IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ korzelius-2011-1 caeel Caenorhabditis elegans anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Korzelius J., The I., Ruijtenberg S., Prinsen MB., Portegijs V., Middelkoop TC., Groot Koerkamp MJ., Holstege FC., Boxem M., van den Heuvel S. S.J.L.vandenHeuvel@uu.nl PLoS genetics 2011 imex curation Only protein-protein interactions korzelius-2011-2 caeel Caenorhabditis elegans anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Korzelius J., The I., Ruijtenberg S., Prinsen MB., Portegijs V., Middelkoop TC., Groot Koerkamp MJ., Holstege FC., Boxem M., van den Heuvel S. S.J.L.vandenHeuvel@uu.nl PLoS genetics 2011 imex curation Only protein-protein interactions korzelius-2011-3 caeel-larva Immature form of the adult worm larva Immature form of an organism fluorescence imaging fluorescence microscopy fluorescence imaging immunohistochemistry immunohistochemistry Korzelius J., The I., Ruijtenberg S., Prinsen MB., Portegijs V., Middelkoop TC., Groot Koerkamp MJ., Holstege FC., Boxem M., van den Heuvel S. S.J.L.vandenHeuvel@uu.nl PLoS genetics 2011 imex curation Only protein-protein interactions ccne_caeel G1/S-specific cyclin-E cye-1 C37A2.4 protein protein caeel Caenorhabditis elegans MAGRKSSRTAERVPTTQKPERKSAILSPHDELRERLLETAIDMKENIPQRNTRNSSVGSQKSDCSETRKRRSTKEGPAAKRHSGEKHRNGSREDSLEYISEYSDDREVGSSSSQSSRTRGQPLPAMPEEEEVFDKSSSSDNLAESEESHEMVRLEERQDIEEEIEDDFDDEEEDVVNDKEEYEEIESEDEDDYPVQNEGFAVTKRLMNDEHMVTAPTFLSTAKCDGIGSPTKVWSLMVKRDEIPRATRFLLGNHPDMDDEKRRILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKYEEIYPPKCIDFAHLTDSAFTCDNIRTMEVLIVKYIGWSLGPITSIQWLSTYLQLLGTGKKNKSDHYEEQNMYVPELLRSEYLEMCKILDFLLFEIDSFTFSYRTIAAAVLFVNYEPTCAVEKATGFMQAQLEKVIEYVEPVCRAFAKQRQLLDDVIPKHESIKSDDSHNIQVYVKRSSMEPIVKSERERIQHLKARRLHPQRLF cdk2_caeel Cyclin-dependent kinase 2 Cell division protein kinase 2 K03E5.3 cdk-2 protein protein caeel Caenorhabditis elegans MSREIRSLESIISDARENTHEKMLIRKQRDMTTDIAPERDLQGRFCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFDIIYANSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQNILVSDSGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEIASNKPLFPGECEISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVFPQWPVNLKKLEETSCLTGNGLDVLREILRYPPERRLTAKGALSHRYFLQNGFTQNRPSVTDLMKDIRAQNRTPPLLNNHQEKSIF cdk_2-cye_1-1 2972287 N/A 2972290 unspecified role unspecified role prey prey N/A 2972291 unspecified role unspecified role bait bait region venus venus fluorescent protein tag venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false O61847:p.Thr55_Tyr56delinsAlaPhe mutation mutation certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Supp. 2D Both proteins expressed from the myo-3 promoter (Pmyo-3) to drive expression of Cyclins and CDKs in muscle cye_1-cdk_2-1 2972288 N/A 2972290 unspecified role unspecified role bait bait N/A 2972291 unspecified role unspecified role prey prey region venus venus fluorescent protein tag venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false O61847:p.Thr55_Tyr56delinsAlaPhe mutation mutation certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Supp. 2D Both proteins expressed from the myo-3 promoter (Pmyo-3) to drive expression of Cyclins and CDKs in muscle cye_1-cdk_2-2 2972289 N/A 2972290 unspecified role unspecified role neutral component neutral component N/A 2972291 unspecified role unspecified role neutral component neutral component region venus venus fluorescent protein tag venus undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false O61847:p.Thr55_Tyr56delinsAlaPhe mutation mutation certain certain sequence position certain certain certain sequence position certain false colocalization colocalization false false false Supp. 2C Both proteins expressed from the myo-3 promoter (Pmyo-3) to drive expression of Cyclins and CDKs in muscle