DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ peisley-2011-1 in vitro In vitro tem transmission electron microscopy tem predetermined predetermined participant predetermined Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. DIP original experiment: DIP-253802X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. Only protein-protein interactions imex curation peisley-2011-2 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. DIP original experiment: DIP-253803X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. Only protein-protein interactions imex curation peisley-2011-3 in vitro In vitro light scattering light scattering predetermined predetermined participant predetermined Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. DIP original experiment: DIP-253804X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. Only protein-protein interactions imex curation peisley-2011-4 in vitro In vitro emsa electrophoretic mobility shift assay Gel retardation assay band shift band shift Gel retardation assay emsa predetermined predetermined participant predetermined Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. DIP original experiment: DIP-253805X Proceedings of the National Academy of Sciences of the United States of America 2011 IMEx Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Peisley A., Lin C., Wu B., Orme-Johnson M., Liu M., Walz T., Hur S. Only protein-protein interactions imex curation ifih1_human Interferon-induced helicase C domain-containing protein 1 Helicase with 2 CARD domains Interferon-induced with helicase C domain protein 1 Melanoma differentiation-associated protein 5 Murabutide down-regulated protein RNA helicase-DEAD box protein 116 RIG-I-like receptor 2 IFIH1 MDA5 RH116 Clinically amyopathic dermatomyositis autoantigen 140 kDa protein protein human Homo sapiens Human MSNGYSTDENFRYLISCFRARVKMYIQVEPVLDYLTFLPAEVKEQIQRTVATSGNMQAVELLLSTLEKGVWHLGWTREFVEALRRTGSPLAARYMNPELTDLPSPSFENAHDEYLQLLNLLQPTLVDKLLVRDVLDKCMEEELLTIEDRNRIAAAENNGNESGVRELLKRIVQKENWFSAFLNVLRQTGNNELVQELTGSDCSESNAEIENLSQVDGPQVEEQLLSTTVQPNLEKEVWGMENNSSESSFADSSVVSESDTSLAEGSVSCLDESLGHNSNMGSDSGTMGSDSDEENVAARASPEPELQLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQLKNQIQEPCKKFAIADATREDPFKEKLLEIMTRIQTYCQMSPMSDFGTQPYEQWAIQMEKKAAKEGNRKERVCAEHLRKYNEALQINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDSDEGGDDEYCDGDEDEDDLKKPLKLDETDRFLMTLFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGVIEHETVNDFREKMMYKAIHCVQNMKPEEYAHKILELQMQSIMEKKMKTKRNIAKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSDED ifih1-1 3234072 N/A 3234076 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli physical association physical association false false false ifih1-9 3234073 N/A 3234076 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli physical association physical association false false false ifih1-10 3234074 N/A 3234076 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli physical association physical association false false false ifih1-11 3234075 N/A 3234076 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli physical association physical association false false false