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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
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            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3238341">
                <names>
                    <shortLabel>west-2012-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22451934" refType="primary-reference" refTypeAc="MI:0358"/>
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                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-251587X" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>saxs</shortLabel>
                        <fullName>x ray scattering</fullName>
                        <alias typeAc="MI:1041" type="synonym">saxs</alias>
                    </names>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">West AL., Evans SE., González JM., Carter LG., Tsuruta H., Pozharski E., Michel SL.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251587X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">West AL.,  Evans SE.,  González JM.,  Carter LG.,  Tsuruta H.,  Pozharski E.,  Michel SL.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3238342">
                <names>
                    <shortLabel>west-2012-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22451934" refType="primary-reference" refTypeAc="MI:0358"/>
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                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3QSI" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">West AL., Evans SE., González JM., Carter LG., Tsuruta H., Pozharski E., Michel SL.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251588X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">West AL.,  Evans SE.,  González JM.,  Carter LG.,  Tsuruta H.,  Pozharski E.,  Michel SL.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3238343">
                <names>
                    <shortLabel>nikr_helpy</shortLabel>
                    <fullName>Putative nickel-responsive regulator</fullName>
                    <alias typeAc="MI:0305" type="locus name">HP_1338</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O25896" version="SP_50" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" secondary="regulation of transcription, DNA-templated" version="SP_136"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027271" version="SP_136"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002145" version="SP_136"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016151" secondary="nickel cation binding" version="SP_136"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR010985" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WVC" version="SP_136"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_208130.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_136"/>
                    <secondaryRef db="ensemblbacteria" id="AAD08380" version="SP_136" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblbacteria" id="AAD08380" version="SP_136" refType="transcript"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_136"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CA9" version="SP_136"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001217" secondary="DNA-binding transcription repressor activity" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CAJ" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3QSI" version="SP_136"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LGH" version="SP_136"/>
                    <secondaryRef db="ensemblbacteria" id="HP_1338" version="SP_136" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032993" secondary="protein-DNA complex" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WVF" version="SP_136"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022988" version="SP_136"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000380787.1"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-3711N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010045" secondary="response to nickel cation" version="SP_136"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013321" version="SP_136"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="O25896"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WVD" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2CAD" version="SP_136"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2WVE" version="SP_136"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6MRJ" version="SP_136"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-528005" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
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                </interactorType>
                <organism ncbiTaxId="85962">
                    <names>
                        <shortLabel>helpy</shortLabel>
                        <fullName>Helicobacter pylori</fullName>
                        <alias typeAc="MI:1041" type="synonym">Campylobacter pylori</alias>
                    </names>
                </organism>
                <sequence>MDTPNKDDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLRGVKFAKLTKASSFEYNE</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-20654-1" id="3238344">
                <names>
                    <shortLabel>nikr_helpy-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-5483E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15976266" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20654-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3238341</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3238345">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15976270" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3238343</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-20654-2" id="3238346">
                <names>
                    <shortLabel>nikr_helpy-2</shortLabel>
                </names>
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                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-5483E" refType="identity" refTypeAc="MI:0356"/>
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                <experimentList>
                    <experimentRef>3238342</experimentRef>
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                <participantList>
                    <participant id="3238347">
                        <names>
                            <shortLabel>N/A</shortLabel>
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                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15976288" refType="identity" refTypeAc="MI:0356"/>
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                        <interactorRef>3238343</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3238348">
                                <names>
                                    <shortLabel>Region 58-148</shortLabel>
                                    <fullName>Region 58-148</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15976289" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
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                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
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                                        </startStatus>
                                        <begin position="58"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
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                                        </endStatus>
                                        <end position="148"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
