DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dray-2010-1 in vitro In vitro pull down pull down weight by staining molecular weight estimation by staining weight by staining Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. DIP original experiment: DIP-217659X Nature structural & molecular biology 2010 IMEx Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. Only protein-protein interactions imex curation dray-2010-2 in vitro In vitro pull down pull down weight by staining molecular weight estimation by staining weight by staining Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. DIP original experiment: DIP-217661X Nature structural & molecular biology 2010 IMEx Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. Only protein-protein interactions imex curation dray-2010-3 in vitro In vitro pull down pull down weight by staining molecular weight estimation by staining weight by staining Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. DIP original experiment: DIP-217663X Nature structural & molecular biology 2010 IMEx Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. Only protein-protein interactions imex curation dray-2010-4 in vitro In vitro pull down pull down weight by staining molecular weight estimation by staining weight by staining Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. DIP original experiment: DIP-217660X Nature structural & molecular biology 2010 IMEx Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. Only protein-protein interactions imex curation dray-2010-5 in vitro In vitro pull down pull down weight by staining molecular weight estimation by staining weight by staining Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. DIP original experiment: DIP-217662X Nature structural & molecular biology 2010 IMEx Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray E., Etchin J., Wiese C., Saro D., Williams GJ., Hammel M., Yu X., Galkin VE., Liu D., Tsai MS., Sy SM., Schild D., Egelman E., Chen J., Sung P. Only protein-protein interactions imex curation rad51_human DNA repair protein RAD51 homolog 1 RAD51 RAD51A RECA RAD51 homolog A protein protein human Homo sapiens Human MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD palb2_human Partner and localizer of BRCA2 PALB2 FANCN protein protein human Homo sapiens Human MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQQDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQRTDDTQEHFPHRVSDPSGEQKQKLPSRRKKQQKRTFISQERDCVFGTDSLRLSGKRLKEQEEISSKNPARSPVTEIRTHLLSLKSELPDSPEPVTEINEDSVLIPPTAQPEKGVDTFLRRPNFTRATTVPLQTLSDSGSSQHLEHIPPKGSSELTTHDLKNIRFTSPVSLEAQGKKMTVSTDNLLVNKAISKSGQLPTSSNLEANISCSLNELTYNNLPANENQNLKEQNQTEKSLKSPSDTLDGRNENLQESEILSQPKSLSLEATSPLSAEKHSCTVPEGLLFPAEYYVRTTRSMSNCQRKVAVEAVIQSHLDVKKKGFKNKNKDASKNLNLSNEETDQSEIRMSGTCTGQPSSRTSQKLLSLTKVSSPAGPTEDNDLSRKAVAQAPGRRYTGKRKSACTPASDHCEPLLPTSSLSIVNRSKEEVTSHKYQHEKLFIQVKGKKSRHQKEDSLSWSNSAYLSLDDDAFTAPFHRDGMLSLKQLLSFLSITDFQLPDEDFGPLKLEKVKSCSEKPVEPFESKMFGERHLKEGSCIFPEELSPKRMDTEMEDLEEDLIVLPGKSHPKRPNSQSQHTKTGLSSSILLYTPLNTVAPDDNDRPTTDMCSPAFPILGTTPAFGPQGSYEKASTEVAGRTCCTPQLAHLKDSVCLASDTKQFDSSGSPAKPHTTLQVSGRQGQPTCDCDSVPPGTPPPIESFTFKENQLCRNTCQELHKHSVEQTETAELPASDSINPGNLQLVSELKNPSGSCSVDVSAMFWERAGCKEPCIITACEDVVSLWKALDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSSDDESEKQVLLKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQGMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHKAYSEMGLLFIVLSHPCAKESESLRSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILTSGTIAIWDLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLAGQKDGNIFVYHYS q96b01-2 RAD51-associated protein 1 RAD51AP1 PIR51 RAD51-interacting protein protein protein human Homo sapiens Human MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST Ref.3 (AAH05973) sequence differs from that shown due to a frameshift in position 59 palb2-rad51-2 3214933 N/A 3214938 unspecified role unspecified role prey prey ecolx Escherichia coli N/A 3214939 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false trini Trichoplusia ni (Cabbage looper) Cabbage looper direct interaction direct interaction false false false palb2-rad51ap1-1 3214934 N/A 3214940 unspecified role unspecified role prey prey MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecolx Escherichia coli N/A 3214939 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false trini Trichoplusia ni (Cabbage looper) Cabbage looper direct interaction direct interaction false false false rad51ap1-rad51-2 3214935 N/A 3214938 unspecified role unspecified role prey prey ecolx Escherichia coli N/A 3214940 unspecified role unspecified role bait bait MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false Region 121-335 Region 121-335 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false palb2-rad51-3 3214936 N/A 3214938 unspecified role unspecified role prey prey ecolx Escherichia coli N/A 3214939 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 101-184 Region 101-184 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rad51ap1-palb2-1 3214937 N/A 3214940 unspecified role unspecified role bait bait MBP-tag MBP-tag mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecolx Escherichia coli N/A 3214939 unspecified role unspecified role prey prey GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false trini Trichoplusia ni (Cabbage looper) Cabbage looper direct interaction direct interaction false false false