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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3229923">
                <names>
                    <shortLabel>hansen-2011-3</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="21874019" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3SPH" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3SPC" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16184" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3SPJ" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3SPI" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature10370" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3SPG" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-218916X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15942308" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="4922">
                        <names>
                            <shortLabel>picpa</shortLabel>
                            <fullName>Pichia pastoris (Yeast)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Yeast</alias>
                            <alias typeAc="MI:1041" type="synonym">Pichia pastoris</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Hansen SB., Tao X., MacKinnon R.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-218916X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2011</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Hansen SB.,  Tao X.,  MacKinnon R.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3229924">
                <names>
                    <shortLabel>kcj12_chick</shortLabel>
                    <fullName>ATP-sensitive inward rectifier potassium channel 12</fullName>
                    <alias typeAc="MI:0301" type="gene name">KCNJ12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Inward rectifier K(+) channel Kir2.2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Potassium channel, inwardly rectifying subfamily J member 12</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="F1NHE9" version="SP_48" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016449" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KUM" version="SP_66"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005242" secondary="inward rectifier potassium channel activity" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SPC" version="SP_66"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040445" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SPH" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M84" version="SP_66"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_004945227.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013518" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3JYC" version="SP_66"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D2YW45" version="SP_48" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006813" secondary="potassium ion transport" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SPI" version="SP_66"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_015149865.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013673" version="SP_66"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031224" secondary="intrinsic component of membrane" version="SP_66"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-59161N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034765" secondary="regulation of ion transmembrane transport" version="SP_66"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSGALP00000007506" version="SP_66" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990573" secondary="potassium ion import across plasma membrane" version="SP_66"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_66"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014756" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5KUK" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SPJ" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M85" version="SP_66"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSGALG00000004721" version="SP_66" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSGALT00000007518" version="SP_66" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003272" version="SP_66"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15942324" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SPG" version="SP_66"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_004945226.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" secondary="protein homotetramerization" version="SP_66"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M86" version="SP_66"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_66"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9031">
                    <names>
                        <shortLabel>chick</shortLabel>
                        <fullName>Gallus gallus (Chicken)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Chicken</alias>
                    </names>
                </organism>
                <sequence>MTAGRVNPYSIVSSEEDGLRLTTMPGINGFGNGKIHTRRKCRNRFVKKNGQCNVEFTNMDDKPQRYIADMFTTCVDIRWRYMLLLFSLAFLVSWLLFGLIFWLIALIHGDLENPGGDDTFKPCVLQVNGFVAAFLFSIETQTTIGYGFRCVTEECPLAVFMVVVQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVAMRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRITEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEINEDSPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLASEILWGHRFEPVLFEEKNQYKVDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSTNSFCYENELAFMSRDEDEEDDDSRGLDDLSPDNRHEFDRLQATIALDQRSYRRESEI</sequence>
                <attributeList>
                    <attribute name="caution" nameAc="MI:0618">This sequence has been withdrawn from Uniprot.</attribute>
                    <attribute name="crc64">E0AF2D60A03D06C1</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-16184-1" id="3229925">
                <names>
                    <shortLabel>kir2.2-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-187185E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16184-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15942363" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3229923</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3229926">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15942367" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3229924</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="4922">
                                <names>
                                    <shortLabel>picpa</shortLabel>
                                    <fullName>Pichia pastoris (Yeast)</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Yeast</alias>
                                    <alias typeAc="MI:1041" type="synonym">Pichia pastoris</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
