DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ yuan-2011-6 in vitro In vitro density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218740X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions imex curation yuan-2011-7 in vitro In vitro 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218741X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions imex curation yuan-2011-8 in vitro In vitro density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218742X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions imex curation yuan-2011-9 in vitro In vitro 3d-em 3D electron microscopy 3D-EM electron tomog predetermined predetermined participant predetermined Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. DIP original experiment: DIP-218743X Structure (London, England : 1993) 2011 IMEx Structure of the Drosophila apoptosome at 6.9 å resolution. Yuan S., Yu X., Topf M., Dorstyn L., Kumar S., Ludtke SJ., Akey CW. Only protein-protein interactions imex curation q7kli1_drome Dark Ark Ark-RB Hac1 dapaf-1L APAF-1 APAF1 ARK Apaf-1 Apaf-I Apaf1 D-Apaf-1 DARK Dapaf-1 Dmel\CG6829 HAC-1 HAC1 Hac-1 T1 anon-53Fa apaf-1 apaf1 arc ark dAPAF-1 dApaf-1 dApaf1 dArk dapaf dapaf-1 dapaf-1S dark hac-1 hac1 l(2)SH0173 CG6829 Dmel_CG6829 Apaf protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MDFETGEHQYQYKDILSVFEDAFVDNFDCKDVQDMPKSILSKEEIDHIIMSKDAVSGTLRLFWTLLSKQEEMVQKFVEEVLRINYKFLMSPIKTEQRQPSMMTRMYIEQRDRLYNDNQVFAKYNVSRLQPYLKLRQALLELRPAKNVLIDGVLGSGKTWVALDVCLSYKVQCKMDFKIFWLNLKNCNSPETVLEMLQKLLYQIDPNWTSRSDHSSNIKLRIHSIQAELRRLLKSKPYENCLLVLLNVQNAKAWNAFNLSCKILLTTRFKQVTDFLSAATTTHISLDHHSMTLTPDEVKSLLLKYLDCRPQDLPREVLTTNPRRLSIIAESIRDGLATWDNWKHVNCDKLTTIIESSLNVLEPAEYRKMFDRLSVFPPSAHIPTILLSLIWFDVIKSDVMVVVNKLHKYSLVEKQPKESTISIPSIYLELKVKLENEYALHRSIVDHYNIPKTFDSDDLIPPYLDQYFYSHIGHHLKNIEHPERMTLFRMVFLDFRFLEQKIRHDSTAWNASGSILNTLQQLKFYKPYICDNDPKYERLVNAILDFLPKIEENLICSKYTDLLRIALMAEDEAIFEEAHKQVQRFDDRVWFTNHGRFHQHRQIINLGDNEGRHAVYLHNDFCLIALASGQILLTDVSLEGEDTYLLRDESDSSDILRMAVFNQQKHLITLHCNGSVKLWSLWPDCPGRRHSGGSKQQLVNSVVKRFIGSYANLKIVAFYLNEDAGLPEANIQLHVAFINGDVSILNWDEQDQEFKLSHVPVLKTMQSGIRCFVQVLKRYYVVCTSNCTLTVWDLTNGSSNTLELHVFNVENDTPLALDVFDERSKTATVLLIFKYSVWRLNFLPGLSVSLQSEAVQLPEGSFITCGKRSTDGRYLLLGTSEGLIVYDLKISDPVLRSNVSEHIECVDIYELFDPVYKYIVLCGAKGKQVVHVHTLRSVSGSNSHQNREIAWVHSADEISVMTKACLEPNVYLRSLMDMTRERTQLLAVDSKERIHLIKPAISRISEWSTITPTHAASNCKINAISAFNDEQIFVGYVDGVIIDVIHDTALPQQFIEEPIDYLKQVSPNILVASAHSAQKTVIFQLEKIDPLQPNDQWPLMMDVSTKYASLQEGQYIILFSDHGVCHLDIANPSAFVKPKDSEEYIVGFDLKNSLLFLAYENNIIDVFRLIFSCNQLRYEQICEEEIAQKAKISYLVATDDGTMLAMGFENGTLELFAVENRKVQLIYSIEEVHEHCIRQLLFSPCKLLLISCAEQLCFWNVTHMRNNQLEREQKRRRSRRHKQHSVTQEDAVDAAPIAADIDVDVTFVADEFHPVNRGTAELWRNKRGNAIRPELLACVKFVGNEARQFFTDAHFSHFYAIDDEGVYYHLQLLELSRLQPPPDPVTLDIANQYEDLKNLRILDSPLMQDSDSEGADVVGNLVLEKNGGVARATPILEEASS dronc_drome Caspase Dronc Dronc NEDD2-like caspase Nc CG8091 protein protein drome Drosophila melanogaster (Fruit fly) Fruit fly MQPPELEIGMPKRHREHIRKNLNILVEWTNYERLAMECVQQGILTVQMLRNTQDLNGKPFNMDEKDVRVEQHRRLLLKITQRGPTAYNLLINALRNINCLDAAVLLESVDESDSRPPFISLNERRTSRKSADIVDTPSPEASEGPCVSKLRNEPLGALTPYVGVVDGPEVKKSKKIHGGDSAILGTYKMQSRFNRGVLLMVNIMDYPDQNRRRIGAEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSVEGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLMEPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQVMADHAHDTDLEDILKKTSEAVGNKRTKKGSMQTGAYDNLGFNKKLYFNPGFFNE dark-1 3220724 N/A 3220728 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction false false false dark-2 3220725 N/A 3220728 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction false false false dark-dronc-1 3220726 N/A 3220729 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3220728 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction false false false dark-dronc-2 3220727 N/A 3220729 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3220728 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction false false false