DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ huang-2011-2 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219173X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-3 mouse Mus musculus Mouse anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219178X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-4 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219171X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-5 mouse Mus musculus Mouse 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219175X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-6 in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219176X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219174X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-8 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219172X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation huang-2011-9 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. DIP original experiment: DIP-219177X Nature 2011 IMEx Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Huang W., Ghisletti S., Saijo K., Gandhi M., Aouadi M., Tesz GJ., Zhang DX., Yao J., Czech MP., Goode BL., Rosenfeld MG., Glass CK. Only protein-protein interactions imex curation senp3_mouse Sentrin-specific protease 3 Senp3 Smt3ip Smt3ip1 SUMO-1-specific protease 3 Sentrin/SUMO-specific protease SENP3 Smt3-specific isopeptidase 1 protein protein mouse Mus musculus Mouse MKETIQGTGSWGPEPPGPGTTYSNPRRERLRWPLPPKPRLKSGGGFGPDPGSGTTVPTRRLPAPRPSFDASASEEEEEEEEEDEEEVAAWRLPPRWGQLGASQRSRALRPSHRKTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPQEGGATPQVPSPCCRFDSPRGLPPPRLGLLGALMAEDGMRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGLSGPEGERSLAPPDASILISNVCSIGDHVAQELFQSSDLGIAEEADRTGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKSLVLQLIQSYQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV nr1h2_human Oxysterols receptor LXR-beta Ubiquitously-expressed nuclear receptor Nuclear receptor NER Liver X receptor beta Nuclear receptor subfamily 1 group H member 2 NR1H2 LXRB NER UNR protein protein human Homo sapiens Human MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE senp3_human Sentrin-specific protease 3 SENP3 SSP3 SUSP3 SUMO-1-specific protease 3 Sentrin/SUMO-specific protease SENP3 protein protein human Homo sapiens Human MKETIQGTGSWGPEPPGPGIPPAYSSPRRERLRWPPPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEEDEDEEEEVAAWRLPPRWSQLGTSQRPRPSRPTHRKTCSQRRRRAMRAFRMLLYSKSTSLTFHWKLWGRHRGRRRGLAHPKNHLSPQQGGATPQVPSPCCRFDSPRGPPPPRLGLLGALMAEDGVRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGQSGPEGERSLAPPDASILISNVCSIGDHVAQELFQGSDLGMAEEAERPGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRMPGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV cor2a_human Coronin-2A CORO2A IR10 WDR2 WD repeat-containing protein 2 protein protein human Homo sapiens Human MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTENELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL kcc2g_human Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK CAMK-II CAMK2G CAMKG protein protein human Homo sapiens Human MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKKRKSSSSVHLMPQSNNKNSLVSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKGRVPEGRSSRDRTAPSAGMQPQPSLCSSAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ cor2a_mouse Coronin-2A Coro2a protein protein mouse Mus musculus Mouse MSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELIGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLGIVLQEASYKGHRANKVLFLGSLKKLLSTGTSRWNNRQMALWDQENLSVPLTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSMEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSGMNRGPIMMSLRPGSELLDSQTLPPERPLSNSMVQVSPQPLEPMKQPAEDGDQAPFSLLEEKLAKWTAEHHLGEKSCLTNGFDVFECSPPKTENELLQMFYRQQEEIRRLRELLIQREVQTKQLELEIKNLRMALGQL senp3-nr1h2-1 3222754 N/A 3222762 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3222763 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false P55055:p.Ser426Ala S426A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false mouse Mus musculus Mouse physical association physical association false false false nr1h2-senp3-1 3222755 N/A 3222764 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse N/A 3222763 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false mouse Mus musculus Mouse physical association physical association false false false coro2a-nr1h2-1 3222756 N/A 3222763 unspecified role unspecified role prey prey P55055:p.[Lys409Arg;Lys447Arg] K409R/K447R mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3222765 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false coro2a-nr1h2-2 3222757 N/A 3222765 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3222763 unspecified role unspecified role prey prey mouse Mus musculus Mouse physical association physical association false false false camk2g-nr1h2-1 3222758 N/A 3222766 enzyme enzyme unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm N/A 3222763 enzyme target enzyme target substrate substrate unspecified role unspecified role ecolx Escherichia coli phosphorylation phosphorylation reaction phosphorylation false false false coro2a-nr1h2-3 3222759 N/A 3222763 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3222765 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false coro2a-nr1h2-4 3222760 N/A 3222767 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3222763 unspecified role unspecified role prey prey Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false P55055:p.Ser426Asp S426D mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false mouse Mus musculus Mouse physical association physical association false false false nr1h2-coro2a-1 3222761 N/A 3222765 unspecified role unspecified role prey prey in vitro In vitro N/A 3222763 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli physical association physical association false false false