DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ gibbings-2012-1 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255473X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-2 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255482X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-3 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255477X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-4 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255486X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-5 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255488X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-6 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255474X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255478X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-8 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255487X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-9 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255475X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-10 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255483X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-11 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255479X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-12 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255484X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-13 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255476X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-14 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255480X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-15 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255481X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation gibbings-2012-16 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. DIP original experiment: DIP-255485X Nature structural & molecular biology 2012 IMEx Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes. Gibbings D., Leblanc P., Jay F., Pontier D., Michel F., Schwab Y., Alais S., Lagrange T., Voinnet O. Only protein-protein interactions imex curation ago2_human Protein argonaute-2 AGO2 Argonaute RISC catalytic component 2 EIF2C2 Eukaryotic translation initiation factor 2C 2 PAZ Piwi domain protein Protein slicer protein protein human Homo sapiens Human MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA ago1_human Protein argonaute-1 AGO1 Argonaute RISC catalytic component 1 EIF2C1 Eukaryotic translation initiation factor 2C 1 Putative RNA-binding protein Q99 protein protein human Homo sapiens Human MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA tnr6a_human Trinucleotide repeat-containing gene 6A protein TNRC6A CAGH26 KIAA1460 TNRC6 CAG repeat protein 26 Glycine-tryptophan protein of 182 kDa GW182 autoantigen EMSY interactor protein protein protein human Homo sapiens Human MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSNNGTSTATSTNNNAKRATANNQQPQQQQQQQQPQQQQPQQQPQPQPQQQQPQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSALTNQQPQNNGEVQNSKNQSDINHSTSGSHYENSQRGPVSSTSDSSTNCKNAVVSDLSEKEAWPSAPGSDPELASECMDADSASSSESERNITIMASGNTGGEKDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGPWGFSHGAIISTCQVSVDAPESKSESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTNLPSVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAKTGGTVESDGSTESTGRLEEKGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDPKPALRWGDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTSSFTWGNNINPNNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQVHQLLTPASAISNKEASSGSGWGEPWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAASSTSTWGSSSVGPQALSKSGPKSMQDGWCGDDMPLPGNRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIAGLGMQNLNSVRQNGNPSMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQQGRPLSVQQQMMQQSRQLDPNLLVKQQTPPSQQQPLHQPAMKSFLDNVMPHTTPELQKGPSPINAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSISVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLWGTPHYSTSLWGPPSSSDPRGISSPSPINAFLSVDHLGGGGESM prio_human Major prion protein PrP27-30 PrP33-35C ASCR PRNP PRIP PRP ALTPRP protein protein human Homo sapiens Human MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG q9upy3-1 Endoribonuclease Dicer DICER1 DICER HERNA KIAA0928 Helicase with RNase motif protein protein human Homo sapiens Human MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRTSSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGNQLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAVMPGTTDTIQVLKGRMDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYEDDFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS ago2_mouse Protein argonaute-2 Ago2 Argonaute RISC catalytic component 2 Eif2c2 Eukaryotic translation initiation factor 2C 2 Kiaa4215 Piwi/argonaute family protein meIF2C2 Protein slicer protein protein mouse Mus musculus Mouse MYSGAGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA prio_mesau Major prion protein PrP27-30 PrP33-35C PRNP PRP protein protein mesau Mesocricetus auratus (Golden hamster) Golden hamster MANLSYWLLALFVAMWTDVGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGTWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPMMHFGNDWEDRYYRENMNRYPNQVYYRPVDQYNNQNNFVHDCVNITIKQHTVTTTTKGENFTETDIKIMERVVEQMCTTQYQKESQAYYDGRRSSAVLFSSPPVILLISFLIFLMVG prp Prion Octarepeat peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) GSRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGLE dicer_mouse Endoribonuclease Dicer Dicer1 Dicer Mdcr Double-strand-specific ribonuclease mDCR-1 protein protein mouse Mus musculus Mouse MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLNPHAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSDLEVNASWTKERWSQEFTKHQVLIMTCYVALTVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCESCPSCPRILGLTASILNGKCDPEELEEKIQKLERILRSDAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEAALDFINDCNVAVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTLLRKIHALCEEYFSPASLDLKYVTPKVMKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSADGAEADVHAGVDDEDAFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMDSVRLAERVVALICCEKLHKIGELDEHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELITRLHQYIFSHILRLEKPALEFKPTGAESAYCVLPLNVVNDSGTLDIDFKFMEDIEKSEARIGIPSTKYSKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPVDFRYPNLDFGWKKSIDSKSFISTCNSSLAESDNYCKHSTTVVPEHAAHQGATRPSLENHDQMSVNCKRLPAESPAKLQSEVSTDLTAINGLSYNKNLANGSYDLVNRDFCQGNQLNYFKQEIPVQPTTSYPIQNLYNYENQPKPSNECPLLSNTYLDGNANTSTSDGSPAVSTMPAMMNAVKALKDRMDSEQSPSVGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNSEKWEKDEMTKDCLLANGKLGEACEEEEDLTWRAPKEEAEDEDDFLEYDQEHIQFIDSMLMGSGAFVRKISLSPFSASDSAYEWKMPKKASLGSMPFASGLEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSREKALDPAQENGSSQQKSLSGSCAAPVGPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFETFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVKFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMQPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS tnr6a_mouse Trinucleotide repeat-containing gene 6A protein Tnrc6a Kiaa1460 protein protein mouse Mus musculus Mouse MRELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQKIKVPEQIKPSVSQPQPANSDNGTSTATSTNNNAKRATASNQQPPPPQQQQPQQEQQQQQPQALPRYPREVPPRFRHQEHKQLLKRGQHFPVIAANLGSAVKVLNSQSESSAVTNQQPQNNGEVQNSKSQSDINHNTSGSHYENCQRGPVSSTSDCSTSCKNAVNDLLEKEAWPSAPGSDPELAPECIDADSASNSESERNITVMASGNTGGEKDGLRNSTGLGSQSKFVVGSSSNNVGHGSSTGPWGFPHGALISTCQVSVDAPESKPESSNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQNINSKVSGSSTHGTWGSLQETCEPEVSGTQKVSFSGQPQNITTETTGPNNTTNFMTSSLPNSGSVQNNELPTSNPGAWRVSTMNHPQIQAPSVMNGTSLSHLSNGESKTGGSYGTTWGAYGSNYSGDKCAGPNGQANGDTVNATLMQPGINGPMGTNFQVNTNKGGGVWEPGTVNSQSSPWGSGNGANSGGSRRGWGSPAQNTGTGLSSVEWNKLPSNQHSNDSANGNGKKLTNGWKSTEEDDQGSATSQTNEQNSVWAKAGGTVESDGSAESTGRLEEKVTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQTPIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACTDKTSPNSNDTSSVSGWGDPKPTLRWGDSKGSNCQGGWEDDSAATGMIKSNQWGGCKEDKSTWNDSQKSKQGWGDGQKSSQGWSISAGDNWGESSRSNHWGEANKKSSSGGSDSDRSISGWNELGKTSSFTWGNNINPNNSSGWDESSKPNSSQGWGDPPKCNQSLGWGDSSKPVSSPDWNKQQDIVGSWGIPPATSKPPGTGWLGGPIPAPAKEEEPTGWEEPSPESIRRKMEIDDGTSAWGDPSKYNYKNVNMWNKNIPEASGRSDQQAQMHRLLPAASAVSSKETSSGSGWGEPWAEPSTPATTVDNGTSAWGKPIDSGPSWGEPITAASNASTWGSSSVGPQSLSKSGPKSMQDGWCGDDMPLPGSRPTGWEEEEDVEIGMWNSNSSQELNSSLNWPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEDAWINPFVKQFSNISFSRDSPEENVQSNKMDLSGGMLQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMERNPYFDKNGNPNMFGVGNTAAQPRGMQQPPAQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNGGLNPLFGPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSAPSANRQQQDQQGRPLSVQQQMMQQSRQLDPSLLVKQQTPPSQQPLHQPAMKSFLDNVMPHTTPELQKGPSPVNAFSNFPIGLNSNLNVNMDMNSIKEPQSRLRKWTTVDSMSVNTSLDQNSSKHGAISSGFRLEESPFVPYDFMNSSTSPASPPGSIGDGWPRAKSPNGSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINSLSINTVREVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPGSVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRVGGGWGNSDARYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQSLGSSQSRLGSLDCSHSFSSRTDVNHWNGAGLSGANCGDLHGTSLWGTPHYSTSLWGPPSSDPRGISSPSPINAFLSVDHLGGGGESM tnrc6a-ago1-1 3239271 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239288 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239289 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false ago1-prnp-1 3239272 N/A 3239288 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3239290 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false dicer1-ago2-2 3239273 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239290 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239291 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false ago2-prnp-1 3239274 N/A 3239292 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3239293 unspecified role unspecified role prey prey P04273:p.[Ala113Val;Ala115Val;Ala118Val] A113V/A115V/A118V mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false mouse Mus musculus Mouse physical association physical association false false false prp-ago1-1 3239275 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239288 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239294 unspecified role unspecified role bait bait prp:p.[Trp12Ala;Trp20Ala;Trp28Ala;Trp36Ala;Trp44Ala] W12A/W20A/W28A/W36A/W44A mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength alanine scanning alanine scanning certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli association association false false false tnrc6a-ago2-1 3239276 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239289 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false tnrc6a-ago2-2 3239277 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239290 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239289 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false prnp-ago2-1 3239278 N/A 3239292 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3239293 unspecified role unspecified role bait bait P04273:p.[Ala113Val;Ala115Val;Ala118Val] A113V/A115V/A118V mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false mouse Mus musculus Mouse physical association physical association false false false prnp-ago2-2 3239279 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239290 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3239291 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239289 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false prnp-dicer1-1 3239280 N/A 3239295 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3239296 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3239290 unspecified role unspecified role bait bait mouse Mus musculus Mouse association association false false false prnp-dicer1-2 3239281 N/A 3239289 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239290 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3239291 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false prnp-ago2-3 3239282 N/A 3239292 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3239290 unspecified role unspecified role bait bait P04156:p.Ala117Val A117V mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false mouse Mus musculus Mouse physical association physical association false false false prnp-ago2-4 3239283 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239290 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3239291 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false prnp-ago2-5 3239284 N/A 3239287 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3239290 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false ago2-prnp-2 3239285 N/A 3239287 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3239290 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false ago2-prnp-3 3239286 N/A 3239292 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3239290 unspecified role unspecified role prey prey P04156:p.Ala117Val A117V mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false mouse Mus musculus Mouse physical association physical association false false false