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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3237629">
                <names>
                    <shortLabel>no-2012-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22392982" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3RBM" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15973158" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20644" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.1118215109" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-251555X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3RYW" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">No JH., de Macedo Dossin F., Zhang Y., Liu YL., Zhu W., Feng X., Yoo JA., Lee E., Wang K., Hui R., Freitas-Junior LH., Oldfield E.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251555X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">No JH.,  de Macedo Dossin F.,  Zhang Y.,  Liu YL.,  Zhu W.,  Feng X.,  Yoo JA.,  Lee E.,  Wang K.,  Hui R.,  Freitas-Junior LH.,  Oldfield E.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3237630">
                <names>
                    <shortLabel>a5k4u6_plavs</shortLabel>
                    <alias typeAc="MI:0306" type="orf name">PVX_092040</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="A5K4U6" version="41" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MAV" version="TrEMBL_94"/>
                    <secondaryRef db="ensemblprotists" id="EDL45674" version="TrEMBL_94" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15973171" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60027N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HNA" version="TrEMBL_94"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RBM" version="TrEMBL_94"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008299" secondary="isoprenoid biosynthetic process" version="TrEMBL_94"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_001615401.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016765" secondary="transferase activity, transferring alkyl or aryl (other than methyl) groups" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HN9" version="TrEMBL_94"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033749" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HN8" version="TrEMBL_94"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000092" version="TrEMBL_94"/>
                    <secondaryRef db="ensemblprotists" id="EDL45674" version="TrEMBL_94" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3PH7" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EZ3" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RYW" version="TrEMBL_94"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008949" version="TrEMBL_94"/>
                    <secondaryRef db="ensemblprotists" id="PVX_092040" version="TrEMBL_94" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LDW" version="TrEMBL_94"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039702" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3CC9" version="TrEMBL_94"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HN7" version="TrEMBL_94"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="126793">
                    <names>
                        <shortLabel>Plasmodium vivax (strain Salvador I)</shortLabel>
                        <fullName>Plasmodium vivax (strain Salvador I)</fullName>
                    </names>
                </organism>
                <sequence>MKETNSEEADSGLAFFRNMYDKYRDAFLSHLNEYSLEEEIKEHISKYYKLLFDYNCLGGKNNRGILVILIYEYVKNRDINSSEWEKAACLAWCIEILQAAFLVADDIMDKGETRRNKYCWYLLKDVETKNAVNDVLLLYNSIYKLIEIYLRNESCYVDVIATFRDATLKTIIGQHLDTNIFSDKYSDAHREIDVNNINVPEQPVININMINFGVYKNIVIHKTAYYSFFLPIVCGMLLAGIAVDNLIYKKIEDISMLMGEYFQIHDDYLDIFGDSTKTGKVGSDIQNNKLTWPLIKTFELCSEPDKIKIVKNYGKNNLACVKVIDSLYEQYKIRKHYESYEKAQKAKILSAINELHHEGIEYVLKYLLEILFTGV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-20644-1" id="3237631">
                <names>
                    <shortLabel>a5k4u6_plavs-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-190252E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20644-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15973196" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3237629</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3237632">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15973200" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3237630</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
