His182Gly;Ala183Gly;Asp184Gly] H182G/A183G/D184G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-6 3240074 N/A 3240076 unspecified role unspecified role unspecified role unspecified role P06727:p.Asn171Cys N171C mutation mutation certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false apoa4-apoa4-4 3240075 N/A 3240076 unspecified role unspecified role unspecified role unspecified role K209-CL K209-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3240076 unspecified role unspecified role unspecified role unspecified role K247-CL K247-CL cross linker cross linker crosslinker crosslinker modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain false Region 84-355 Region 84-355 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false